@PCrowleyDO I said i would never use the nuclear option with our friendship.
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Matthew Brigmon
1.8K posts
Matthew Brigmon
@MBrigmon
Infectious disease and Critical care physician @UTHealthSA @UTHealthSA_ID @uthsa_pccm
شامل ہوئے Eylül 2010
576 فالونگ472 فالوورز
@AmirStocksMD @SeeFisch You are going to have to justify that statement, it is wild.
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Quantitative Microbial Cell-Free DNA Sequencing from Plasma: A Potential Biomarker for the Diagnosis of Staphylococ… pubmed.ncbi.nlm.nih.gov/40066816/
🫀 Well done AW and colleagues. #CIEDinfection. #staphylococcal. Thank you. @MayoClinicINFD @S_Chesdachai
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@JuniorMosimann @ABsteward What about “These results support consideration of 1 year of suppressive valacyclovir treatment for HZO.” Do you not understand???
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🆕💫ZEDS RCT
Low-Dose Valacyclovir in Herpes Zoster Ophthalmicus #idxposts
jamanetwork.com/journals/jamao…
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@Factor_XII Didn’t have it back yet. Tapped the knee before blood was drawn by nurses.
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EM people: who’s calling ortho based on the gross look of this knee tap, and who’s waiting for the cell count and gram stain? Ortho people: you want to be called before of after the lab results?
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@HeartOTXHeartMD @MattWhite_95 You are going to like it out there.
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@MattWhite_95 Greenville, SC. PRISMA Health
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Going to miss my people and patients here.
Looking forward to what God’s got planned for my new team and I.
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@luisfgiraldo Sounds like it should be tested in a randomized clinical trial. That would be something.
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Artificial Intelligence (AI) for Safer Extubation Decisions! Our latest study shows that Machine Learning can help doctors decide when to safely remove ICU patients from ventilators. Our AI models achieved up to 95% accuracy! 📖 Read more: bit.ly/3X7N7HN
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@ChrisTo51777090 @SenSanders About not being clear about if vaccines cause autism?
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@MBrigmon @LadowTiffany Trained in IM/ID/crit AND millennial slang????
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Will always amplify shade thrown at cefdinir ! Let me help you pick something else.
Journal of Hospital Medicine@JHospMedicine
Cefdinir might be popular, but it's rarely an appropriate choice for common infections. Quality over quantity! 📉💊 #ChooseWisely #TWDFNR 🔗: doi.org/10.1002/jhm.13… 🖼️: #VisualAbstract by @ajchinn ✍️: @ JHospMedicine @TWDFNR @SIDPharm @katie_b_olney @bill_olney @HowardJoel
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@pulmtoilet @LadowTiffany I gave it a little young person zhuzh and call it capdinir
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@TheSurajKannan @soupvector @IdVilchez I think the other thing that irks some of us is the studies that favor fidax for recurrence tend to have someone with a COI with merck. The opt 80 stopped at 4 weeks for recurrence. I saw a positive article today in jid for fidax by the same group.
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@soupvector @MBrigmon @IdVilchez A bit surprised by that - didnt that opt-80 trial (or whatever the name was) show lower rate of recurrence with fidax over vanc? I figured the reason we favor vanc (even extended vanc regimens) over fidax at jhh was cost.
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I was informed today by my surgical colleagues that their boards state that fidaxomicin is better than vancomycin for c diff. Is that a consensus in the ID community?
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I prescribe ivermectin more than most doctors.
Because I am an infectious diseases specialist so I use it for a range of parasitic infections in patients referred to me.
I never use it to treat cancer because a) I'm not an oncologist and b) it doesn't treat cancer
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@BradSpellberg @DrToddLee @StevenMathern @costplusdrugs Somehow i was being told that we should be giving it to all our patients over 65 and immunocompromised by non id physicians.
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@DrToddLee @StevenMathern @MBrigmon @costplusdrugs Depends on what is meant by "better". Fewer relapses if used UP FRONT (no evidence after prior courses of Tx). But the NNT to prevent a relapse is 10. And no improvement in up front cure or mortality. As Dr. Lee says, current pricing doesn't make sense given this NNT.
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@DrToddLee @StevenMathern @BradSpellberg @costplusdrugs We don’t have the recurrence rates locally at our institution that others report. For us it is stupid to start someone on fidaxomicin unless they have failed vanc. In most cases i doubt the diagnosis to begin with.
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@StevenMathern @MBrigmon @BradSpellberg It is not priced properly. Especially since @costplusdrugs sells Vanco for ~$1 a capsule.
I do suspect fidaxomicin pulse taper is in need of further study. We have new data coming to this space at ESCMID 2025.
academic.oup.com/jacamr/article…
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A thousand replies and not one human study showing that ivermectin treats cancer. Zero. Not even a small case series.
The published evidence is mostly in vitro studies where cancer cells are killed by a dose of ivermectin that would also kill humans.
Not looking promising…
Nick Mark MD@nickmmark
Hey ivermectin cures cancer folks: I’d love to see this “evidence” you keep talking about Do you mind sharing the best article in support of that? Two things: 1️⃣Post the link 2️⃣say whether the study was performed in cell culture, animal model, or humans. Thanks.
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I have a patient who is on ertapenem for esbl organism osteomyelitis. @UHC approved 4 wks of antibiotics but now is asking for more out of pocket costs from the patient for the last 2 weeks bc of the new year. Why are you so non compassionate?
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@nickmmark The timeline explanation made it sound like most ai experts thought no one knows when but probably longer than you think.
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Was listening to a podcast where two AI optimists were debating the likelihood that an AI has built a Dyson sphere by 2030. One suggested a 15% chance!?! Another thought that was too low!?!?
These are *insane* estimates that seem like a recipe for certain disappointment..
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