Jeffrey Smith

@rorynotsorry @TheRealOpsGuy @x3ideRaven I believe that Pharma will step up government pressure to shut down ROU. Interception at customs, Shutting down free speech, shutting down banking, removal from internet. Moving to telegram and bit coin will eventually be the only way to go.

@TheRealOpsGuy @x3ideRaven I have a telegram group for Crush Research... send a message to socialmedia@crushresearch.com with proof you are a customer and my social media manager will get you in.

Et tu X? What sort of person would report this post. And why would X think it was worth a permanent suspension? Luckily appeal went through, though I had to remove it. Going to create a separate Crush Research account just in case.

@ThrillaRilla369 Catheter to drain my bladder. Everybody in the emergency room waiting room all decided at the same time. “I am not that bad, maybe I’ll just go home.l

What's the most physically painful thing you've ever experienced in your lifetime? I’ll go first: the kidney stone I’m currently trying to pass 😿

@rorynotsorry You mean the ones that only sell PT-141?

Just invented a new word.... popup vendors... no explanation needed.

@rorynotsorry I am hoping KLOW will make a difference in my workout and Oxytocin in my relationships. (Not Autisitic or ADHD, at least no one has ever proved it)

Though obviously not a Doctor I count myself (ironically) as a peptide skeptic outside GLP1s, but my skepticism is rooted more in risk / cost analysis. Outside of biohackers who are very attuned to their bodies, I am not sure if the tangible benefits of many peptides justify the effort and cost. 🧵

@rorynotsorry Free Oxytocin!

The reason that Papas rule is because we are quite content to sit by ourselves on a couch holding a baby. I might take a nap too.

@tabi4227 @PeptideBase Never heard Reta does anything for mitochondria. Is there somewhere I can learn more about this

@PeptideBase Reta rebuilds enterly the mitochondrial function, it’ like rewiring the system to a new set point , a better longevity with anti age properties. So the answer is pretty clear to me 💥💪

Reta or Tirzepatide which would you build an entire year around, and why? No wrong answers. Curious where the room actually lands.

@rorynotsorry Quick, Quality or Price. Choose two. You have chosen two, Quality and Price, but as a customer I have to wait for the product to drop. You have chosen two, you have chosen your business plan. Don’t worry be happy. youtube.com/shorts/RSGFSlK…

Is this true? Apparently I need to stop testing as much or raise my prices.

@micheal_ws18 Bulgarian Split Squats. I think the Commies sent them over as some sort of diabolical evil plan.

What’s the hardest exercise in the gym for you?

@bumpy_bnolan69 @SGTWipper1Each Yeah, me too.

@SGTWipper1Each I would try other choices before making Ibuprofen a habit - kidneys do NOT repair themselves if damaged. The V.A. used to prescribe strong Ibu to me for my lumbar stenosis that I ate like candy, and now I have Stage 3 kidney disease.

Back hurts today. Should I: A. Take 800mg Ibuprofen B. Change my socks C. Drink water D. Drive on

@rorynotsorry I am up to 6 mg a week. 4mg on Sunday and 2 mg on Thursday. Fits my lifestyle. Only 15 pounds in three and half months though. Hoping to raise that to 6 pounds a month for at least 4 months. Need to lose another 50 pounds or so.

If you have used Retatrutide to lose a decent amount of weight (20lbs or more) What is or was the optimum weekly mg that you have found effective.

@DAMxTARO @pepfessions Right! Sorry. 1 to 2 pounds a week. More than 4 pounds a month less than 8. Strange but true, my weight comes off like it is in lumps. My chart looks like -1 O O -3 or something weird like that.

@Qazulight @pepfessions 1-2 pounds a month?? That would be slow doing it naturally. 1lb a week is good.

6 months on reta, down 60 lbs, about 25% of my bodyweight. I look better than I have in my adult life and people keep telling me how happy I must be. here's what nobody puts in the before/afters: it didn't just kill my appetite, it killed my drive. the same thing that quiets the food noise quiets everything. I used to attack my mornings. now I have to schedule motivation like it's a meeting. lost the weight, lost the fire that used to come free with being hungry. nobody warned me they were wired to the same switch.

@theonejvo @linear My wife is using AI to track food, migraines and calendar. Three apps integrated. This is the smart phone all over again. Try and remember how many things you no longer have due to the smart phone

Can someone please explain to me how there is any reason to keep using apps like @linear & other project management tools when you can now just build your own, integrate it into your existing workflows and software?

@CharlesMullins2 Have you followed David Sinclair at all? What you are saying IS the plan. It has been the plan.

This is exciting, but it raises a bigger question. If we can use cellular reprogramming to regenerate aging neurons in the optic nerve, why stop at the eyes? Aging isn’t just one organ breaking down it’s a whole-body process. What happens when we apply the same approach to brain cells, spinal cord tissue, heart muscle, or joints? If this technology can safely turn back aspects of cellular aging in the eye, could we eventually do it across multiple systems at once? Or are there major biological hurdles that make the eye a special case for now? What do you think is this the beginning of treating aging more broadly, or will it stay limited to specific tissues for a long time?

This is the story of four proteins that can rewind aging, and the $4 billion racing to put them inside a human being. For a century, biologists treated aging like a rusting car. Parts wear out, damage piles up, no reverse gear. A small group now argues that's wrong. Much of what looks like permanent damage, they say, is really a software problem, and software can be rewritten. Every cell in your body carries identical DNA. What makes one a neuron and another a skin cell is a second layer of information sitting on top, telling each cell which genes to run. The heretical claim is that aging is the slow corruption of that information. And in 2006, a failed orthopedic surgeon named Shinya Yamanaka found four proteins that can retrieve it. His recipe could take a fully specialized cell and walk it all the way back to a blank, become-anything state. It won him a Nobel. Then scientists found something stranger. Turn the factors on briefly, not long enough to erase a cell's identity, and old mice get younger by every measure, and live about 30% longer. A heart cell stays a heart cell. Just younger. The boundary with cancer is razor thin. Run the factors too long and you manufacture tumors in bulk. The whole trick depends on not finishing. Now the money has arrived. Bezos backs @altos_labs. Sam Altman seeded @RetroBio_. Brian Armstrong co-founded @newlimit. David Sinclair's Life Biosciences got through the door first. In January 2026, its eye therapy became the first cellular reprogramming treatment ever cleared for human testing. The realistic prize isn't immortality. Nobody's living to 300 on an eye injection. It's compression of morbidity, squeezing the sick, declining years at the end of life into a shorter window. The question has finally narrowed. Not "can a cell be made young?" but "can a patient be made well?" By the early 2030s, we'll know. Read @QwQiao's essay on the Yamanaka factors below.

@alliance I can’t get the essay to open

@AZLATIN13 @mannyjplays I was taking 4mg on Sunday night. By Friday I was getting hungry, By Saturday night it was grilled oysters and beer. So I added 2 mg on Thursday morning. Seems to help. Enough hunger to refeed and eat out with friends but still have control.

@mannyjplays Not sure if this has been a subject I haven’t came across on here but has anyone talked about or tried splitting their doses 2-3 a week instead of one to possibly avoid peaks of nausea or hard side effects like appetite suppression fading compared to split having flatter levels?

📈 Reta Update: Moved from 5mg to 6mg this week I’ve been at 5mg for the last 3 weeks, and over the past week I noticed the appetite suppression starting to fade. The food noise wasn’t completely back, but I found myself thinking about snacks more often and having more urges to eat between meals. I wasn’t bingeing or overeating, but I want to stay ahead of those cravings rather than wait for them to become a bigger issue. At 210 lbs with a goal weight of 170 lbs, I still have a significant amount of body fat to lose, so I believe I can continue benefiting from a gradual dose increase. As always, I’m focusing on using retatrutide as a tool alongside good nutrition, adequate protein, and staying active. Looking forward to seeing how 6mg feels over the next few weeks. 💪

@rorynotsorry I had a feeling about the KLOW. I have been studying on it. The holy trinity is sleep, exercise and diet. Reta takes care of the food noise so diet, Exercise causes pain during recovery - KLOW helps with that. So it would seem the second most important peptide.

Ok you damn customers. You got me with the KLOW yesterday, I blink its gone. Well... I only listed 1/2 of it... so there.. I will list the rest Friday with my next drop. I know what you are thinking. Try us, we will buy that up too... your prices are too good... well, jokes on you. I just got another batch in... I will have more in 7-10 days... you can't beat me. I will keep up with your insatiable demand.

@rorynotsorry I don’t know about sweating the delayed thing. Of course I am a ine trick pony with a year supply in the freezer. If I was hurting and wanted my Wolverine Stack NOW, I might have a different attitude.

This is too much pressure. 5% of orders get delayed or something. I’m just making up numbers. Now I gotta figure out who he is and make sure his order doesn’t get delayed so I don’t get dragged. Then again in all seriousness, everybody’s order that gets delayed keeps me up at night.

@muheediva01 AIr Conditioning on the Gulf Coast.

FOR THOSE WHO DIDN'T GROW UP PRIVILEGED, NAME SOMETHING YOU THOUGHT WAS A LUXURY WHEN YOU WERE A KID