The SchietiLab
143 posts
The SchietiLab
@SchietingerLab
Putting the FUN into T cell dysFUNction; unleashing the power of T cells to fight cancer!
New York, NY شامل ہوئے Eylül 2015
268 فالونگ2K فالوورز
@Zihai @MingLiLab Brilliant mind and an awesome colleague! Congrats Ming! 👏
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Beautiful piece, and an insightful discussion with @MingLiLab on how to harness the power of immune system to fight cancer. Ming is a brilliant mind in the field!! medicalxpress.com/news/2023-11-q…
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Congratulations on this amazing piece of work @philiplabvandy @MRudloffMSTP & team @VUMC_VCI 🎉👏. Paradigm-shifting findings! Lots to think about...BRAVO!!!
Philip Lab@philiplabvandy
We are excited to share our work published today in @NatImmunol by @MRudloffMSTP, the whole @PhilipLabVandy team @VUMCDiscoveries, and in collaboration with our fantastic computational biology collaborators @dbetel and his group @WeillCornell. 1/7 nature.com/articles/s4159…
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@nevillesanjana @NEJM Terrific study with super cool & unexpected gene LTBR. Can't wait to see what's coming next....
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Thank you @NEJM (& Andrea @SchietingerLab ) for profiling our lab's recent work in Clinical Implications of Basic Research: nejm.org/doi/10.1056/NE…
We are thrilled by the possibility of bringing modifier-enhanced T cell therapies to the clinic!
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The SchietiLab ری ٹویٹ کیا
Enhancers are known to increase mRNA level. It is often assumed that this happens through increased transcript production. We deleted an endogenous enhancer of PTEN. We found that they also regulate poly(A) site cleavage activity and change expression of alternative 3′UTRs.
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They did it again...another brilliant new paper from our colleagues @MingLiLab and collaborators! Congrats!!! @MSKCancerCenter
Ming Li@MingLiLab
Repurpose T cell self-reactivity for #cancer #immunosurveillance . Check out our new study @Nature by brilliant @CancerResearch fellows Chun Chou and @XianZhang2016 with help from @chirag_msk @JoshSmithMDPhD and other @MSKCancerCenter colleagues. rdcu.be/cLLaG
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@philiplabvandy @VanderbiltU @immuno_minna @VandyBiochem @VUMC_VCI Congrats @philiplabvandy and @immuno_minna!
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We can't be prouder of our @vanderbiltU UG extraordinare @immuno_minna on being awarded a 2022 #NSFGRFP! We're looking forward to her senior thesis presentation on 4/29--stay tuned! @VandyBiochem @VUMC_VCI
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Thrilled to finally share this labor of love from @Moran_Lab & @ZhengXiaCompBio just out in @Nature. Team science @OHSUKnight=incredible! Take home: Testosterone suppresses T cell function within the tumor and limits the effectiveness of immunotherapy. rdcu.be/cJE4H
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What are you doing on Friday 3/11 @ 2:30 ET?
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Philip Lab@philiplabvandy
Tune in for @TheScientistLLC live webinar this Friday 3/11 2:30-4:00 pm ET with @Philiplabvandy @VUMC_VCI @VUMC_Cancer and Dr. Ben Youngblood @StJudeResearch to hear all about T cell dysfunction/exhaustion in cancer! A Spotlight on T Cell Exhaustion the-scientist.com/sponsored-webi…
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@lydfinley @Nature @paigearnold2 @__btjackson @GSKGradSchool @MSKCancerCenter It's out 🥳!!! Brilliant. Congratulations to @lydfinley & Co! @MSKCancerCenter
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Our new work describing a “non-canonical” TCA cycle that is engaged in a cell-state dependent manner is out today in @Nature nature.com/articles/s4158…. Congratulations to lead authors @paigearnold2 @__btjackson @GSKGradSchool @MSKCancerCenter. A few highlights:
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@mmmdonuts76 You should have more followers now that you are Partner!
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Excited to be joining the partnership at Latham and to continue working with a world-class group of IP litigators!
Latham & Watkins LLP@lathamwatkins
Congratulations to our new partners. Wishing all much success in the next chapter of their careers. t.lw.com/n8kecz
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BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint-Therapy Efficacy aacrjournals.org/cancerimmunolr…
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A must read: Oncogenes and Immune Evasion. Congrats to @jjroetman and @philiplabvandy !
Philip Lab@philiplabvandy
1/ Excited to share our review: Viral and Cellular Oncogenes Promote Immune Evasion @oncogenejournal @jjroetman @VUGradSchool and MKI Apostolova @VanderbiltU @VUMC_VCI @VUMC_Cancer @VUMC_Medicine doi.org/10.1038/s41388…
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And it’s out!! science.org/doi/10.1126/sc…
Ever wonder what happens when patients stop responding to novel therapies? Here @TheHutchChapuis @fredhutch we have been working to find out why. Our paper reveals a mechanism of immune escape in an unusual patient case.
🧵👇 1/14
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@LewisLabMSKCC @nagle_roni @k_hens Congrats again to @nagle_roni and @LewisLabMSKCC ! Terrific work!
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Roni's @nagle_roni last paper from her PhD where we visualize human CD4+ T cells in brain tumors and provide non-invasive quantification of CD4+ T cell distribution on the organismal scale. @SchietingerLab @k_hens mct.aacrjournals.org/content/early/…
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@UshmaNeill @whitefishlab Only one word: WOW!!! What fabulous science 🐟
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What terrific news!!! Congratulations @MingLiLab - our very own 16th floor AAAS fellow!!!
Yes @tmhohl71 : handsome celebration preparations are in the works! 🎊🎉🍾🥂
Tobias Hohl is now @fungalspore.bsky.social@tmhohl71
Congratulations to @sloan_kettering immunologist and colleague Ming Li @MingLiLab on his election to AAAS Fellow! Richly, richly deserved - This calls for a handsome celebration. Paging @SchietingerLab ... @JustinPerryPhD @huselab @MichaelGlickma1 @DiehlLab_MSK
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