Chandra Menendez, PhD

So important to enhance diagnostic and therapeutic insights to educate clinical guidelines, support insurance coverage for IVIG, and emphasize the importance of interventions such as IVIG and or antibiotic use when needed.

This work is crucial for better understanding and identifying infection-triggered autoimmune mechanisms.

📢Made the news! 📢 Our PANDAS/PANS research is staying strong. Grateful to continue our important work. Happy to be a part of bridging the gap between infection, autoimmunity, and neuropsychiatric symptoms.

Our research paves the way for precision medicine approaches that address underlying immune dysfunction in PANDAS, PANS, Sydenham chorea, the neurologic and neuropsychiatric component of Rheumatic Fever, and related conditions.

@hubermanlab Does this apply to high energy ADHD year olds who like to push the Boundaries and easily get agitated, frustrated and upset. Asking for a friend 😅

The new Huberman Lab episode is out: Dr. Becky Kennedy: Overcoming Guilt & Building Tenacity in Kids & Adults This episode is available in full on X, YouTube and all podcast platforms. (0:00) Dr. Becky Kennedy; LA Fires (3:13) Emotions, Parents & Kids, Information, Tools: Story; “Right to Notice” (11:24) Sponsors: Wealthfront & Our Place (14:25) Empathy, Kids & Parents (18:33) Sturdiness, Pilot Analogy, Tool: Parental Self-Care (26:34) Emotions, Rigidity, Moody vs Steady Kids, Siblings (32:51) Emotion Talk, Crying; Eye Rolls, Tools: Not Taking Bait; Discuss Struggle (39:26) Parent-Child Power Dynamics, Tools: Requests for Parent; Repair (48:50) Sponsors: AG1 & Joovv (51:39) Power & Authority, Tools: Learning More; Parent Primary Job & Safety (59:16) Statements of Stance, Actions vs Emotions; Values, Behaviors & Rigidity (1:05:59) Guilt, Women; Tools: “Not Guilt,” Tennis Court Analogy & Empathy (1:15:46) Sponsors: LMNT & Eight Sleep (1:18:41) Guilt, Relationships, Tool: Naming Values Directly (1:26:06) Locate Others & Values; Sturdy Leadership; Parenting & Shame (1:31:36) Egg Analogy & Boundaries; Tools: Frame Separation; Pilot & Turbulence; Safety (1:39:30) Projection, “Porous”; Tools: Gazing In vs Out, Most Generous Interpretation (1:45:51) Tools: “Soften”; Do Nothing & Difficult Situations; Proving Parenting (1:51:05) Gazing In vs Out, Scales; Self-Needs & Inconvenience (2:00:05) Stress & Story, Nervous; Relationships vs Efficiency (2:08:46) Technology, Relationships, Frustration Tolerance, Gratification (2:15:18) Slowing Down, Phones, Frustration, Capability (2:21:42) Immediate Gratification, Effort & Struggle, Dopamine (2:29:25) Confidence, Board Games, Parental Modeling (2:34:04) Ultra-Performers & Pressure, Emptiness (2:41:29) Trying Things, Unlived Dreams, Frustration Tolerance, Tool: Learning Space (2:51:08) Learning & Building Frustration Tolerance, Tantrums; Feelings & Story (3:03:00) Tool: Using Story; Shame, Punishment (3:12:55) Leadership & Storytelling, Tools: Asking Questions; Songs & Learning (3:23:21) Miss Edson, Momentum, Tool: Small First Steps (3:30:15) Tools: Parents & Starting Point (3:36:29) Good Inside, Zero-Cost Support, Spotify & Apple Follow & Reviews, YouTube Feedback, Sponsors, Social Media, Neural Network Newsletter Includes paid partnerships.

Thrilled to see @BrainInflammCo spotlighting the link between childhood infections, autoimmunity, and symptoms like tics, OCD, and movement disorders! 🎯 Discover how our latest findings shed light on these mechanisms: @JCI_insight insight.jci.org/articles/view/…

@BrainInflCollab @NNwppn @PANDASPPN @PANSPANDASUK @EncouragePandas Thanks to @JCI_insight @PANDASPPN, The PANDAS Network, The BRAIN Foundation, and everyone who supports this important work to advance our understanding of neuropsychiatric disorders and PANDAS/PANS. Your collaboration makes all the difference!

\ The Discovery: Scientists from the University of Oklahoma Health Sciences Center found that PANDAS/PANS children with tics and OCD have autoantibodies targeting the dopamine receptor 1 (D1R). Meanwhile, those with Sydenham chorea (whiplash-like movements) have autoantibodies targeting dopamine receptor 2 (D2R). Read the paper here: buff.ly/4eqOKWG

Seemingly benign childhood infections (like strep throat) can cause a spectrum of neurological symptoms (in some) such as: - tics - OCD - uncontrolled movements (Sydenham chorea) A brand new paper (likely) reveals why...🧵 @NNwppn @PANDASppn @PANSPANDASUK @EncouragePANDAS @LucyMcDonald

@BrainInflCollab Great in theory but not in actuality. Would be specific to patient and not practical for children.

We envision a world where CAARTcell technology can cure all autoantibody-mediated autoimmune diseases. Please like and share the content if you found this informative. Also, consider signing up for our free newsletter where we provide deeper scientific insight 2x per month.

One of the biggest discoveries in treating autoimmune encephalitis was recently made. It has the potential to cure autoimmune diseases caused by autoantibodies... 🧵

· Promotion of Inflammatory and Pathogenic Bacterial Growth: Diets high in UPFs, often characterized by increased saturated fats, sugars, and additives, can lead to changes in gut microbiota composition. This includes a decrease in bacteria that support barrier integrity

These SCFAs help maintain the intestinal barrier and modulate immune responses. High-UPF diets, which are typically low in dietary fiber, can reduce SCFA production, leading to weakened intestinal barriers, increased translocation of harmful molecules.

My PSA for the day: Why Eating the Right Foods is Crucial—Literally for Our Guts nature.com/articles/s4157…

@BrainInflCollab 👍

@More4Science Quin is excreted so it can be detected in the urine. ncbi.nlm.nih.gov/pmc/articles/P…

Chronic inflammation slows the production of serotonin, steering it instead toward self-destructive quinolinic acid production. This is why quinolinic acid is a neurotoxin...🧵

My @ImmunologyAAI colleagues and I thank Senator @cindyhydesmith for an excellent meeting supporting immunology and biomedical research. #PPPFHillDay, we depend on #FundNIH

Enjoyed meeting with @stephaniebice office staff about the importance of immunology and biomedical research. Thank you @ImmunologyAAI , #PPFHillDay for this opportunity and for #FundNIH support!