Mark Histed

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Mark Histed

Mark Histed

@HistedLab

Aim to understand brain networks and brain wiring, using lasers & neuro AI. Lab head, @NIH. Prev: policy for @democracypolicy. Personal views. Not a lab acct.

Washington, DC 加入时间 Mayıs 2013
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Mark Histed
Mark Histed@HistedLab·
New preprint, on 'sequence filtering'. Led by @CianaDeveau, Z Zhou. We see this as a key step forw on how cortex works. All cortical areas have dense exc-exc recurrent connectivity. What do these connections do, esp in sensory ctx? Our data say: they do dynamics/time. 1/4
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Mark Histed
Mark Histed@HistedLab·
NIH has long engaged the scientific community in a democratic way. That's a good thing, and it's under attack. New post by me, about why NIH's peer review process and advisory panels are pretty unique across gov't, and why they're so important.
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Mark Histed
Mark Histed@HistedLab·
has replaced most of those metrics. That’s proper because that’s the concept most of the metrics were trying to get at: ability to find mean changes in the presence of noise. (Some empirical neural tuning metrics remain. And I’m distinguishing these from true neural tuning fns.)
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Mark Histed
Mark Histed@HistedLab·
Watching Grace Lindsay give an excellent talk about neuroscience and interpretable AI. One thing that occurs to me listening—a historical note from neuro. The field used to use all kinds of hand-tuned selectivity metrics: d’, R2, mutual info. But now cross-validated decoding…
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Jason Shepherd
Jason Shepherd@JasonSynaptic·
I have been having the same convos offline, but many (most?) scientists don't want to stick their necks out right now...at least publicly. IMO, we are past that point. Glad for folks like Mark who are literally facing govt retaliation but are still informing us!
Mark Histed@HistedLab

Writing out a conversation I’ve been having a lot at this conference: Things in US science are far, far worse than people know. Far worse than even other scientists know. 1/

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Anshul Kundaje
Anshul Kundaje@anshulkundaje·
Pathological megalomania may provide some kind of LFG advantage ... until it doesn't. At some point, u start making stupid decisions if u don't introspect. I think this is becoming quite clear with many self-proclaimed "great men" in the tech and VC space.
David Senra@davidsenra

Great men of history had little to no introspection. The personality that builds empires is not the same personality that sits around quietly questioning itself. @pmarca and I discuss what we both noticed but no one talks about: David: You don't have any levels of introspection? Marc: Yes, zero. As little as possible. David: Why? Marc: Move forward. Go! I found people who dwell in the past get stuck in the past. It's a real problem and it's a problem at work and it's a problem at home. David: So I've read 400 biographies of history’s greatest entrepreneurs and someone asked me what the most surprising thing I’ve learned from this was [and I answered] they have little or zero introspection. Sam Walton didn't wake up thinking about his internal self. He just woke up and was like: I like building Walmart. I'm going to keep building Walmart. I'm going to make more Walmarts. And he just kept doing it over and over again. Marc: If you go back 400 years ago it never would've occurred to anybody to be introspective. All of the modern conceptions around introspection and therapy, and all the things that kind of result from that are, a kind of a manufacture of the 1910s, 1920s. Great men of history didn't sit around doing this stuff. The individual runs and does all these things and builds things and builds empires and builds companies and builds technology. And then this kind of this kind of guilt based whammy kind of showed up from Europe. A lot of it from Vienna in 1910, 1920s, Freud and all that entire movement. And kind of turned all that inward and basically said, okay, now we need to basically second guess the individual. We need to criticize the individual. The individual needs to self criticize. The individual needs to feel guilt, needs to look backwards, needs to dwell in the past. It never resonated with me.

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Mark Histed
Mark Histed@HistedLab·
Writing out a conversation I’ve been having a lot at this conference: Things in US science are far, far worse than people know. Far worse than even other scientists know. 1/
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Mark Histed
Mark Histed@HistedLab·
@j_kalla @verasight_data @mcuban "most electable" defined by assuming public opinion is fixed and will not be influenced by the nonlinear system of information and public debate over the next few years :)
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Mark Histed
Mark Histed@HistedLab·
- Also I'm having this convo many times over, to extent I'm boring my friends, who have heard it repeatedly in last few days. So I'm writing it out no private agency info disclosed here, this is opinion or public info or I am exhorting you to talk to others feel free to comment
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Mark Histed
Mark Histed@HistedLab·
@CosyneMeeting But you can't build a talent and innovation industry if you wall it off from the world.
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Max Hodak
Max Hodak@maxhodak_·
everyone is always like, you should change the world, you should have an impact, it'll be great, let's change the world you would never believe the degree to which the world does not want to be changed
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