Pascal Michael, PhD

@therealRYC Won't the altered vascular activity simply secondarily affect neuronal activity anyway via changed perfusion, so original data might not be revealing direct psychedelic-neuron effects, but the downstream results of e.g. reduced activity in executive networks would still converge?

🚨 Holy. Mushrooms. The entire field of psychedelic neuroimaging may have just gotten everything wrong. Psilocybin decouples neurovascular response from neuronal activity. That means fMRI studies on hallucinogens could be picking up vessel, rather than neuronal effects.

Can I get an invite @producer_ai?

Our latest paper on DMT phenomenology led by @PIMMp7 exploring the mis/matches with near-death experiences, showing that while 95% on DMT had at least one NDE feature, many classic NDE features were absent & only a very few had NDE-like trips in any way doi.org/10.3389/fpsyg.…

Dr. Pascal Michael, PhD, is a lecturer and researcher at the University of Greenwich, specializing in psychedelics, NDEs, entity encounters, and UFOlogy. His groundbreaking work explores the connections between these extraordinary human experiences. 👉ContactInTheDesert.com

@drdluke Thanks Dr D!

@alieninsect @drdluke 😂

@drdluke @PIMMp7 So you’re telling me DMT probably *isn’t* released during the dying process? I’m not surprised, but it’s also something of a relief… 😮‍💨

My publication of part of my thesis recently out on comparing changa psychedelic experience with near death experiences uniquely amongst those who've had both alongside @drdluke and Dr. Oliver Robinson

@JayCKing78 @InquireAnomalus @lesliekean @MorphoTime @EngagingThe @GallaudetTim Is there an option for online attendance ? Thanks!

The Alef Trust's @aleftrust Professional Certificate in Psychedelics, Altered States and Transpersonal Psychology, run by @drdluke and myself, is eagerly awaiting your application for our Feb '24 intake! 🎓🥸 instagram.com/reel/C0NMvlwoI… aleftrust.org/professional-c…

@SarahJanes77 @thenightshirt Thanks Eric! What might this look like? I'm tempted by the idea of some even in the universe causing itself. Akin to the big crunch model. And alluded to by your quantum suggestions that all events, not just precognitive ones, are caused by influences from their future...

#DreamPalace afterparty at the Peach Bungalow in Palaia #Epidavros with @thenightshirt @PIMMp7. Eric, Pascal asks - can the #universe itself be considered a #timeloop? #isthisadreampalace

@cornhairx My research is available on @ResearchGate: researchgate.net/publication/36…

@SimonAmstell Hi Simon. Good show. You said God was a vulnerable alien who created the universe to escape their own pain. Interesting! Please elaborate. Kind thanks. :)

🌞🧐Thanks to @bialfoundation, my primary funders, for writing up an article summarising my recent paper in Frontiers with my UoGreenwich supervisors on NDEs and 5MeO 🧐🌞

🔖With the support of the #BIALFoundation, Pascal Michael and collaborators analysed the similarities and differences between a near-death experience, during a coma, and an experience induced by a psychedelic drug. Learn more: bit.ly/SS_NDE

@IHearTheShofar @bialfoundation @Craigweiler Hi there. Im the author :) I dont agree with your statement - the best definition of a classical NDE is that its an altered state of repeatable phenomenology while in a life-threatening state. One need not be clinically dead.

@bialfoundation @Craigweiler NDE, original definition, requires actual inarguable physical death; coma retains consciousness, albeit in an altered state. The individual is alive.

@alieninsect @drdluke Indeed that's what I argued at the end of the paper; those bits n bobs comprising much of the NDE which weren't evinced by the 5MeO are clearly more aligned with DMT content. Which puts a more nuanced spin on Sam Harris' original deconstruction of the same participant

Cool new paper from Pascal Michael @PIMMp7 and Dave Luke @drdluke using thematic analysis to compare NDEs to the 5-MeO-DMT experience. ncbi.nlm.nih.gov/pmc/articles/P… It's interesting that *all* of the identified themes in the 5-MeO-DMT state were also found in the NDE state... Many of the NDE themes missing from the 5-MeO-DMT state seem more DMT-esque to me... Perhaps a 5-MeO-DMT+DMT combo is the way to replicate the NDE???

@_clairobscur @rogeressig @alieninsect @drdluke Wow, crazy. We had very many hyperdimensional constructs in our DMT field study. There's also accounts of formidable spinning multiversal wheel-structures in NDEs (ordinarily associated with salvia - See Smith's talk on Breaking Convention YT channel)

@rogeressig @alieninsect @PIMMp7 @drdluke My first DMT trip took me by surprise with its striking resemblance to a childhood high-fever OBE experience witnessing an enigmatic multidimensional contraption composed of intricate spinning wheels and countless captivating eyes gazing back at me.

@rogeressig @alieninsect @drdluke Interesting. Night terrors seem to be related to becoming conscious (lucid) during a psychologically content-free (empty) state, eg in slow wave sleep. The practice to master this is Sleep Yoga in Tibetan Buddhism. And ketamine (in sheep brain) is shown to elicit this EEG state

@alieninsect @PIMMp7 @drdluke There's childhood 'night terror' experiences that remind me of what's said about NDE & 5MEO.

@beforethecrows @alieninsect @drdluke I don't think it would be quite as simple as that...haha... NN-DMT itself evidently produces 'contentless'/Maximal content Mystical experiences also eg at the peak. But why not, let's try everything 😉

@alieninsect @PIMMp7 @drdluke I believe that would be a good combo candidate. Reads that way to me as well. Very interesting.

@drdluke @alieninsect @alexgreycosm Well perhaps! But as I say in the discussion, endogenous [insert w/e endo psychedelic here] needn't be released and there's a slew of physio barriers, where some convergent downstream higher order neural mechanism with different triggers is likelier

@alieninsect @alexgreycosm @PIMMp7 I see your 5MEO experience and I raise to an NDE. Endogenous wins thanatonautic poker!