The Innovation | Cardiology

Seven unanswered questions about blockbuster weight-loss drugs such as Wegovy and Zepbound. Part of our Year in Review, by @techtyper nature.com/articles/s4159…

In a game-changing development for #malaria #vaccines, single-dose immunization with a genetically weakened whole malaria parasite vaccine achieved unprecedented protection. News & Views from Debashree Goswami & Stefan Kappe @seattlechildren @UWMedicine nature.com/articles/s4159…

When you work out, are you doing too much or not enough? There’s a simple way to know: Your target heart rate If your heart rate is too high, you’re straining. If it's too low, you may want to push yourself a little harder, especially if you’re trying to lose weight.

Our new Harvard/Stanford study out today in Nature Medicine! Our results show language models, while strong at medical exams, stumble when they need to gather patient information through natural conversation - a key finding as healthcare explores AI integration. How to solve? Enter CRAFT-MD.

The latest large language of life #AI model (LLLM) predicts the impact of coding and non-coding DNA variants with scores for all ~9 billion possible single nucelotide variants, from whole genomes across multiple species nature.com/articles/s4158… @NatureBiotech @yun_s_song @gsbenegas @cralbors @chengzhong_ye @UCBerkeley

The effects of GLP-1 drug (semaglutide) on the proteome shows broad impact, potential relevance to many diseases beyond obesity nature.com/articles/s4159… @NatureMedicine

Cancer vaccines to rev up a person's immune response to a tumor are gaining momentum, even vs some of the most aggressive types. One unsettled question: why does the immune system overlook a neoantigen produced by a tumour, but gets activated when it is delivered by vaccine? economist.com/science-and-te…

There is an increased risk of autoimmune diseases after Covid, and 2 constituents of the virome (anellovirus and HHV-6) may help to explain this link nature.com/articles/s4158… @NatureGenet a study of 5 different autoimmune diseases in over 6,300 Japanese individuals with Covid or healthy controls, all w/ whole genome sequencing

Delighted to publish in The Lancet, and with none other than @EricTopol. How do we evaluate the next generation of medical AI? Let's consider a clinical certification pathway -> thelancet.com/journals/lance…

A new Review on artificial touch systems stresses aligning feedback with the brain's learning and adaptation processes to design interfaces that are intuitive, flexible, and better suited to human needs, allowing users to feel and act more naturally. scim.ag/4gFrE01

JUST PUBLISHED: A Magnetic-Responsive Biomimetic Nanosystem Coated with Glioma Stem Cell Membranes Effectively Targets and Eliminates Malignant Gliomas Click here to read the latest free, Open Access article from Biomaterials Research: spj.science.org/doi/10.34133/b…

JUST PUBLISHED: Protein Phosphatase 2A Promotes CD8+ T Cell Effector Function through the Augmentation of CD28 Costimulation Click here to read the latest free, Open Access article from Research: spj.science.org/doi/10.34133/r…

"Non-traditional risk factors for atrial fibrillation: epidemiology, mechanisms, and strategies": explore how unexpected factors impact atrial fibrillation and innovative approaches to prevention and treatment. doi.org/10.1093/eurhea… @ESCardio @ESC_Journals #AF

A Review from @MDLuecken, @SikkemaLisa, @KHrovatin, @fabian_theis & colleagues provides a comprehensive and detailed discussion about how to build and use single-cell atlases. nature.com/articles/s4159…

The wait is over!! We are thrilled to announce that we have chosen Spatial Proteomics as 2024’s Method of the Year! 🥳 For more on Spatial Proteomics and a road map to this special issue, please see this month’s Editorial or read on in this thread. nature.com/articles/s4159…

Our final issue of 2024 is now online cell.com/molecular-cell…

Long naps affect quality of nighttime sleep: Long naps at any time of day can make you sleep less soundly that night. #HarvardHealth #TipoftheDay

High-intensity interval training (HIIT) has been one of the most popular fitness trends for over a decade. It's no wonder. HIIT workouts efficiently boost cardiovascular health, improve metabolism, and burn fat.#HarvardHealth bit.ly/41rjPqn

Whether you're managing your weight or just looking for healthier choices, eating low-calorie, nutrient-rich snacks can keep your energy stable and help you avoid cravings for unhealthy foods. #HarvardHealth bit.ly/3VyA0ym

Cutting back on sugar: Reduce the amount of sugar in your favorite dishes by cutting back gradually until you notice the difference. #HarvardHealth bit.ly/4frfYwO