Murthy Lab

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Murthy Lab

Murthy Lab

@MurthyLab

We are a neuroscience laboratory interested in neural mechanisms of social communication.

Princeton, NJ Joined Nisan 2015
196 Following2.2K Followers
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Murthy Lab
Murthy Lab@MurthyLab·
Excited to announce the completion of the first adult brain connectome - FlyWire is the neuronal wiring diagram of a Drosophila melanogaster brain with >130K neurons and >32M synapses. Explore at codex.flywire.ai. Check out the preprints:
Sven Dorkenwald@sdorkenw

We are releasing a whole-brain connectome of the fruit fly, including ~130k annotated neurons and tens of millions of typed synapses! Explore the connectome: codex.flywire.ai Reconstruction paper: biorxiv.org/content/10.110… Annotation paper: biorxiv.org/content/10.110… 1/6

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Sebastian Seung
Sebastian Seung@SebastianSeung·
How are neurons activated by sensory stimuli? For the past century, the only method for addressing this question has been neurophysiology.
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GRC/GRS NMAC
GRC/GRS NMAC@GRC_NMAC_2024·
We are excited to announce that registration is open for the 2024 Neural Mechanisms of Acoustic Communication Gordon Research Conference. The preliminary program is now live: grc.org/neural-mechani… We invite everyone to apply! See you @ Sunday River, Maine, May 19-24, 2024.
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FlyWire
FlyWire@FlyWireNews·
This might make you think twice next time you reach for the fly swatter. The whole brain wiring diagram of the fly! All 140,000 neurons and their 50M synapses are available to explore in Codex, the Connectome Data Explorer: codex.flywire.ai #sfn23
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Benjamin Cowley
Benjamin Cowley@BenjoCowley·
We've updated our preprint on finding one-to-one mappings of DNN neurons and real visual neurons of fruit fly. --> 2x silenced data with new LC31 neuron type --> more LC neural recordings --> FlyWire connectome --> knockout training simulations Enjoy! tinyurl.com/5n7t6tpv
Benjamin Cowley@BenjoCowley

Excited to share a new manuscript! Deep nets are great at predicting visual neurons. Yet, they are unable to tell us which artificial neuron directly corresponds to a biological neuron… until now! biorxiv.org/content/10.110… (yes, that is indeed a fictive female fly, good guess!)

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Sebastian Seung
Sebastian Seung@SebastianSeung·
Flies are highly visual animals. That’s obvious to anyone who has ever tried to swat one. So it should be no surprise that eyes are so prominent on the fly head.
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Murthy Lab
Murthy Lab@MurthyLab·
By giving all #flyneuro labs access to the data when we began proofreading, science has proceeded alongside completion of the connectome. More papers highlighting the FlyWire resource coming soon … stay tuned!
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Murthy Lab
Murthy Lab@MurthyLab·
One quick teaser - @DudiFly and Kaiyu Wang identified nearly all sexually-dimorphic neurons brainwide - now possible to trace information flow for social communication and female-specific behaviors. Here is a subset of fru/dsx neurons (render from @alin1194):
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Murthy Lab
Murthy Lab@MurthyLab·
Excited to announce the completion of the first adult brain connectome - FlyWire is the neuronal wiring diagram of a Drosophila melanogaster brain with >130K neurons and >32M synapses. Explore at codex.flywire.ai. Check out the preprints:
Sven Dorkenwald@sdorkenw

We are releasing a whole-brain connectome of the fruit fly, including ~130k annotated neurons and tens of millions of typed synapses! Explore the connectome: codex.flywire.ai Reconstruction paper: biorxiv.org/content/10.110… Annotation paper: biorxiv.org/content/10.110… 1/6

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Murthy Lab
Murthy Lab@MurthyLab·
#flyneuro colleagues please share with your students. Michael Crickmore and @elliehoopla sent me their amazing students (thank you!) - @KyleThieringer is now off to do a PhD in neuroscience at @UW 🤩
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Pip Coen
Pip Coen@Pipcoen·
Excited to announce that I'm starting my group @ucl with @wellcometrust funding in 2023. We'll investigate audiovisual integration with the latest electrophysiology and optogenetic tools. DM me if you'd like to join as a postdoc, student, or tech. Or say hello at 329.23. #SfN2022
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FlyWire
FlyWire@FlyWireNews·
The fly central brain synthesizes sensory stimuli into decisions and actions. For the first time, ALL 46,944 branched and far-reaching neurons of both hemispheres of the central brain have been reconstructed and are available via FlyWire. join.flywire.ai
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Murthy Lab
Murthy Lab@MurthyLab·
Also excited to announce that @BenjoCowley is starting his own lab @CSHL in the Fall. If you want to work on neural network models of the brain, this is the lab to join!
Benjamin Cowley@BenjoCowley

Update of potential interest: I'll be starting a comp neuro group at Cold Spring Harbor Laboratory @CSHL in Sept 2022! Our group will build closed-loop machine learning techniques and interpretable, data-driven models to understand the step-by-step computations of the brain.

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Murthy Lab
Murthy Lab@MurthyLab·
So proud of @Christa_A_Baker - get in touch to do a postdoc in the Baker lab @NCState - Christa is a fabulous mentor, scientist and role model and her lab will be a trailblazer in solving the neural mechanisms underlying acoustic communication in flies.
Christa Baker@Christa_A_Baker

Excited to share that the Baker Lab will open in Biological Sciences @NCState Jan 2023! We will dissect the neural mechanisms underlying hearing in flies, and how those mechanisms are shaped by evolution. Will be recruiting at all levels so please reach out if interested.

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@DudiFly @alin1194 @elliehoopla @UW @PrincetonNeuro @ucl @wellcometrust @CurrentBiology