Brandon Law, M.D.

This case report describes the clinical course of a 32-year-old woman with anti-synthetase syndrome presenting with angioedema-like panniculitis and subsequently cutaneous ulcers, synovitis, and fevers, found to have a clonal TCR-beta gene rearrangement. ja.ma/4alsJqz

I only started my lab a little over 4y ago as an Instructor @harvardmed @MGHHeartHealth with a new K08 award in hand. 4 R01 awards as PI later, here's what I've learned as a physician-scientist:

"To find answers, @BalazsLab collaborated with a team that included the lead author of the @CellCellPress paper, @wilfredo_nk, a clinical pathology resident at @MGHPathology / @MassGeneralNews and a clinician-scientist fellow at the @ragoninstitute." 🌐: massgeneral.org/news/press-rel…

3D reconstruction of pancreatic cancer perineural invasion using CODA. Striking how cancer cells seem to be strangling the nerve at the point of invasion and extends both internally and externally along the nerve body. Made by Dr. @AshleyKiemen and underg. student Ann Jiang

Here is an animation showing a normal pancreatic tissue obtained using CODA, a method to produce 3D maps of large volumes of tissues and tumors. From serially cut H&E sections to digital volumes, spanning cm to micron length scales. More details here: biorxiv.org/content/10.110…