Alexander Kelly

Condensins are enriched at promoter regions in mitosis in many eukaryotes. So, does transcription factor into mitotic chromosome condensation? Check out our new work @elife doi.org/10.7554/eLife.…

@grewalsh Congrats everyone! 🍾

Stress controls epigenetic inheritance! A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance and cancer👉nature.com/articles/s4158…

It was wonderful to be part of the group honoring the memory and contributions of David Allis and Gary Felsenfeld to the field of chromatin biology and epigenetics at the National Cancer Institute. @theNCI Thanks to Shiv Grewal @grewalsh, and the organizing committee at NCI for putting this outstanding meeting together. @NIH @NUFeinbergMed @NorthwesternMed @LurieCancer @DrBrianStrahl @MuirLab @berger_lab @CKadoch @GAlmouzni @bernstein_lab @AsifaAkhtar1 @YiZhang_Lab @senergystic @todd_macfarlan @NogalesLab @pioneerfactors @PeterLewisLab @PlathLab @AlexKellyLab

Hurry! The deadline to register for the exciting symposium on "Histone Modifications and Chromosome Structures" is quickly approaching—this Friday, October 4, 2024. This symposium featuring talks by 25 renowned scientists is free to attend. To secure your spot, please visit: go.cancer.gov/hrxQPuE

🎉 Exciting Announcement! 🎉 “Histone Modifications and Chromatin Structure Symposium” 🗓️ Dates: October 17-18, 2024 📍 Location: National Institutes of Health, Bethesda, Maryland The NCI Center of Excellence in Chromosome Biology is delighted to invite you to our upcoming symposium. This symposium honors the legacies of Dr. C. David Allis and Dr. Gary Felsenfeld, pioneers in the study of chromatin and gene expression. Presentations from 25 renowned scientists. For more details and to register, visit: ncifrederick.cancer.gov/events/confere…

Happy to share our work about DNA supercoiling, an understudied physical feature of the double helix and the chromatin. 1/5 nature.com/articles/s4159…

📢ACCESS DENIED!! Ever wonder how heterochromatin causes transcriptional gene silencing and is epigenetically inherited? Excited to share our new story showing that histone deacetylation, a conserved feature of heterochromatin domains from yeast to mammals, limits access to SWI/SNF chromatin remodelers to prevent unraveling of nucleosomes, which enforces gene silencing and maintains high H3K9me3 density required for epigenetic inheritance #epigenetics #heterochromatin #histones #chromatin Congratulations to @rakesh_k_sahu and other lab members! cell.com/molecular-cell…

We're deeply saddened by the passing of Dr. Maxine Singer, esteemed scientist emeritus at NCI’s Laboratory of Biochemistry and Molecular Biology. Her groundbreaking work and dedication to science have left an enduring legacy. Our thoughts are with her family and colleagues🌹

Comprehensive cancer survivor care is essential. Learn more about the latest here:

@tim_bays @maggie162 wmata.com/fares/MobilePa…

@maggie162 Hmm it works similar to OMNY except for the whole “pay for the distance you’re traveling BS”

@stforth Congrats Scott!

I am delighted to share that I have been promoted to Associate Professor with tenure! I would like to thank everyone (lab members, students, colleagues, mentors, family, friends) who helped make this happen. I’m grateful to be able to keep doing science for years to come!

@mia_rosenfeld @iambic_ai Congrats Mia! 👍

absolutely STOKED to share that i'm starting as a machine learning drug discovery scientist @iambic_ai this week! molecular dynamics simulations + physics + machine learning + drug discovery = 🤩 p.s. i'm officially back in SD! @ my SD friends: let's grab a beer & catch up!!

@nussenza 😎Congrats Andre

2014 my mom Ruth was inducted into National Academy of Sciences. Who would have guessed history would repeat itself 10 yrs later. What an honor!

Preprint🚨on a new mechanism of genetic cheating in meiosis! 🧬We found that a mouse selfish DNA, R2d2, combines the elements of both male and female meiotic drivers! (gamete sabotaging in female meiosis) biorxiv.org/content/10.110…

My department is hiring! Tenure track faculty position in genetics. Researchers using any eukaryotic model, including fungi and plants are encouraged to apply! We are a broad biology department with strengths across all kingdoms. Join us! Apply by March 1 tinyurl.com/y4evds8p

Our department is looking for a computational biologist. Please help spread the word!

📢An elegant dance between replication and histone retention for epigenetic inheritance!🥳Our new work shows that heterochromatin domains are specialized replication zones that preserve parental modified histones to ensure self-templated chromatin assembly bit.ly/4b8wpNA

Now recruiting: enthusiastic postdocs to use advanced imaging methods to dissect biological processes. My group at Harvard has 2 Wellcome-funded positions examining the underlying mechanisms and resultant forces driving bacterial growth, division, and antimicrobial resistance.

Huge thanks to @chienlab @UMassBMB and @UMassMCB for hosting me at the MCB seminar series yesterday! @UMassAmherst has a great community and wonderful trainees, I really enjoyed all of my discussions!

@VidigalJoana @farmgirlphd @NatureSMB Really nice to see the Vidigal Lab's work highlighted like this!

Congratulations Joana and team!