Sandro Baldi

LIDAR sees the light! Please have a look at the latest (and my first as a postdoc) preprint from the Bonasio lab. Do you think there are RNAs out there that we haven’t cloned yet? You are not alone. biorxiv.org/content/10.110…

Huge congratulations to Peter. Well deserved!

We find no evidence that the formation of "transcriptional condensates" amplifies gene expression or increases transcription activation tinyurl.com/y56tof9c

@DanielKronauer Will there be a paperback version of the book soon? Looking forward to reading it

Speaking of ant castes... This is still the craziest example out there: the queen and worker of the African driver ant Dorylus molestus. Same genetic information, entirely different developmental outcomes. From Chapter 5 of my Army Ants book: amzn.com/067424155X

Exciting Cell paper from Hansen and Hendzel Labs!

"At its best, science is a self-correcting march toward greater knowledge for the betterment of humanity. At its worst, it is a self-interested pursuit of greater prestige at the cost of truth and rigor." hear, hear!

@TanentzapfLab Even worse and often used: „[PI name] showed“

It's commonly done, but I wish that instead of saying "[PI name]'s lab showed this" we'd try to say "person Y working in [PI name]'s lab showed this". In many big famous labs the PI can have minor input into the project. Important to give credit to those who actually do the work.

Nice reflection on the protein folding breakthrough. Even if you don't care too much about the technicalities, there are some intriguing thoughts about how science progresses inside and outside of academia in the last two paragraphs

@arnaud_kr @generegulation @cansnmzr @molina_lab Congratulations - love the graphical abstract

@TanentzapfLab You are not wrong, but the crux is to get a career (PI position) in the first place. Yes, I know many that got there without CNS papers, but it is an uphill battle.

I think it's imperative to tell young scientists that it is possible to have a wonderful successful career without ever publishing in Cell/Nature/Science, winning prestigious awards/fellowships, getting invited to give conference keynotes, or be elected to any academy or society.

We're hiring! Looking for a Lab Tech to join our new group at @embl Rome: embl.de/jobs/searchjob… Please share/RT! Thanks!

We have had encouraging discussions in our @IJMonod forum about prioritizing not-for-profit publishing, and not being enraptured by NPG and Elsevier for our labs and for our recruitment. If this is in line with your philosophy I encourage you to apply to join us!

@OdedRechavi This paper was later updated to include the Gabor citation 🙈

If you download the raw ChIP-seq data from a high profile paper there's usually about a 50% chance that it just looks like sonicated DNA. Mapped data from a Science paper today and there was just no enrichment anywhere. A giveaway is when there are no tracks shown in the paper.

@OMarshall_lab @SethCheetham Yes, that is also why the "complete story" scam works so well. You have genomics, behavior, cell biology et al. in the paper, and so each reviewer will be only proficient in one or two of the areas and you can get away with murder in the other ones

Out today - less than a week after the defence of my PhD thesis! We took a somewhat evolutionary perspective to talk about "unusual" flavors of H2A.Z remodelers. Check it out! authors.elsevier.com/c/1c5Lx3PA3sKj…

Please RT. We are recruiting a PostDoc to study epigenetic mechanisms. Cutting-edge methods to predict, observe, and manipulate epigenetic processes - Develop and execute the next breakthrough ideas. #epigenetics helmholtz-muenchen.de/fileadmin/IFE/….

Happy to start this week by sharing our new story showing that the transcriptional activity of the genome can be regulated by modulating the levels of pervasive histone modifications, such as H2AK119ub1, without the need for elaborate gene-specific targeting mechanisms 1/3

Beautiful work from the Barral lab out now!

@AnaBoskovic18 @NDescostes @ollie_rando Congratulations- very cool!

@NDescostes @ollie_rando Thank you Nicolas! I'm excited to be a part of the #EMBL community!!