Spivey Group

Enantioenriched spirocyclic azetidine oxindoles prepared using an SF5-containing chiral phase-transfer catalyst, reported in #OrgLett by @jamesabull, @ACSpiveyGroup, and coworkers @impchemistry. Check it out: pubs.acs.org/doi/10.1021/ac…

From alchemist to AI chemist nature.com/articles/s4157… A Comment article by @BeckyLGreenaway, @JelfsChem, @ACSpiveyGroup, & Sophia N. Yaliraki at @ImperialDigiFAB, @impchemistry on the use of AI when training future generations of chemists.

Very excited to make our latest group trip to #BSM2023 - so happy to see the meeting return, and with such a strong line-up of speakers!

Thanks @RWTH Aachen for a great new year symposium with @Schoenebeck_Lab @LeonoriLab @ACSpiveyGroup and thanks to our hosts / organising committee / ⁦@Bayer⁩

Scientists led by Bill Morandi @morandilab #LOC developed a simple method for converting the #indole group into other important structural elements. This facilitates the search for pharmaceutically active substances. Read more on: doi.org/10.1126/scienc… ethz.ch/en/news-and-ev…

For anyone at #MQSS2022 this week, our PhD student @josh_linfoot is presenting a poster at stand 8 - come say hi to find out about proteomics for insecticides! @maxquant

@stuartcantrill Loving this format

Directed evolution engineers an enzyme to catalyse the asymmetric alkylation of ketones - a nice read with some interesting mechanistic discussion from @francesarnold in @angew_chem: onlinelibrary.wiley.com/doi/epdf/10.10…

Great paper from the Balasubramanian group at @ChemCambridge in @NatureChemistry on probing the interactome of G-quadruplexes using co-binding-mediated protein profiling: nature.com/articles/s4155…

This morning we're talking about the novel idea of skeletal editing by N-atom deletion, discussing the interesting approaches from @group_levin at @UChiChemistry in @Nature (nature.com/articles/s4158…) and the Lu Group at Nanjing University in @angew_chem (onlinelibrary.wiley.com/doi/epdf/10.10…)!

AACR RESEARCH GRANT WINNERS ANNOUNCED! 🏆 Congratulations to Jerry Xiao and Stanislav Piletsky. Both winners are awarded $1000 towards their cancer research. Thank you to all who entered #cancerresearchgrant More info: ptglab.com/news/company-n…

Hot off the press! Check out our Mechanism of the Month piece on MIDA-Directed meta-Selective C-H Functionalizations in @TrendsChemistry - from @josh_linfoot and Alex Williams: authors.elsevier.com/a/1cmCR9CpcYOz…

New #PhD #studentship sponsored by AstraZeneca available in my group in collaboration with @BeckyLGreenaway and @ACSpiveyGroup on C–H functionalisation. Funding at UK levels. Interested candidates please get in contact by email.

Congratulations @HerzonLab for your total asymmetric synthesis of the Celastraceae natural product core euonyminol in @J_A_C_S. Super impressive! Look forward to seeing one of the cathedulin bis-macrocycles yielding to chemical synthesis soon. ACS pubs.acs.org/doi/10.1021/ja…

@Xavier_Morelli @CNRS @unilim @LievenMeerpoel @JanssenBelgium @institutpasteur (PLENARY - suite et fin) @ACSpiveyGroup @imperialcollege Dom Bonnet @unistra E. Saada-Bouzid #Nice @julie_broggi @IcrUmr7273

In this week's episode we're joined by @bauer_adriano (alumnus of the Arion group, Gentilucci and @ACSpiveyGroup, @MaulideLab and postdoc at @BaranLabReads) who takes us through his work on cyclopropanation by oxidative umpolung published in @angew_chem! youtu.be/wwuIT8CVQAs

Brønsted acid-catalysed enantioselective reactions that proceed through the non-classical 2-norbornyl carbocation - awesome paper from @ListLaboratory and co-workers at the Max Planck Institute in @NatureChemistry: nature.com/articles/s4155…

Individual resonances in overlapping multiplets can now be selectively excited in NOESY experiments using the rapid GEMSTONE approach, developed by Peter Kiraly, @ralphwadams and colleagues at @UoMChemistry in @angew_chem: onlinelibrary.wiley.com/doi/epdf/10.10…

A newly optimized iodoarene catalyst for the enantioselective synthesis of difluorinated alkyl bromides, with supporting computational studies - nice work from @JacobsenLab and colleagues at @HarvardCCB in @J_A_C_S: pubs.acs.org/doi/pdf/10.102…

Enjoyed yesterday’s #Collaboration2020 virtual event at @SyngentaUK featuring a poster from our very own Josh Linfoot - looking forward to an excellent day two!