Jason Mottern

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Jason Mottern

Jason Mottern

@AMotternStoic

INTJ; B.S. in Horticulture; Libertarian; U.S. Army veteran; Stoicism is the way.

Katılım Şubat 2026
558 Takip Edilen140 Takipçiler
Jason Mottern retweetledi
MAHA Action
MAHA Action@MAHA_Action·
RFK Jr. says the FDA’s war on peptides and other alternative medicines is over. “We’re gonna end the war at the FDA against alternative medicine.” “The war on stem cells, the war on chelating drugs, the war on peptides, the war on vitamins.” “The FDA has a job to do the science on these kind of issues.” “And then tell the public what they've learned from the science.” “But not tell people and not tell physicians what they can and cannot prescribe.”
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Dr. David
Dr. David@DrDavidivw·
The State of Florida is launching a study on Ivermectin to see if it can potentially cure cancer. This is HUGE.
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Jason Mottern retweetledi
peptidedaily
peptidedaily@peptidedaily_·
Final scorecard from the PCAC hearing: BPC-157 ✅ TB-500 ✅ KPV ✅ MOTS-c ✅ Epitalon ✅ Semax ✅ DSIP ❌ 6 of 7 peptides were recommended for the 503A compounding list. FDA staff went 0 for 6. Nothing changes at pharmacies tomorrow, formal rulemaking still needs to happen and could take 12-18 months. But the signal from this week is as clear as it gets. The peptide era in American medicine just officially started.
peptidedaily@peptidedaily_

EPITALON IS IN! The FDA advisory panel just voted 7-4 to recommend epitalon for legal compounding. Dr. Vladimir Khavinson spent 40 years developing this peptide for the Soviet military. 775 papers, 196 patents, and today it finally got recognized by an American panel. Khavinson would be proud. Emideltide (DSIP) did not pass unfortunately however. The first peptide they voted against.

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Afshine Emrani  MD FACC
Afshine Emrani MD FACC@afshineemrani·
I'm a cardiologist. Two of the cheapest amino acids on earth just did something in Baylor clinical trials that no expensive longevity drug has matched — and almost no physician is talking about it. Glycine and N-acetylcysteine. Together they're called GlyNAC. Both over the counter. Both pennies a dose. In aged mice, the combination extended lifespan by 24%. In older humans — in a randomized, double-blind, placebo-controlled trial at Baylor College of Medicine — 16 weeks of supplementation improved nearly every hallmark of aging at once: Glutathione restored toward youthful range. Oxidative stress and lipid peroxidation slashed. Mitochondrial function repaired — greater fat oxidation, better cellular energy. Insulin resistance improved. Inflammation down across IL-6, TNF-alpha, and hs-CRP — the exact markers I track in my heart patients. Endothelial function better. DNA damage and muscle breakdown reduced. Body fat down, strength up. And here's the line that stopped me: for some markers, older adults became statistically indistinguishable from young adults after 16 to 24 weeks. It wasn't just lab values, either. Cognitive scores improved. Processing speed and executive function improved. Exercise capacity improved. And gait speed improved — which matters more than most people realize, because walking speed is one of the strongest predictors of survival in older adults. One intervention. Nearly every system. The mechanism is elegant. Glutathione is your master antioxidant — it neutralizes free radicals, recycles vitamins C and E, protects your mitochondria, and detoxifies. Production collapses with age; older adults are reliably deficient. But the bottleneck isn't one ingredient. It's two. Glycine runs short and cysteine runs short. NAC alone doesn't fix the glycine gap. Glycine alone doesn't fix the cysteine gap. Supply both and the factory restarts. Sekhar's team calls it the "Power of 3" — glycine, cysteine, and the glutathione they build together. The trial doses were substantial: roughly 100 mg/kg/day of each. For a 70 kg adult, about 7 grams of glycine and 7 grams of NAC daily, split up. You can't reach that from food. Now the honest caveats, because this is where hype usually wins. The trials were small — dozens, not thousands. The strongest effects were in older adults with documented glutathione deficiency; a young, healthy person may see little. The lifespan data is in mice. And critically: stop taking it and the benefits fade within about 12 weeks. This is maintenance, not a cure. NAC can cause GI upset. If you're on nitrates or blood thinners, or have kidney disease, talk to your physician first. I take glycine daily and have written about it before. What the Baylor work changed for me is understanding that the pairing is the point — not either amino acid alone. If you're over 60 with fatigue, insulin resistance, or climbing inflammatory markers, this is a real conversation to have with your doctor. Two amino acids that cost pennies, with randomized human data, hitting mitochondria, inflammation, insulin, strength, and cognition simultaneously. We spend fortunes chasing exotic longevity molecules. Sometimes the answer is restarting a factory your body already built.
Afshine Emrani  MD FACC tweet media
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Jason Mottern retweetledi
Natalie Winters
Natalie Winters@nataliegwinters·
UPDATE: After exposing a Europe-based NGO for telling foreigners to donate millions to a Democratic voter mobilization operation to “change the outcome” of the 2026 midterms in the U.S. (at a cost of $94 per vote) the files and website were DELETED. Archived, of course. 😉
Natalie Winters tweet mediaNatalie Winters tweet media
Natalie Winters@nataliegwinters

🚨 EXCLUSIVE: I uncovered documents showing a Berlin-based network steering foreign donors toward a $19 million, Hillary-linked voter operation designed to “change the outcomes of national elections” and generate 200,000+ votes in key U.S. races. (Just $94 a vote!)

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Jason Mottern retweetledi
Real Peptides
Real Peptides@realpeptides·
FDA JUST APPROVED SEMAX. The FDA's advisory panel voted 8 to 5 to recommend it for legal compounding. BIG WIN!
Real Peptides tweet media
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Jesse Morse, M.D.
Jesse Morse, M.D.@DrJesseMorse·
🚨 The vote for Epithalon is in! Yes (7), No (4), Abstained (1) Overall conclusion = YES ✅ This vote will be considered by the full committee, FDA, and RFJ Jr.
Jesse Morse, M.D. tweet media
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Jason Mottern
Jason Mottern@AMotternStoic·
@GutFirstHealth @expertlivet I inject BPC-157 for overall health/ workout recovery. At 44, I’m not in my 20’s anymore, and the benefits for recovery, especially in my joints / muscle overuse have been amazing 🤩!
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Gut First
Gut First@GutFirstHealth·
@expertlivet Most people take oral these days, pinning has other valid uses of course but from what I've seen (maybe a perception bias) it's almost always for the gut
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Gut First
Gut First@GutFirstHealth·
Unpopular take but BPC-157 should be the LAST thing the FDA is approving, Instead all pharmacies should carry prescription grade betaine hcl + enzymes and prescribe regularly, Medical grade herbal bitters for bile flow, And Zinc L-Carnosine for gut lining. 80/20 of ALL of IBS, Sure BPC has it's place but if people were simply given these basics first they wouldn't suffer such intensive gut lining damage and microbial overgrowths where they have to reach for BPC. Can't you see it's just symptom managing that they're cashing in on, just because it's a peptide, Right compounds. Wrong intentions.
Polymarket@Polymarket

JUST IN: FDA advisory panel votes to expand pharmacy access to BPC-157, a peptide promoted for injury recovery and gut healing.

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Taya Bass
Taya Bass@travelingflying·
Best car: Tesla Best internet connection: Starlink Best social media app: X Best AI: Grok Elon Musk is the only person on Earth who can dominate cars, internet, space, AI, and social media at the same time.
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Jason Mottern retweetledi
Shira S , MD
Shira S , MD@RealSHIRA·
Der niederländische Anwalt, der Bill Gates, von der Leyen, Bourla, Schwab und Rutte wegen Bioterrorismus und Verbrechen gegen die Menschlichkeit angeklagt hat, wurde verhaftet – und sitzt jetzt in einem Hochsicherheitsknast. 🔥 Die globale Elite ist in Panik. Arno van Kessel, der die Zivilklage gegen die Architekten der Corona-Desaster anführte, wurde im Morgengrauen von einem Anti-Terror-Kommando aus dem Bett geholt – gefesselt, geknebelt, abgeführt. Kein Haftbefehl, keine Anklage, kein Kontakt zur Außenwelt. Einfach verschwunden. Weil er fast 200 Dokumente vorlegte, die den größten Verbrecherclub der Neuzeit entlarven. Die Angeklagten? Bill Gates. Ursula von der Leyen. Albert Bourla. Klaus Schwab. Mark Rutte. Sie alle wurden offiziell wegen Verschwörung, Bioterrorismus und Verbrechen gegen die Menschlichkeit benannt. Die Beweise liegen beim Gericht – aber der Kläger sitzt im Gefängnis. Das nennt man nicht Rechtsstaat. Das nennt man Vertuschung mit Handschellen. Die deutschen Medien? Sie schweigen. Keine Schlagzeile im Spiegel, keine Sondersendung in der Tagesschau, kein empörter Kommentar in der Zeit. Während die gesamte westliche Presse über jeden Furz von Elon Musk berichtet, ignorieren sie den größten Justizskandal seit Nürnberg. Warum? Weil die eigenen Leute auf der Anklagebank sitzen. Die Elite fürchtet sich vor der Wahrheit. Also sperrt sie den Boten ein. Aber die Akten sind raus. Und die Welt sieht zu. #ArnoVanKessel #BillGates #UrsulaVonDerLeyen #AlbertBourla #KlausSchwab #MarkRutte #Bioterrorismus #VerbrechenGegenDieMenschlichkeit #CoronaVertuschung #Systemversagen #MedienSchweigen
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Jason Mottern retweetledi
peptidepirate🏴‍☠️
peptidepirate🏴‍☠️@peptidepirate·
KPV the inflammation eraser ✏️ 🛡️✏️ 🛡️ ——————————————————— KPV might be the most underrated anti inflammatory peptide in the entire space🏴‍☠️ This is a 3 amino acid fragment of alpha MSH the natural hormone your body produces to regulate immune response and inflammation🏴‍☠️ The genius of KPV is that it kept all the anti inflammatory power of the parent hormone without any of the pigmentation effects or hormonal side effects🏴‍☠️ How it actually works🏴‍☠️ KPV inhibits NF-kB the master switch for inflammatory gene expression in your body🏴‍☠️ This is the same pathway that corticosteroids target but without suppressing your entire immune system🏴‍☠️ It reduces TNF alpha IL 6 and IL 1 beta the three cytokines driving most chronic inflammation🏴‍☠️ Where KPV crushes everything else🏴‍☠️ Gut healing leaky gut IBD ulcerative colitis Crohn’s it heals the intestinal barrier at the epithelial level🏴‍☠️ Combined with BPC-157 some amazing things can happen 🏴‍☠️ Skin conditions psoriasis eczema acne chronic wounds because it calms the inflammatory cascade at the source🏴‍☠️ Histamine intolerance and mast cell issues because it modulates the same immune pathways that drive these conditions🏴‍☠️ This works great for seasonal allergies one of the only things I’ve ever used that actually works 🏴‍☠️ Why it stands apart from steroids and NSAIDs🏴‍☠️ Corticosteroids suppress the entire immune system KPV modulates it back to balance🏴‍☠️ NSAIDs block one pathway and create downstream gut damage KPV heals the gut while reducing inflammation🏴‍☠️ KPV has antimicrobial properties on top of the anti-inflammatory action🏴‍☠️ No documented tolerance development across the research🏴‍☠️ The honest read🏴‍☠️ Human clinical research is still emerging most of the strongest data comes from animal models and mechanistic studies🏴‍☠️ But the safety profile and the targeted mechanism make it one of the cleanest anti inflammatory tools currently available🏴‍☠️ If your inflammation is gut driven autoimmune driven or skin driven KPV deserves a serious look🏴‍☠️ 🧬🔬
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Jason Mottern retweetledi
peptidepirate🏴‍☠️
peptidepirate🏴‍☠️@peptidepirate·
One of my personal favorites just got approved 🏴‍☠️ Peptides are the new frontier and can no longer be ignored 🏴‍☠️ Don’t sleep on KPV 🛡️
peptidepirate🏴‍☠️@peptidepirate

KPV the inflammation eraser ✏️ 🛡️✏️ 🛡️ ——————————————————— KPV might be the most underrated anti inflammatory peptide in the entire space🏴‍☠️ This is a 3 amino acid fragment of alpha MSH the natural hormone your body produces to regulate immune response and inflammation🏴‍☠️ The genius of KPV is that it kept all the anti inflammatory power of the parent hormone without any of the pigmentation effects or hormonal side effects🏴‍☠️ How it actually works🏴‍☠️ KPV inhibits NF-kB the master switch for inflammatory gene expression in your body🏴‍☠️ This is the same pathway that corticosteroids target but without suppressing your entire immune system🏴‍☠️ It reduces TNF alpha IL 6 and IL 1 beta the three cytokines driving most chronic inflammation🏴‍☠️ Where KPV crushes everything else🏴‍☠️ Gut healing leaky gut IBD ulcerative colitis Crohn’s it heals the intestinal barrier at the epithelial level🏴‍☠️ Combined with BPC-157 some amazing things can happen 🏴‍☠️ Skin conditions psoriasis eczema acne chronic wounds because it calms the inflammatory cascade at the source🏴‍☠️ Histamine intolerance and mast cell issues because it modulates the same immune pathways that drive these conditions🏴‍☠️ This works great for seasonal allergies one of the only things I’ve ever used that actually works 🏴‍☠️ Why it stands apart from steroids and NSAIDs🏴‍☠️ Corticosteroids suppress the entire immune system KPV modulates it back to balance🏴‍☠️ NSAIDs block one pathway and create downstream gut damage KPV heals the gut while reducing inflammation🏴‍☠️ KPV has antimicrobial properties on top of the anti-inflammatory action🏴‍☠️ No documented tolerance development across the research🏴‍☠️ The honest read🏴‍☠️ Human clinical research is still emerging most of the strongest data comes from animal models and mechanistic studies🏴‍☠️ But the safety profile and the targeted mechanism make it one of the cleanest anti inflammatory tools currently available🏴‍☠️ If your inflammation is gut driven autoimmune driven or skin driven KPV deserves a serious look🏴‍☠️ 🧬🔬

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Jason Mottern retweetledi
Real Peptides
Real Peptides@realpeptides·
What happens if you take some of the most popular peptides in the space, and put them all in one single vial? The KLOW blend (GHK-Cu + BPC-157 + TB-500 + KPV), explained: (1/14)
Real Peptides tweet media
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Real Peptides
Real Peptides@realpeptides·
Here's why these peptides are often stacked: BPC-157 → can help kickstart the repair process by boosting blood flow and aiding collagen-producing cells. TB-500 → can assist in getting repair cells to injured areas and promotes the growth of new blood vessels. GHK-Cu → can aid in rebuilding stronger tissue by ramping up collagen production and supporting tissue remodeling. KPV → may work to keep inflammation in check, creating a more favorable environment for healing. Each peptide seems to target a different aspect of the healing journey.
Real Peptides@realpeptides

What happens if you take some of the most popular peptides in the space, and put them all in one single vial? The KLOW blend (GHK-Cu + BPC-157 + TB-500 + KPV), explained: (1/14)

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Jason Mottern retweetledi
Peptide Base
Peptide Base@PeptideBase·
The scientist whose lab discovered MOTS-c just made the case for it directly to the FDA. Dr. Pinchas Cohen, Dean of the USC Leonard Davis School of Gerontology, highlighted: • MOTS-c is a naturally occurring mitochondrial peptide that his lab identified as a potent metabolic regulator. • In mouse studies, it improved insulin sensitivity, reduced liver-fat accumulation, protected against muscle loss and increased lifespan by 10% in older mice. • Cohen also discussed CB4211, a MOTS-c analog. He cited a Phase 1A study involving 65 healthy adults and a randomized Phase 1B study involving 23 people with obesity and prediabetes, in which he reported no evidence of drug-related side effects. • He cited approximately 250 published papers from more than 30 laboratories and said there was no evidence of a safety signal. His conclusion: moving current MOTS-c use from unregulated channels into quality-controlled, prescriber-supervised 503A compounding pathways represents the most patient-protective regulatory outcome.
Peptide Base@PeptideBase

Upcoming FDA peptide votes (EDT): Thursday, July 23: • KPV — 1:35 PM • TB-500 — 4:10 PM • MOTS-C — 6:00 PM Friday, July 24: • Emideltide (DSIP) — 10:45 AM • Epitalon — 12:50 PM Times are scheduled and may shift as the hearing progresses.

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Jason Mottern retweetledi
CryptoDaddi
CryptoDaddi@TheCryptoDaddi·
Peptides have been such a game changer for me personally: - Inflammation remains almost nonexistent with 1mg daily of BPC. - Down a significant amount on BF% so to GH peptides (started with Tesamorelin now currently on HGH). - With retatrutide my appetite remains under control consistently allowing me to hit calorie deficit and only eat what is beneficial for me. - My mitochondria is in good standing so the MOTS-c does really well for me during days I have intense workouts. Very happy that I found them. They have been an incredible addition to my lifestyle.
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Jason Mottern retweetledi
Jason Mottern retweetledi
Antonio Linares
Antonio Linares@alc2022·
the best article on peptides and the longevity explosion was written by a guy who called Palantir at $7. today an FDA panel voted to put BPC-157 on the compounding list — against the agency’s own staff recommendation. he’s been right before. he’s sharing this one for free.
Antonio Linares@alc2022

x.com/i/article/2034…

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