Alfonso Santos-López

If you like plasmids, insertion sequences, and bacterial evolution, you'll like this one! Now published in its fancy journal format. Thanks to everyone involved in the project, especially @SastreDJorge, @AlvSanMillan and the funders @BecariosFLC. nature.com/articles/s4155…

@EjercitoTierra @EjercitoTierra soy a uno de los que ayudó un mano Diego el lunes. Escribí esto en el país y le daba las gracias, pero no quise poner su nombre. ¿Podéis hacérselo llegar, por favor? Gracias. elpais.com/espana/madrid/…

¡Enhorabuena al soldado Diego Santillana Macías, del Regimiento de Infantería «Asturias» 31 #BrigadaGuadarramaXII, por su meritoria actuación durante el incendio en Tres Cantos!  🔸Junto a vecinos y agentes de la Guardia Civil, accedió a la zona de llamas para auxiliar a un hombre que había quedado atrapado intentando rescatar a sus caballos. Entraron en la finca abriéndose paso entre las llamas y localizaron al hombre gravemente herido. 🔸Improvisó una camilla y facilitó su evacuación hasta un helicóptero. Lamentablemente, el herido falleció al día siguiente. El Soldado Santillana continuó colaborando en las tareas de extinción hasta la madrugada, ¡Orgullosos de contar con los mejores en nuestras filas! #SomostuEjército 🇪🇸

Las vacas y el árbol milagro de los incendios de Tres Cantos: la historia tras la foto viral elpais.com/espana/madrid/… vía @el_pais

Habreis visto esta foto de las vacas de mi padre en muchos sitios con diferentes historias y mucha especulación -como en el tuit que cito-. Os cuento como se produjo este milagro en este artículo: elpais.com/espana/madrid/…

Our latest manuscript is out! Conjugative plasmids fuel AMR through IS-mediated gene inactivation, promoting the evolution of multidrug resistance in bacteria. Hope you like it

Excited to share our latest collab with Wenyuan Han's Lab! 🚨 Bacteria use dITP as an immune signal to activate NAD+-depleting effectors. Phages counter immunity by destroying dAMP (dITP precursor)! 💥🧬 Preprint 🔗: biorxiv.org/content/10.110…

Should I stay or should I go? 🎶 In a new opinion piece, @c_igler, Andrina Bernhard and I discuss how conjugative plasmids and temperate bacteriophages balance vertical and horizontal transmission: ecoevorxiv.org/repository/vie… Our framework illuminates many sides of MGE biology (1/7)

Happy to announce we have been awarded an i-LINK grant to create a new obligate intracellular bacteria consortium with 3 top labs @MattWelchLab @lamasonlab @bonazzilab. I can´t wait to start exploring new science with you all. See you soon at the @CNB_CSIC

Is it “winner-takes all” when the simplest living things compete? Check out my fresh publication on phage coexistence in Science and a thread below🧵 science.org/doi/10.1126/sc…

New paper from the lab. The brilliant @norapyenson led a multi-lab collaboration to investigate the consistent formation of stable phage communities infecting a single clonal host population. She explains the gist of it beautifully in the quoted thread. Congrats Nora et al

🚨New preprint!! How do antibiotic-resistant bacteria grow in the human gut microbiome, even without antibiotics? 🤔 We reveal strain-specific ecological interactions that shape their growth within microbial communities. 🧵👇 1/5 biorxiv.org/content/10.110…

» Gene acquisition by giant transposons primes eukaryotes for rapid evolution via horizontal gene transfer | Science Advances science.org/doi/full/10.11…

Las seis universidades públicas madrileñas han aprobado una Carta Abierta y un Comunicado para reclamar a la @ComunidadMadrid una financiación suficiente en los Presupuestos de 2025 en defensa del servicio público que prestan. uam.es #defendamoslaUniversidadPública @unicomplutense @uc3m @urjc @UAHes @La_UPM

Get ready to dance, our paper – Phage DisCo: targeted discovery of bacteriophages by co-culture – has been pre-printed! 🪩 This has been a really fun project to work on with @implosian, @baym, @nquinoneso, Kesther and Carmen! biorxiv.org/content/10.110… 1/

Awesome! Huge thanks to @evokerr, @livkosterlitz and Elisabeth Duan for this fantastic Spotlight on our recently published paper (nature.com/articles/s4155…).

Jose Luis Martinez—not active in social media ☹️—a legend of Spanish Microbiology will retire soon. His friends & colleagues will hold in Nov 28 a warm homage of a lifelong dedication to Microbiology & his many contributions to Ecology and Evolution of antibiotic resistance 👏

It is out @CurrentBiology ! we show that when learnt together conflicting experiences formed co-existing memories that compite to drive behavior & that ➕ valence of a stimulus is encoded differently in the 🧠 depending on its meaning.

For the past two years, we have been working on a novel approach to identify origins of transfer by conjugation in plasmids from any bacterial species. We are thrilled to see this work now published in @NatureMicrobiol after thorough peer review! nature.com/articles/s4156…

🧬🧬 𝙉𝙚𝙬 𝙋𝙧𝙚𝙥𝙧𝙞𝙣𝙩!!🧬🧬 Latest collab with the amazing Ming Li & Yue Feng labs! How do phages bypass multi-layered defenses in bacteria? Spoiler: with equally complex anti-defenses!! 🧵👇 biorxiv.org/content/10.110…

Extremely happy to see the final version of our paper "The expression of integron arrays is shaped by the translation rate of cassettes" out in @NatureComms 🥳!!! Thanks to the reviewers for their valuable feedback and suggestions! rdcu.be/dX8BB

Orgulloso y feliz de recibir el Premio de Investigación Margarita Salas de la CAM. Es el segundo premio en dos semanas ¡un verdadero reconocimiento al trabajo que hacemos en el labo! Gracias a mis mentores, compañeros y colaboradores ¡este premio es de todos! ¡Seguimos! 🍾🥂🎉