Becky Lamason
406 posts
@lamasonlab
Associate professor at MIT studying host-pathogen interactions
Proximity labeling of the Listeria monocytogenes surface reveals pathogen control of a host deubiquitinase biorxiv.org/content/10.648… #biorxiv_micrbio
Hybrid capture RNA-seq defines temporal gene expression in Rickettsia biorxiv.org/content/10.648… #biorxiv_micrbio
Host cyclophilin-mediated maturation of an obligate intracellular bacterial surface virulence factor biorxiv.org/content/10.110… #biorxiv_micrbio
Studying the pathogen R. parkeri, researchers in the Lamason Lab discovered the first evidence of extensive and stable interkingdom contacts between a pathogen and a eukaryotic organelle @JCellBiol news.mit.edu/2025/kingdoms-…
Acevedo-Sánchez et al. @lamasonlab @MITBiology characterize a novel interkingdom contact site between the ER and a cytosolic bacterial pathogen. They report that these bacteria–ER contacts (BERCs) require the tethering proteins VAPA and VAPB. hubs.la/Q031sGkq0 #Microbiology
Thrilled to share our latest preprint! Most of the Rickettsia secretome is a mystery, and 1st author Allen Sanderlin pioneered the use of BONCAT in this obligate intracellular pathogen to solve this problem, uncovering many new effectors largely unique to this pathogen.
A conserved interaction between the effector Sca4 and host endocytic machinery suggests additional roles for Sca4 during rickettsial ... biorxiv.org/cgi/content/sh… #biorxiv_micrbio
Thrilled to share our preprint on inducible expression and CRISPRi tools for Rickettsia from authors @jontmcginn, Annie Wen, @dbrinkley97, and Desmond Edwards! biorxiv.org/content/10.110…
