Önder Yildirim
946 posts

Önder Yildirim
@AlionderCPC
Director, Institute of Lung Health and Immunity (@LungHealthMUC) Researcher @HelmholtzMunich, Immunologist, COPD @Copd_Inet, Soccer fan, opinions are my own!












#WorldLungDay "Healthy Lungs, Healthy Life"🫁 This is the topic of the #WorldLungDay2025. It focuses on practical steps individuals can take and systemic changes needed for better respiratory care. At #HelmholtzMunich, researchers are paving the way for therapies of #LungDiseases. 💡One of the goals is to prevent and treat #COPD. Prof. Önder Yildirim and his team investigate why and how COPD progresses. 👨🔬 Önder Yildirim is Director of the Institute of Lung Health and Immunity at #HelmholtzMunich & founder of @copd_inet. 🎥 Watch the video and learn more about how to prevent and treat COPD! @AlionderCPC @copd_inet @LungHealthMUC #COPD2025 #LungHealth #COPDiNet





We have developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by tissue, organ by organ, at the cellular level in 3D. MouseMapper uncovered obesity-induced whole-neuronal changes, most notably, a loss of trigeminal nerve endings linked to impaired whisker sensitivity, as well as tissue-specific macrophage clustering across the body. Kaltenecker, Horvath, Al-Maskari, Kolabas, Chen… Ertürk, bioRxiv (2024) biorxiv.org/content/10.110…






1/n Happy to share our new single-cell+unsupervised AI drug discovery method is now published in Nature Biomedical Engineering!🚀 Huge thanks to @johnding86, @KaminskiMed and all collaborators. 🎉 We hope UNAGI can accelerate the discovery of new drugs. doi.org/10.1038/s41551…







A beautiful editorial by the great @FrancyPolverino and @meilan_han on why we need to study the airways of #COPD rather than the blood (which is useless in identifying biomarkers for COPD) bit.ly/3EvEwrX




