Dan Blears

17 posts

Dan Blears

Dan Blears

@BlearsDan

Transcription mechs and gene expression regulation enthusiast. UCL / Crick PhD student based at UCPH in the Svejstrup lab

Copenhagen, Denmark Katılım Ocak 2020
71 Takip Edilen54 Takipçiler
Dan Blears
Dan Blears@BlearsDan·
This massive box and 14 ice packs for 50ml of stripping solution? Crazy world @fishersci
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Tristan Croll
Tristan Croll@CrollTristan·
There's (quite rightly) a lot of raving about the new AlphaFold DB resource today. Thought I'd weigh in with my own example. DNA-dependent protein kinase catalytic subunit (uniprot.org/uniprot/P78527) is an enormous beast - a single chain of 4,128 residues! (1/10)
Protein Data Bank@PDBeurope

A number of scientists in the field of structural biology and bioinformatics have shared their ‘great expectations’ for the AlphaFold DB resource, including comments from Sameer Velankar, Gerard Kleywegt and others @embl: embl.org/news/science/a…

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Dan Blears
Dan Blears@BlearsDan·
@Li_Wan88: Scientific mentor, fellow consumer of Guinness and "unstoppable force of nature" in the words of JQ Svejstrup. Thanks for the support and opportunity to contribute to this awesome work on how cGAS senses translation stress. sciencedirect.com/science/articl…
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Matt Henderson
Matt Henderson@matthen2·
a large image of hundreds of flocking birds contains enough information to create an animation of a single bird flying
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Apoorva Baluapuri
Apoorva Baluapuri@Pol2Runner·
#EESGenomeInstability Jesper Svejstrup had recently summarized the challenges that Pol II overcomes during trancription in a beautiful review @NatRevMCB together with @MNoeGonzalez and @BlearsDan. Have a looksies: rdcu.be/ca3Xm
Apoorva Baluapuri@Pol2Runner

Jesper Svejstrup from @UCPH_health @uni_copenhagen @TheCrick starts out the second day of #EESGenomeInstability on a high note : consequences of DNA damage and heat shock on Pol II.

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Dan Blears
Dan Blears@BlearsDan·
Did the aquatic to terrestrial transition involve a fish growing arms and crawling out of sea? Well sure enough, Zebrafish have the capacity to develop arm-like structures. What about legs?
Cell@CellCellPress

Out now! Simple #genetic perturbation causes the formation of #limb-like bones in the pectoral fins of #zebrafish. These new bones integrate into #musculature, form joints, and articulate with neighboring elements bit.ly/2YGRw5E 🐟💪

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Roberta Migale
Roberta Migale@DrMigaleRoberta·
📢@TheCrick is officially a vaccination centre! This is our first week and it's been excellent! We've already vaccinated hundreds of healthcare/social workers & vulnerable people Well done to ~300 volunteers and the amazing @NHSuk @uclh staff helping us #CovidVaccine #vaccine 💙
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Oded Rechavi
Oded Rechavi@OdedRechavi·
BREAKING: President Biden signs an executive order banning validation of RNA-seq results with Real-time PCR
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Eric J Wagner
Eric J Wagner@Wagnerlab_RNA·
Unbelievable Achievement: Structure of the Integrator-PP2A complex reveals its CTD phosphatase activity is a general suppressor in transcriptional regulation!! science.sciencemag.org/content/370/65…
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Lea Haarup Gregersen
Lea Haarup Gregersen@GregersenLab·
Excellent review hot of the press by @MNoeGonzalez and @BlearsDan on stalling of RNA polymerase II 🧬 and its implications for transcription
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Keşfet

@isaac_fianu @dijiang319 @ScienceMagazine @fishersci @uni_copenhagen @Li_Wan88 @NatRevMCB @OdedRechavi