Boris Janssen

Example application of the model below! From work in progress investigating quantification of residual cancer burden as response assessment. In PREOPANC dataset. The mean residual cancer burden in these slides is 14.3 mm2. Now investigating how this correlates to survival.

❗️New paper❗️ The ISGPP team developed an AI model to segment residual cancer in PDAC post-neoadjuvant treatment: 528 patients, 14 centers Validated with 0.78 Dice score May enhance tumor response assessment 🖥️ Model: github.com/PHAIR-Consorti… 🔬 Paper: journals.lww.com/ajsp/fulltext/…

Interested in developing #SurgicalDataScience & endoscopic video analysis with #AI? Still in time to join the third Surgical Data Science Summer School @IHUStrasbourg, July 15-19, 2024! #Edu4SDS Application deadline April 15, 2024⏰ More info 👉edu4sds.org

@deniswirtz @UMichPath @WCMCPathology @AMPath @MDAndersonNews @Cornell @JHUPath @JohnsHopkins @WUSTL @DukeU Virtually infinite non-patient related training data; could be very useful for further AI model development!

One of these two H&E images is authentic, the other one is synthetic. QUESTION: Which one is synthetic? 1. The left image 2. The right image (This is a human pancreatic tissue) More about our new interpolation generative AI paper here: biorxiv.org/content/10.110…

🎄 Pancreas 2023 Wrapped! 🍾 🔟 October 2023: The use of radiomics 🤖 in pancreas surgery... future or present?! 🧐 Is radiomics already impacting your clinical practice? 🫵 This is the first tool to predict the risk of POPF 🐳

🎁 It's that time of the year... 🎄 Best of Pancreas Wrapped 2023!!!🍾 3⃣ March 2023: 🤖 The use of @ChatGPTapp and other large language models in surgical science 🧐 Did you change your practice in 2023?! If yes, how? CONTROVERSIAL TOPIC!

@deniswirtz @Stanford @Penn @Cornell @Caltech @JohnsHopkins @MIT @Harvard @Cambridge_Uni @UniofOxford @UCLA ❤️

Check out our new paper: "Three-dimensional assessments are necessary to determine the true spatial tissue composition of diseased tissues" In sum, 3D >>>2D. Read it here: biorxiv.org/content/10.110… About CODA: nature.com/articles/s4159…

Today in @NatRevGastroHep, review BRPC-LAPC #PancreaticCancer 📌 Preoperative chemotherapy & radiation 📌 A-B-C (re)staging & surgical decision-making 📌Clinical research agenda Great team effort 🇩🇪🇺🇸🇳🇱 nature.com/articles/s4157…

Now in @BjsOpen! Externally valid #radiomics pre-op fistula risk score (RAD-FRS) for Whipple! 🇮🇹🇳🇱 FIRST externally valid model ✅ Similar AUC (0.81) to (ua)FRS (0.79) in preop setting 📷 👏 @EwoutIngwersen, @JackieBereska and @PHAIRconsortium! academic.oup.com/bjsopen/articl…

The first ever Radiomics 👾 preoperative fistula risk score !!! Development 🇳🇱 and external validation 🇮🇹 🐳 The radiomics-based preop FRS performed similarly to the existing scores ( ROC 0.8) 💪 Great added value considering only CT derived data! academic.oup.com/bjsopen/articl…

Many thanks to Chris Wolfgang & @nyulangone pancreas team for hosting Dutch pancreas surgeons this week in The Big 🍏 for Dutch PREOPANC4 trial, implementing 🌎 best-practice for #LAPC in The Netherlands 🇳🇱 @DPCG_official. Joining great LAPC surgery and valuable discussions 🇺🇸.

Last week radiogist Håvard Bjørke Jenssen from 🇳🇴@Oslounivsykehus visited the 🇳🇱 @AmsterdamUMC HPB team! Sharing and aligning HPB CT segmentation ✍️ strategies with Yung Nio, @JackieBereska @i_verpalen and others! 📸 Visit finalized with the annual @AmsterdamUMC HPB BBQ!

This week 🇳🇱 @i_verpalen @JackieBereska etc. from @amsterdamumc visit 🇳🇴@AAFretland @knutjla in the @Oslounivsykehus! External validation of a CRLM CT segmentation model! 📸 Discussions on imaging-based response evaluation to neoadjuvant therapy in both liver and pancreas! 💉

Kick-starting the second edition of the #SurgicalDataScience Summer School at @IHUStrasbourg with a keynote on the "Evolution of Surgical Video Analysis" by our director Prof Nicolas Padoy @CammaLab! #EDU4SDS23 #MedTwitter #SoMe4Surgery #SurgicalAI

@1987Andrewk @Gio_Marchegiani @BJSurgery @BJSAcademy @young_bjs @des_winter @ksoreide @villesallinen @MarcBesselink @albe_balduzzi @PHAIRconsortium Not sure if I fully grasp your comment, but clinically, for this population, it would be very valuable to identify patients that are NOT at risk, or at low risk, of progression. These patients can then by discontinued from surveillance and avoid untimely or unwarranted surgery.

The future of IPMN management 🍇 will be based on two pillars 🏛️ Biomarkers and AI 🤖 Twelve AI based models to assess the risk of malignancy already exist! 😢 Methodological quality and reliability still to be improved… let’s work on it!! 🆓 read 👉academic.oup.com/bjs/advance-ar…

📢: @albe_balduzzi @BorisJanssen and @PHAIRconsortium in @BJSurgery 📈 12 imaging-based AI models to predict malignancy of IPMN 📊 Methodologically suboptimal 🔎 Methodologically robust prospective studies incl. non-surgical patients required! Read: academic.oup.com/bjs/advance-ar…

Can #AI based models predict the risk of #PancreaticCancer in #IPMN? ⬇️ Scoping review @BJSurgery @PHAIRconsortium open access link: doi.org/10.1093/bjs/zn… phair-consortium.com #alvleesklierkanker #SoMe4HPB

@EurPancClub #EPC2023 @BorisJanssen on behalf of @PHAIRconsortium! AI residual cancer burden (RCB) to evaluate impact of NAT in resected pancreatic cancer! RCB 🔬 NAT vs. upfront: 2.2 vs. 10.3 mm2 p<0.0001 Survival 📈 Above vs. below median RCB: 24 vs. 30 months. p=0.018