BJS

Presurgical levels of circulating tumour DNA in patients with resectable chemotherapy-naïve colorectal liver metastases: association with multiorgan recurrence and survival in the MIRACLE cohort ➡️ doi.org/10.1093/bjs/zn… 📊 In this cohort of 182 patients undergoing curative-intent treatment for CRLM, 19% were classified as ctDNA-high using the mFast-SeqS aneuploidy assay. ⚠️ ctDNA-high patients had markedly worse outcomes, with 1-year recurrence-free survival of 29% vs 52% and 3-year overall survival of 48% vs 78%. 🌍 Multiorgan recurrence within the first year was significantly more common in ctDNA-high patients. 🔍 The aneuploidy score independently predicted recurrence and survival on multivariable analysis. 🎯 mFast-SeqS may provide a low-cost, minimally invasive strategy to identify patients at high risk of rapid recurrence before treatment. Work by Lissa Wullaert , Lotte van Leeuwen , Vanja de Weerd , Mai Van , Esther Oomen-de Hoop , Jaco Kraan , Maurice P H M Jansen , John W M Martens , Dirk J Grünhagen , Henk M W Verheul , Cornelis Verhoef , Saskia M Wilting #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #some4hpb #some4tpl @DPCG_official @pancreatitis_nl @PancreasClub #PancreasClub2023 #PancreaticCancer #Pancreatitis #HCC @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe #PancreaticCancer #cholangiocarcinoma #HPBSurgery #GallbladderCancer #Oncology #LiverSurgery

Surgical innovation and technology ➡️ doi.org/10.1093/bjs/zn… The future of surgery will be more precise, personalized, and technology-enabled—but innovation must be judged by its impact on patient care, not by novelty alone This BJS Commission highlights how surgeons, engineers, scientists, and industry can work together to ensure new tools improve outcomes, equity, and value Work by @JBMatthews, Jelle P Ruurda , Peter G Vaughan-Shaw , Desmond C Winter , Andrew Beggs , Andrew Yiu , Brian Davidson , Barbara Seeliger , Chen Xin , Daniel Stoyanov , Daphne D Rietbergen , Fijs W B van Leeuwen , Gerlof M Kuiper , Guglielmo N Piozzi , Jianing Qiu , James M Kinross , João Ramalhinho , Jim S Khan , Kurinchi Gurusamy , Kyle Lam , Kai F Chan , Li Zhang , Matthew Boal , Matthew J Clarkson , Matthias N van Oosterom , Nader Francis , Neeraj Lal , Philip W Y Chiu , Tessa Buckle , Yafit Shasha , Israa F E Hussein #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #some4hpb #some4tpl @DPCG_official @pancreatitis_nl @PancreasClub #PancreasClub2023 #PancreaticCancer #Pancreatitis #HCC @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe #PancreaticCancer #cholangiocarcinoma #HPBSurgery #GallbladderCancer #Oncology #LiverSurgery #colorectalsurgery #StepUp4CRC @FightCRC @ACPGBI #ERAS @dice_europe #Crohn #proctology @Dukes_Club @ACPGBI_EduTrain @AECP_FAECP @PelvExGroup @escp_tweets @YouESCP #TeachMeColoproctology #Some4COLoprocto #some4UGI #uppergi #esophagealcancer #gastriccancer #reflux @ISDE_net @Augishealth @roux_group @T4UGIS @SARONG_Trial @YoungIFSO #bariatricsurgery

Surgical innovation and technology ➡️ doi.org/10.1093/bjs/zn… The future of surgery will be more precise, personalized, and technology-enabled—but innovation must be judged by its impact on patient care, not by novelty alone This BJS Commission highlights how surgeons, engineers, scientists, and industry can work together to ensure new tools improve outcomes, equity, and value Work by @JBMatthews, Jelle P Ruurda , Peter G Vaughan-Shaw , Desmond C Winter , Andrew Beggs , Andrew Yiu , Brian Davidson , Barbara Seeliger , Chen Xin , Daniel Stoyanov , Daphne D Rietbergen , Fijs W B van Leeuwen , Gerlof M Kuiper , Guglielmo N Piozzi , Jianing Qiu , James M Kinross , João Ramalhinho , Jim S Khan , Kurinchi Gurusamy , Kyle Lam , Kai F Chan , Li Zhang , Matthew Boal , Matthew J Clarkson , Matthias N van Oosterom , Nader Francis , Neeraj Lal , Philip W Y Chiu , Tessa Buckle , Yafit Shasha , Israa F E Hussein #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #some4hpb #some4tpl @DPCG_official @pancreatitis_nl @PancreasClub #PancreasClub2023 #PancreaticCancer #Pancreatitis #HCC @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe #PancreaticCancer #cholangiocarcinoma #HPBSurgery #GallbladderCancer #Oncology #LiverSurgery #colorectalsurgery #StepUp4CRC @FightCRC @ACPGBI #ERAS @dice_europe #Crohn #proctology @Dukes_Club @ACPGBI_EduTrain @AECP_FAECP @PelvExGroup @escp_tweets @YouESCP #TeachMeColoproctology #Some4COLoprocto #some4UGI #uppergi #esophagealcancer #gastriccancer #reflux @ISDE_net @Augishealth @roux_group @T4UGIS @SARONG_Trial @YoungIFSO #bariatricsurgery

Surgical innovation and technology ➡️ doi.org/10.1093/bjs/zn… The future of surgery will be more precise, personalized, and technology-enabled—but innovation must be judged by its impact on patient care, not by novelty alone This BJS Commission highlights how surgeons, engineers, scientists, and industry can work together to ensure new tools improve outcomes, equity, and value Work by @JBMatthews, Jelle P Ruurda , Peter G Vaughan-Shaw , Desmond C Winter , Andrew Beggs , Andrew Yiu , Brian Davidson , Barbara Seeliger , Chen Xin , Daniel Stoyanov , Daphne D Rietbergen , Fijs W B van Leeuwen , Gerlof M Kuiper , Guglielmo N Piozzi , Jianing Qiu , James M Kinross , João Ramalhinho , Jim S Khan , Kurinchi Gurusamy , Kyle Lam , Kai F Chan , Li Zhang , Matthew Boal , Matthew J Clarkson , Matthias N van Oosterom , Nader Francis , Neeraj Lal , Philip W Y Chiu , Tessa Buckle , Yafit Shasha , Israa F E Hussein #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #some4hpb #some4tpl @DPCG_official @pancreatitis_nl @PancreasClub #PancreasClub2023 #PancreaticCancer #Pancreatitis #HCC @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe #PancreaticCancer #cholangiocarcinoma #HPBSurgery #GallbladderCancer #Oncology #LiverSurgery #colorectalsurgery #StepUp4CRC @FightCRC @ACPGBI #ERAS @dice_europe #Crohn #proctology @Dukes_Club @ACPGBI_EduTrain @AECP_FAECP @PelvExGroup @escp_tweets @YouESCP #TeachMeColoproctology #Some4COLoprocto #some4UGI #uppergi #esophagealcancer #gastriccancer #reflux @ISDE_net @Augishealth @roux_group @T4UGIS @SARONG_Trial @YoungIFSO #bariatricsurgery

Standards for reporting research methods, interventions, and Outcomes in Surgical Prehabilitation studies (SOS-Prehab) ➡️doi.org/10.1093/bjs/zn… 🏋️ Prehabilitation trials need clearer and more consistent reporting to improve reproducibility and clinical implementation. 🌍 SOS-Prehab was developed through a two-round Delphi process with 53 international experts across exercise, nutrition, psychology, and perioperative care. 📋 The final checklist includes 40 items: 16 essential and 24 important reporting elements. 🔍 Key domains include intervention components, delivery methods, adherence, participant characteristics, and outcome measures. 📊 Used alongside CONSORT, SOS-Prehab may improve transparency, comparability, and evidence synthesis in prehabilitation research. 🎯 Better reporting can help accelerate translation of prehabilitation into clinical practice and policy. Work by Chelsia Gillis , Daniel I McIsaac , Daniel Santa Mina , Stéphanie Chevalier , Gabriele Baldini , Francesco Carli , Celena Scheede-Bergdahl , Linda Edgar , Vanessa Smrk , Leah Avery , Amal Bessissow , Miquel Coca Martinez , Robert Copeland , Susanne Oksbjerg Dalton , Gerad Danjoux , Linda Denehy , Dominique Engel , Chloe Grimmett , Michael P Grocott , Heather L Gill , Sandy Jack , Bente Thoft Jensen , Denny Levett , Graciela Martinez-Palli , Zoe Merchant , John Moore , Nicolò Pecorelli , Ian Randall , Bernhard Riedel , Geoff Schierbeck , Gerrit Slooter , Malcolm West , Julio F Fiore, Jr. , Collaborators #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #some4hpb #some4tpl @DPCG_official @pancreatitis_nl @PancreasClub #PancreasClub2023 #PancreaticCancer #Pancreatitis #HCC @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe #PancreaticCancer #cholangiocarcinoma #HPBSurgery #GallbladderCancer #Oncology #LiverSurgery #colorectalsurgery #StepUp4CRC @FightCRC @ACPGBI #ERAS @dice_europe #Crohn #proctology @Dukes_Club @ACPGBI_EduTrain @AECP_FAECP @PelvExGroup @escp_tweets @YouESCP #TeachMeColoproctology #Some4COLoprocto #some4UGI #uppergi #esophagealcancer #gastriccancer #reflux @ISDE_net @Augishealth @roux_group @T4UGIS @SARONG_Trial @YoungIFSO #bariatricsurgery @asgbi @ASiTofficial @eurohernias @SEIQuirurgica @ESCP_tweets @YouESCP

GLP-1 therapies, metabolic surgery, long-term obesity care — how should they work together? Our IFSO – BJS Academy Virtual Journal Club tackles one of the biggest questions in bariatric surgery, discussing the new international consensus guideline published in BJS. Missed it LIVE? The recording is now available. 🎥 Watch here: bjsacademy.com/bjs-academy/yo… @IfsoSecretariat #bariatric #surgery @BJSurgery

Clinical Outcomes Associated with Prior GLP-1 Exposure in Burned Patients ➡️doi.org/10.1093/bjs/zn…

Incredibly happy and proud to have received a grant from the @AECP_FAECP to launch our systematic review&Delphi study on recurrent diverticulitis! 🎉 Huge thanks to our amazing trainees, Andrea Taricani and Joaquín Mascaró, for all their behind-the-scenes work Let’s get started!

Development of a standard definition of ‘no-option’ and ‘poor-option’ for revascularization in chronic limb-threatening ischemia ➡️ doi.org/10.1093/bjs/zn… This consensus study established a structured, expert-validated definition of no option or poor option for revascularisation of patients with CLTI The multidomain ABRFC framework provides a foundation for standardized clinical assessment, trial design, and future guideline development Work by Mario Alejandro Fabiani , Jos C van den Berg , Oscar A De la Torre , Alfredo Verastegui , Anahita Dua On Behalf of , the International Cooperative Vascular Consortium (ICVC) #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #vascularsurgery #vascular #Ischemia @vascularsurgery

Diagnosis of inflammatory bowel disease after symptomatic faecalimmunochemical testing: population-based cohort study ➡️ doi.org/10.1093/bjs/zn… IBD is more common than CRC in patients aged <50 years referred on symptomatic FIT pathways using FIT ≥10 µg Hb/g In a selected cohort of dual-tested patients, FCP results provided additional risk stratification Incorporating routine FCP testing into symptomatic FIT pathways may better target further investigations. Work by James C K Ng , Alastair J Morton , Colin J Crooks , Joe West , Matthew J Grainge , Timothy R Card , David J Humes #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #colorectalsurgery #StepUp4CRC @FightCRC @ACPGBI #ERAS @dice_europe #Crohn #proctology @Dukes_Club @ACPGBI_EduTrain @AECP_FAECP @PelvExGroup @escp_tweets @YouESCP #TeachMeColoproctology #Some4COLoprocto

👏 Next up for BJS LIVE @evanscolorectal, joint Editor-in-Chief @BJSurgery @asgbi #asgbi2026

Clinical and molecular landscape of surgically resected early onset pancreatic cancer ➡️ doi.org/10.1093/bjs/zn… EOPC is associated with a shorter time to recurrence and more aggressive, adverse molecular pathology. Work by Stephan B Dreyer , Adam Bryce , Fieke Froeling , Shannon Jackson Australian Pancreatic Cancer Genome Initiative , Leonor Santana , Euan J Dickson , Maria Coats , Colin McKay , David Holroyd , Andrew V Biankin , Nigel B Jamieson , David K Chang #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #some4hpb #some4tpl @DPCG_official @pancreatitis_nl @PancreasClub #PancreasClub2023 #PancreaticCancer #Pancreatitis #HCC @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe #PancreaticCancer #cholangiocarcinoma #HPBSurgery #GallbladderCancer #Oncology #LiverSurgery

🔍 Explore the latest surgical research with our updated BJS Journals pages on BJS Academy. We now have dedicated pages for both BJS and BJS Open, featuring automatically updated tables of contents so you can easily browse the newest articles, reviews, and commentary as soon as they are published. 📖 Discover: • The latest issues and articles • World-leading surgical research • Open access content from BJS Open • Easy access to journal updates in one place Explore now: ➡️ bjsacademy.com/bjs-academy/ne… #LeadingSurgicalEducation #SurgicalResearch #MedEd #Surgery #OpenAccess @bjsurgery @bjsopen

Management of incidental gallbladder cancer in a nationwide CAPBIL study ➡️doi.org/10.1093/bjs/zn… 🟡 Incidental gallbladder cancer remains a challenging diagnosis, with 5-year DFS and OS of 41.5% and 45.1% in this UK multicentre cohort (n=285). 🔪 Patients undergoing liver resection had significantly improved outcomes, with median OS of 72 vs 26 months compared with no further surgery. 💊 Completion of adjuvant chemotherapy was also associated with better survival (OS 47 vs 26 months). 📊 Most resections involved segment 4B/5, highlighting current surgical practice patterns across UK centres. ⚠️ Advanced tumour stage (T3–T4) and nodal metastases independently predicted worse survival outcomes. 🎯 These findings reinforce the importance of aggressive multimodal management and careful pathological staging in incidental GBC. Work by the UK HPB Research Collaborative Group, United Kingdom #HPBSurgery #GallbladderCancer #Oncology #LiverSurgery #SurgicalOncology #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #some4hpb #some4tpl @DPCG_official @pancreatitis_nl @PancreasClub #PancreasClub2023 #PancreaticCancer #Pancreatitis #HCC @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe #PancreaticCancer

Clinical Outcomes Associated with Prior GLP-1 Exposure in Burned Patients ➡️doi.org/10.1093/bjs/zn… 💉 GLP-1 receptor agonists may offer benefits beyond glycaemic control in burn patients, with potential anti-inflammatory and immunomodulatory effects. 📊 In a large matched cohort (n=8,307 per group), prior GLP-1 use was associated with 54% lower mortality (OR 0.46; p<0.001). 🏥 Significant reductions were seen in ICU admission (−35%) and intubation (−62%), indicating lower critical care needs. 🦠 Infectious complications were also reduced, including sepsis (−32%), pneumonia (−24%), and MRSA (−27%), with less antibiotic use. ⚠️ A signal toward increased hypertrophic scarring (+27%) was observed at longer follow-up. 🎯 Prior GLP-1 exposure may improve burn outcomes, supporting further prospective studies to guide perioperative strategies. Work by Adam Boukind, MSE , Aviral C Sharma, BS , Marco J Henriquez, MD , Saif Badran, MD, PhD #Burns #CriticalCare #GLP1 #SurgicalOutcomes #Inflammation #PerioperativeCare #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #SoMe4Trauma #emgensurg @WSESurgery @NELANews

@BJSurgery The key is that in this randomized dataset BC specific survival outcomes are in line with earlier RCTs and show that these are eqiuvalent in terms of BC survival. Breast conservation has many of benefits overall, but better survival is not one of them.

Surgeon wellbeing isn’t optional — it’s essential. Missed our first Virtual Journal Club? Catch the discussion on: → Second victim syndrome → Resilience in surgery With trainee insights + expert debate. Watch the full session 👉 bjsacademy.com/bjs-academy/co… @BJSurgery @BjsOpen @young_bjs @TejedorPat @JJEarnshaw @robhinchliffe1 @GitaLingam @PVaughanShaw #surgery #journalclub

Sleeve gastrectomy versus Roux-en-Y-gastric bypass in patients with body mass index over 50 kg/m2: international multicentre cohort ➡️doi.org/10.1093/bjsope… This retrospective multicentre cohort study included 3978 patients after sleeve gastrectomy and Roux-en-Y-gastric bypass (RYGB) with initial body mass index > 50 kg/m2. The early and mid-term results (1 and 5 years) showed superiority for the RYGB regarding weight loss and sustainability. Diabetes remission rates did not differ. 👏👏👏Lars Kollmann , Ilan Rosenblum , Adisa Poljo , Pascal Probst , Markus K Muller , Piotr Kalinowski , Muhammed S Dalkılıç , Abdullah Şişik , Johanna Betzler , Mirko Otto , Stephanie Taha-Mehlitz , Beat P Müller , Daniel M Frey , Bassey Enodien , Emanuel Burri , Reinhard Stoll , Otto Kollmar , Robert Rosenberg , Florian Ponholzer , Johan Friso Lock , Sven Flemming , Erik Stenberg , Johan Ottosson , Ellen Andersson , Torsten Olbers , Ralph Peterli , Florian Seyfried , Anas Taha #SoMe4Surgery #MedTwitter #SurgEd #Surgery @BJSAcademy @BJSurgery #endocrine @IfsoSecretariat @YoungIFSO #bariatricsurgery #weightloss

Survival after breast-conserving surgery and radiotherapy versusmastectomy: propensity score analyses within a randomized anaesthesiology trial ➡️ doi.org/10.1093/bjs/zn… Breast-conserving surgery plus radiotherapy provides equivalent breast cancer–specific survival to mastectomy, with differences in overall survival likely reflecting patient selection rather than treatment effect. Work by Charlotta Wadsten , Anders Berglund , Emma Söderberg , Greger Nilsson , Leif Bergkvist , Mats Enlund , Fredrik Wärnberg #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #BreastCancerAwareness #BreastSurgery

Locoregional and systemic control after total neoadjuvant therapywith short-course radiotherapy for locally advanced rectal cancer: long-term outcomes from the LARCT-US study ➡️ doi.org/10.1093/bjs/zn… TNT with short-course radiotherapy followed by CAPOX/FOLFOX achieved excellent long-term local and distant control in high-risk rectal cancer, with particularly favourable outcomes in patients achieving complete response Work by Israa Imam , Per J Nilsson , Tanweera Khan , Eva Angenete , Bengt Glimelius #SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @evanscolorectal @robhinchliffe1 @bplwijn @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #colorectalsurgery #StepUp4CRC @FightCRC @ACPGBI #ERAS @dice_europe #Crohn #proctology @Dukes_Club @ACPGBI_EduTrain @AECP_FAECP @PelvExGroup @escp_tweets @YouESCP #TeachMeColoproctology #Some4COLoprocto