Brian Do

Clear and compelling interview with @baym on the harm of cutting funding to antibiotic research: wbur.org/news/2025/05/1… This affects so much of modern medicine; many cancer treatments, including regimens with curative intent, are only safe because of effective antibiotics.

Things I wish more people knew about doing science in the US (thread):

My lab at UCSF (hsiunglab.org) is looking to recruit multiple postdocs across the spectrum of wet/dry lab interests to contribute to our research in synthetic gene regulation, combinatorial genetics, and tissue biology (including liver biology and immuno-oncology). We esp. welcome individuals who add to our capabilities and perspectives in computation or specific biological domains in tissue biology. Where appropriate there would be exceptional opportunities to work collaboratively with the help of junior specialists in the lab, as well as with other UCSF labs with complementary expertise.

Are you a college student interested in MD-PhD training? Apply to the Harvard/MIT HEART MD-PhD Summer Program -- see below for more info! Apps due Feb 1st, 2025. #mdphd #doubledoc #physicianscientist

@TheSpenceLab @PeggyPHsu Congratulations @PeggyPHsu!! So excited to read this!

Excited to share our latest preprint: A spatially-resolved blueprint of the developing human lung reveals a WNT-driven niche for basal stem cells. biorxiv.org/content/10.110… Led by a talented team: @PeggyPHsu, Tristan Frum and Ansley Conchola - and with many other contributors!

The latest NYT poll writeup quotes the woman who was convicted of planting a severed finger in her Wendy's chili en.wikipedia.org/wiki/Anna_Ayala

We will not be lectured by extreme MAGA Republicans about democracy.

@amcdarnell @chidley_chris @Duke_PCB For all the trainees out there, if you are looking for a place to do rigorous, creative, and impactful science look no further!! @amcdarnell and @chidley_chris are two of the kindest, most thoughtful scientists I know -- congratulations on starting your independent labs!

Truly moved and delighted to announce that @chidley_chris and I will open labs this September at @Duke_PCB ! The Darnell lab will be delving deep into how amino acid limitation perturbs the ribosome at specific codons...

@SigmaAldrich Let’s get some HPLC grade chocolate @kaina_chen #SigmaAldrichChocolate

It’s World Chocolate Day, and we’re excited to announce that we’re giving away our famous Sigma-Aldrich chocolate bottles!

This young man spends his time making prosthetics for elephants. Humanity. 🌎❤️

"in that most prestigious of [academic] places, the overriding emotion was fear. Fear that grants wouldn’t be renewed, fear that work would be scooped, fear of failure." totalinternalreflectionblog.com/2024/06/16/fol… via @TIRscienceblog

Need to get this flag for my office

I am excited to share a part of my postdoctoral work that came out today in @Nature. We developed a single-cell nascent RNA sequencing method (scGRO-seq) that, among other applications, can help generate enhancer-gene maps. 🧵1/13 nature.com/articles/s4158…

@bloodgenes @harvardmed @DanaFarber @BostonChildrens @broadinstitute Congratulations Vijay!! So well deserved for one of the most thoughtful scientists and physicians I know!

20 years ago I was finishing my first year at @harvardmed... Never did I imagine I would be here today. Grateful to all the incredible lab members past and present, amazing mentors, remarkable colleagues, and others who have made this possible! 🙏 for all those who wrote letters!

Exciting to see what our discoveries have led to so far!! Lights a 🔥 under us, as well as many other physicians and scientists!

Now published @NatureCellBio📢 Using CRISPRi/a screening, we dive deep into the transporters driving essential nutrient import into cells. Discover more about amino acid transport, metabolism, ferroptosis, and environmental impacts on tumor growth here: rdcu.be/dErUO

How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…

This was ruled a foul in the final seconds of Samford-Kansas in a 1-point game.

We are profoundly grateful that Dr. Ruth Gottesman, Professor Emerita of Pediatrics at @EinsteinMed, has made a transformational gift to #MontefioreEinstein—the largest to any medical school in the country—that ensures no student has to pay tuition again. bit.ly/3wvBj7y