Cara Ellison

#TECPR1 replaces #ATG16 as receptor of the ATG5/ATG12 E3 ligase to conjugate #LC3 to damaged vesicles displaying sphingomyelin on their cytosolic face. New LC3 ligase for #autophagy and first ever receptor for sphingomyelin! Discovered by K.Boyle... embopress.org/doi/full/10.15…

Excited to share our most recent work on the giant ubiquitin ligase #BIRC6 out now in @ScienceMagazine science.org/doi/10.1126/sc…!   Thread below 🧵 (1/7)

What a friendly giant! Enormous ubiquitin ligase BIRC6 protects cells by inhibiting cell death enzymes. SMAC blocks BIRC6, driving timely cell death - So excited to share our work! @ScienceMagazine @Elliott_Lab_Ox @larissadi2 @BiochemOxford @LinacreCollege science.org/doi/10.1126/sc…

So excited to share latest work from @Elliott_Lab_Ox! We find BIRC6, an enormous #ubiquitin IAP ligase, directly inhibits caspases and we show how this is blocked by SMAC. biorxiv.org/content/10.110… Plus great mass spec collab with @adanpinto @kesslerlabox

@WandelMichal @EMBO_YIP @NAWA_Poland Congratulations Michal!

I’m grateful and honoured to receive trust and support from #IBB_PAS @EMBO_YIP @NAWA_Poland & #NCN_PL to start my lab at the Institute of Biochemistry and Biophysics Polish Academy of Sciences in Warsaw to research #HostMicrobeInteractions #newPI #EMBO_IG #NAWA_PolishReturns #NCN

@CaraEllison8 @CurrentBiology @FelixRandow @KukulskiWanda @CellBiol_MRCLMB Congratulations, Cara (and team)!

@CaraEllison8 @CurrentBiology @KukulskiWanda @CellBiol_MRCLMB Look who made it onto Twitter. And with a splash! Welcome, Cara.

@CaraEllison8 @CurrentBiology @FelixRandow @KukulskiWanda @CellBiol_MRCLMB Well done Cara!! Great to see you on twitter 😊

Delighted to share this research in @CurrentBiology! My thanks to @FelixRandow, @KukulskiWanda, Keith Boyle and Sean Munro @CellBiol_MRCLMB. Transbilayer Movement of Sphingomyelin Precedes Catastrophic Breakage of Enterobacteria-Containing Vacuoles cell.com/current-biolog…