Carolina Conte

20 posts

Carolina Conte

Carolina Conte

@CarolinaConte5

Katılım Mart 2019
44 Takip Edilen24 Takipçiler
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Carolina Conte retweetledi
Science Magazine
Science Magazine@ScienceMagazine·
A new Science study in mice provides insights into why females in their reproductive years appear to be relatively protected from chronic kidney disease, a leading public health concern. Learn more: scim.ag/3JO2DEC
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Paola Romagnani
Paola Romagnani@PRomagnani·
Preeclampsia from failed podocyte renewal leaves its mark across generations—compare newborn kidneys from normal vs. podocyte-deficient pregnancies. These colorful dots are nephrons science.org/doi/10.1126/sc…
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Paola Romagnani
Paola Romagnani@PRomagnani·
1/6: New paper: Sexual dimorphism in kidney disease and kidney adaptation to pregnancy are rooted in renal progenitor biology. science.org/doi/10.1126/sc…
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Paola Romagnani
Paola Romagnani@PRomagnani·
Our new study in Science is out! CKD progresses slower in females. 🔹Estrogens boost female renal progenitors to produce new podocytes for pregnancy adaptation. 🔹Loss of this mechanism causes preeclampsia, maternal CKD risk & fewer nephrons in offspring. science.org/doi/10.1126/sc…
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Paola Romagnani
Paola Romagnani@PRomagnani·
Look how much more important is to know if a patient is genetic or has anti-slit antibodies than if has MCD or FSGS at kidney biopsy. We have finally come to the era of autoimmune, genetic and adaptive podocytopathies. No more MCD or FSGS used as diagnosis!
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Paola Romagnani
Paola Romagnani@PRomagnani·
Our new study is out! By STED microscopy on kidney biopsy and ELISA assays we show 1/3 of pediatric and half of adult patients (more in primary FSGS) have autoantibodies against slit antigens different from nephrin. i.e. anti-slit Abs kidney-international.org/action/showPdf…
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Paola Romagnani
Paola Romagnani@PRomagnani·
A new study from our group demonstrates that tubular cell polyploidy protects from lethal AKI but promotes consequent CKD. Just published in Nature Communications nature.com/articles/s4146…
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Paola Romagnani
Paola Romagnani@PRomagnani·
What is a crescent? An abnormal response of renal progenitors while trying to replace lost podocytes. Our new study shows reversal of crescents into podocytes is anyway possible and changes disease outcome science.org/doi/10.1126/sc…
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Paola Romagnani
Paola Romagnani@PRomagnani·
Turning crescents into podocytes: the podocyte marker synaptopodin in purple and the renal progenitors in green. Our new study the cover story of Sci Transl Med this week science.org/doi/10.1126/sc…
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Paola Romagnani
Paola Romagnani@PRomagnani·
Our Nature Primer "Podocytopathies" is out! A shift in paradigm from patient stratification based on kidney biopsy findings towards personalized management based on clinical, morphological and genetic data is needed for these patients! nature.com/articles/s4157…
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Roberto Burioni
Roberto Burioni@RobertoBurioni·
La scienza ha migliorato la vita di tutti, anche quella dei cretini che grazie a internet (prodotto della scienza) hanno l’illusione di essere intelligenti #chetempochefa
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Roberto Burioni
Roberto Burioni@RobertoBurioni·
I sovversivi della scienza (a @LaStatale con Elena Cattaneo).
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