Giulia Antonelli

Our study "Piezo1, F-actin, and podcyte survival and regeneration" has been selected by the ASN editorial team for inclusion in their 2025 JASN-themed highlight edition. @MarEleMelica @PRomagnani @GiuAntonelli12 @AnnaPeired @ElenaLazzeri2 @letiziadechiara @CarolinaConte5

A new Science study in mice provides insights into why females in their reproductive years appear to be relatively protected from chronic kidney disease, a leading public health concern. Learn more: scim.ag/3JO2DEC

Preeclampsia from failed podocyte renewal leaves its mark across generations—compare newborn kidneys from normal vs. podocyte-deficient pregnancies. These colorful dots are nephrons science.org/doi/10.1126/sc…

Our new study in Science is out! CKD progresses slower in females. 🔹Estrogens boost female renal progenitors to produce new podocytes for pregnancy adaptation. 🔹Loss of this mechanism causes preeclampsia, maternal CKD risk & fewer nephrons in offspring. science.org/doi/10.1126/sc…

This study was a collaboration with @UNI_FIRENZE @LMU_Muenchen @hbellvitge @fondazionemeyer @AOUCareggi. Special thanks to Valentina Raglianti, Maria Lucia Angelotti, Letizia De Chiara, Marco Allinovi, Benedetta Mazzinghi for their key contributions! journals.lww.com/jasn/citation/…

Our new study is out! By STED microscopy on kidney biopsy and ELISA assays we show 1/3 of pediatric and half of adult patients (more in primary FSGS) have autoantibodies against slit antigens different from nephrin. i.e. anti-slit Abs kidney-international.org/action/showPdf…

Inhibitors of the renin-angiotensin system (RAS), SGLT-2, and the mineralocorticoid receptor (MR) were superior to dual RAS/SGLT2 blockade in attenuating CKD progression in a mouse model of Alport syndrome bit.ly/JASN0186 @hjanders_hans @RosKaroAT @cirluigi @LaBOORatory

Read our last commentary on genetic testing for kidney diseases! #nephrogenetics @UNI_FIRENZE @fondazionemeyer

Un team di ricerca internazionale, coordinato da @PRomagnani, docente #Unifi di Nefrologia, ha messo a punto una nuova terapia che previene lo sviluppo di malattia renale cronica legata al danno renale acuto Lo studio è su @NatureComms 👉 bit.ly/3rDWnTK #ricercaUnifi

A new study from our group demonstrates that tubular cell polyploidy protects from lethal AKI but promotes consequent CKD. Just published in Nature Communications nature.com/articles/s4146…

An amazing week at #EMBLSTED_MINFLUX course. Really glad to have joined in!!🔬

Turning crescents into podocytes: the podocyte marker synaptopodin in purple and the renal progenitors in green. Our new study the cover story of Sci Transl Med this week science.org/doi/10.1126/sc…

What is a crescent? An abnormal response of renal progenitors while trying to replace lost podocytes. Our new study shows reversal of crescents into podocytes is anyway possible and changes disease outcome science.org/doi/10.1126/sc…

Check out our new review on tubular cell cycle response upon AKI!!👇👇👇🧐🧐🧐@ElenaLazzeri2 @CarolinaConte5 @GiuAntonelli12

What is the impact of sex and gender on kidney cancer? Find out what clinical and experimental evidence reveal: mdpi.com/1268302 via @MDPIOpenAccess @PRomagnani @Ric_Campi @FrancescaBeche2 @CarolinaConte5 @AngelottiLucia @GiuAntonelli12 @ElenaLazzeri2

Honoured to be in the list and grateful to the @ERC_Research for supporting research on renal progenitors and kidney diseases #ERCAdG

Case Report: Collapsing Glomerulopathy as a Complication of Type I Interferon–Mediated Glomerulopathy in a Patient With RNASEH2B-Related Aicardi-Goutières Syndrome buff.ly/3tw7E7Q @FenaroliParide @AngelottiLucia @DelsanteMarco @PRomagnani #Glomerulopathy

Chronic kidney diseases generally arise from a disordered kidney filtration barrier within glomeruli. This review describes the roles of glomerular capillary pressure, the glomerular basement membrane, and podocytes in regulating glomerular filtration and permeability.

Which is the link between kidney injury and kidney cancer? The renal progenitor is crucial for kidney repair and is the cell of origin of several types of kidney cancers. Kidney cancer is an evolutionary trade-off to pay for kidney repair. In our KI review doi.org/10.1016/j.kint…

Cytoskeleton of a #podocyte as seen through a microscope: From widefield to #superresolution 3D-SIM to dSTORM. Acquired on our @zeiss_micro Elyra PS.1 #FluorescenceFriday