Ronald Chandler

We’re hiring a Postdoc in the Henderson Lab @ Van Andel Institute! Join our team studying neurodegenerative disease across scales (molecular → circuits). Flexible, high-impact projects and strong mentorship. Apply: vai.wd1.myworkdayjobs.com/en-US/VAICaree… Please share!

My lab at @Stanford is looking to hire postdocs for multiple projects on cancer biology and therapeutics. Our recent work has uncovered some truly remarkable mechanisms for cytotoxic small molecules and we're looking to build on this research. If interested, see below:

It's finally published, today in Lancet! The long-awaited outcome of the maraciclatide-enabled imaging of endometriosis by the dedicated Oxford team! Yes, you can see superficial lesions! And the activity aligns with lesion type, less signal in "white" lesions. Tour de force!

Online Now! An in vitro menstrual cycle using organoids captures epithelial cell transitions during menstruation and regeneration of the human endometrium dlvr.it/TSGWpK #stemcells

A null mutation in SERPINE1 protects against biological aging in humans science.org/doi/10.1126/sc…

Excited to share our new paper just out in Genome Biology. “A ternary-code DNA methylome atlas of mouse tissues”. Huge thanks to everyone who made this possible — especially @SolmoeLee, @KohliLab, and our wonderful collaborators across CHOP and Penn. doi.org/10.1186/s13059…

Capturing early TE stem cells. From Zhang Jian’s lab, “Mouse trophectoderm stem cells generated with morula signalling inducers capture an early trophectoderm state”, with a small contribution from us. #citeas" target="_blank" rel="nofollow noopener">nature.com/articles/s4155…

Establishment of chromatin architecture interplays with embryo hypertranscription nature.com/articles/s4158… #journals #feedly

PRC2 silences genes by adding H3K27me3 at the right spots in the genome. Our new work shows how the nucleic acid-binding domain (NBD) of SUZ12 keeps this activity under control, and what happens when you remove it.

@Jalberizo Congrats Jason!

Hey people, I finished my PhD! Thanks to my mentors, lab, and huge shoutout to mom & dad 🇳🇮!

The Jones lab is recruiting for a second opportunity @VAInstitute to study the metabolic underpinnings of autoimmune disease. Details and application portal here: vai.wd1.myworkdayjobs.com/en-US/VAICaree…

New study found that youth's narratives & perspectives on menarche are largely negative, linking to depression and anxiety, despite rises in menstrual activism. doi.org/10.1002/jad.70…

Our paper on deep single-cell DNA methylation analysis is out in Nature Communications rdcu.be/evfJm. Super elegant work by Nathan Spix describing replication dynamics, X-inactivation, and cell lineage identification.

New paper from our lab is out! Weight loss may provide temporary improvement in the phenotypic presentation of PCOS, but sustained lifestyle change may be required to maintain these benefits. doi.org/10.3390/nu1713…

We're hiring! Our lab at the Ragon Institute of MGB, MIT, and Harvard is looking for a motivated postdoc with experience in developing and applying deep learning models. You'll work at the intersection of spatial transcriptomics and structural biology. #postdoc

A neutralizing antibody targeting AMH receptor 2 (AMHR2) prevented and treated a PCOS like syndrome in mice cell.com/cell-metabolis…

AJOG Expert Review: Single-cell technology: the key to an improved understanding of the human endometrium in health and disease - Single-cell RNA-sequencing analysis: distinguishing the normal and tumorigenic endometrium ajog.org/article/S0002-…

Looking for a postdoc. Can start in August if you are interested. Thanks @SSRepro careers.ssr.org/c/job.cfm?site…

Was grateful to present my research at the Keystone Conference on Regenerative Biology of the Female Reproductive System, both an oral and poster presentation. Met some inspiring people in the field and acquired some great ideas for furthering my PhD research. #KSFemaleRegen25