Russell Jones

The Jones lab @VAInstitute is recruiting postdoctoral fellows interesting in studying how nutrition impacts anti-tumor immunity. vai.wd1.myworkdayjobs.com/en-US/VAICaree…

How exercise decreases the risk of cancer and cancer- related mortality by reducing immunosenescence and inflammaging sciencedirect.com/science/articl…

@Nature Commentary on diet caloric restriction vs cancer nature.com/articles/d4158… and importance of cancer metabolism statnews.com/2025/12/15/onc…

How a restricted diet (DR) improves the immune response to cancer and success of immunotherapy in the experimental model. T cell metabolic reprogramming @NatMetabolism nature.com/articles/s4225…

Top #Citations 2025: 5️⃣ @VishwaDeepDixi1et al (@YaleMed) show that cysteine depletion leads to adipose tissue browning and rapid weight loss in mice and humans. nature.com/articles/s4225…

New! Online now: Restricting lipid accumulation in tumor-infiltrating neutrophils mediates caloric restriction-induced anti-cancer effects dlvr.it/TPlGV5

Human gut M cells resemble dendritic cells and present gluten antigen @Nature @HansClevers nature.com/articles/s4158…

Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses go.nature.com/3YnywYB

Nice job @BrandonOswald3. And thanks to everyone who contributed to this study, including our great collaborators @eclien @Tcellogic @ketonemics and @krawczyklab. For more information, please read here: vai.org/article/study-… @VAInstitute

All in all, this work suggest that the anti-tumor effects of calorie restriction works in part by boosting anti-tumor T cell responses. Our study adds to the exciting new work out recently indicating that nutrition plays an important role in immunity against cancer.

Happy to share our latest paper from Dr. Brandon Oswald (@BrandonOswald3) showing that dietary restriction (DR) restricts tumor growth by stimulating anti-tumor T cell responses. @VAInstitute @VAIMetabolism nature.com/articles/s4225…

Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumor immunity and immunotherapy responses @NatMetabolism @DrRGJonesLab @VAInstitute nature.com/articles/s4225…

How it started How it’s going

Epigenetic scarring after chronic infection or cancer can lock immune cells into a dysfunctional state. Here, @Hazemghoneim11 & team @OhioState develop an in vitro model of terminal CD8+ T cell dysfunction that better mimics in vivo exhaustion. insight.jci.org/articles/view/…

#GLP1 medicines now address weight loss and other health conditions through innovative formulations and expanded indications, highlighting key questions about their efficacy and safety. ja.ma/4nHJMKw