Celine Chui HKU

Researchers from HKUMed have conducted a series of landmark studies demonstrating that statins can lower the risk of cardiovascular disease without increasing the incidence of major adverse events. hkumed.hk/8f720a

@Prof_IanWong @jackilau @jojoyyk @HaoLuo_UW @DorisSFYu @hku_son @hkumed @CSMPR_HKUPharm

Our study on repeated antibiotic prescribing in patients living with dementia. While we found no association with seizure or other neuropsychiatric disorders, repeated antibiotic courses were associated with an increased risk of all-cause hospitalization. nature.com/articles/s4151…

@VincentKCYan @Wanchun_Xu @yuta_taniguchi1 @ChuiCeline @FranciscoTTLai1 @snowly12191 @IwagamiMas85663 @Esther_CSMPRHKU @Prof_IanWong @hkumed @HKU_FMPC @HkuPharm @CSMPR_HKUPharm #HKU #HKUMed #FMPC #PrimaryCare #HKUPharm #CSMPR #MG #MyastheniaGravis #SelfControlledCaseSeries #SCCS #statin #risk

The team: @Boyuan_WANG_hku Dr Emily Tse @ChuiCeline @CindyLan897569 @hkumed @HKU_FMPC @HkuPharm @CSMPR_HKUPharm @hku_son #HKU #HKUMed #FMPC #PrimaryCare #HKUPharm #CSMPR #diabetes #T2DM #lipid #CVD #cardiocascular #TargetTrialEmulation

In our #multinational study in @JInternMed, #statin initiation may be associated with increased risk of incident #MyastheniaGravis #MG during the first 6–12 months, with a greater magnitude of risk elevation for higher intensity of statin therapy. onlinelibrary.wiley.com/doi/10.1111/jo…

From #HongKong #Chronic Disease Co-Care Pilot Scheme #CDCC participants, our team found that #smoking, physical inactivity, and lower educational level were significant associated factors for #preDM, Type 2 #diabetes #T2DM, and #hypertension #HT. rs.yiigle.com/cmaid/1662048

Our paper on @BMCMedicine provides an updated and comprehensive estimate of the #mortality and #morbidity burden associated with #smoking, using a 1.6 million cohort in Hong Kong. link.springer.com/article/10.118…

Shorter durations of #antibiotic prophylaxis, including no prophylaxis, appear noninferior to longer durations for preventing mortality in patients with #cirrhosis and upper gastrointestinal bleeding. ja.ma/44R9lS7

Our @AnnalsofIM paper found that #statins initiation associates with reductions of all-cause #mortality & #CVD in #T2DM adults, including low-risk groups. Results suggest statins initiation in T2DM adults even when short-term predicted CVD #risk is low. acpjournals.org/doi/10.7326/AN…

Delighted to share our latest study led by my PhD student @clairewei0830 examining the potential anticancer effect of valproate in bipolar disorder - our findings do not support this hypothesis despite promising signals from prvious preclinical studies bmcpsychiatry.biomedcentral.com/articles/10.11…

Our new study is out! We looked at anaemia treatments (ESAs) and fracture risk in CKD patients. Prolonged ESA use seems linked to a higher risk of osteoporotic fractures. This suggests we need to optimise treatment to balance benefits vs. risk. Full text: sciencedirect.com/science/articl…

Another study on AMR done using Hong Kong’s EHR

We’ve come a long way☺️ wrapping up my first GRF funded study with this great paper, amazing team!

Our new meta-analysis in Hypertension Research confirms Sacubitril/Valsartan effectively reduces both office and out-of-office blood pressure. This was a fantastic international collaboration with our colleagues at Chulalongkorn University. nature.com/articles/s4144…

Great to be part of this editorial discussing the threats of AMR and potential solutions in end of life care

Excited to share our latest study in @LancetRH_WPac : Psychotropic medication consumption increased globally after the onset of the COVID-19 pandemic, with variations in consumption patterns observed across different countries. @Esther_CSMPRHKU thelancet.com/journals/lanwp…

Antiseizure medications consumption in 73 countries and regions from 2... sciencedirect.com/science/articl… Our Aston U, HKU, UCL, WHO study shows that inequities in access to newer antiseizure drugs in developing countries where valproate used a lot. Good risk management is needed

Excited to share our latest study in @TheLancet: long-acting injectable antipsychotics (LAIAs) are more effective than oral and equally safe for older people, except for higher risk of EPS with typical LAIAs, but not with atypical LAIAs. @Esther_CSMPRHKU thelancet.com/journals/lanps…

Congrats to @Esther_CSMPRHKU and @WeiYLuna on this excellent work on LAIA for older adults in @TheLancet Psychiatry - more effective, equally safe despite extrapyramidal symptoms with 1st-generation agents (generally being replaced), not 2nd-generation! thelancet.com/journals/lanps…