

Caroline Cobine
178 posts

@CobineLab
Associate Prof., Physiology & Cell Biology, University of Nevada, Reno, School of Medicine. Studying gastrointestinal sphincter motility. All views my own.



🚨Fascinating study⏩#Enteric #Neuronal substrates underlying spontaneous & evoked neurogenic contractions in 🐭 colon‼️@AGA_CMGH @AmerGastroAssn🆕🔥 #ThomasGould @Sushmitaswarna0 @Emernib11 @CobineLab & colleagues @unrmed 🎉 🎯A large population of #nitrergic neurons of the middle colon shut their activity off just before contraction onset, whereas another population of nitrergic neurons initiated a response just after contraction onset👏 ✅Distinct neuronal activity patterns underlie specific stimuli⚡️ 🎯Nitrergic neurons but not NO is required for propagation of #CMMC✨ ⏬Dive into to learn more about💡Using cell-specific tools to image myenteric neurons of mouse colon & how the distinct subtypes are active during spontaneous neurogenic contractions🔥 🎯Offer a new tool to identify specific defects in motility in pathologic conditions that exhibit disrupted #motility🙌 👉 cmghjournal.org/article/S2352-… #ENS #ColonicMotility #DGBIs @AmCollegeGastro @my_ueg @ANMSociety @esnm_eu @INMAssociation @anma_i @ANGMA_AU @RomeGastroPsych @GutBrainScience @APSPhysiology @NYUPainResearch @NGMJournal @ajpgi @JNMjournal






New study by Karen Hannigan et al. reveals first evidence of direct & indirect coupling between #nitrergic neurons & ICC-IM subtypes in the internal anal sphincter. 📃ow.ly/eQjL50Tp39E 🎧ow.ly/rEI250Tp39J @CobineLab @dr._kisobella #motility #Gastrointestinal

The #SFGiants are excited to announce that Buster Posey will now take on a greater role as the new President of Baseball Operations




Meet Caroline Cobine, Ph.D., an associate professor in the Department of Physiology and Cell Biology @unevadareno! Her research is dedicated to understanding how the lower esophageal sphincter (LES) functions to prevent acid reflux. bit.ly/3B5t8B4 #UNRMed #PackPride

Happy Friday! New podcast 🚨! Join coauthor @CobineLab as she delves into the complex world of internal #AnalSphincterBiology on this week's episode of #GutGuts. Their research is shedding new light on smooth muscle cell function & neural pathways! 🎧ow.ly/h73J50Thv3Y

Congrats to our Class of 2024 Physician Assistants! 🎉 🎓 These @unevadareno PA graduates are ready to make a difference in health care in their communities. We are so incredibly proud of all that you have accomplished! #AHealthyNevada #NVGrad2024 #PackPride




I had a great time speaking about my research at the @physoc command and control of smooth muscle meeting in Dundalk Institute of Technology @SMRC_Lab !! Thanks to the organizers for a wonderful meeting and the chance to hear some amazing talks!
