Cole Lemasters

After Kiley was diagnosed with glioblastoma, an aggressive form of brain cancer, doctors told her she might have only months to live. At 18, she wrote a will, chose a casket, and began living scan to scan. But, over the next five years, she kept on living, defying expectations. Her scans stayed stable. Why? How? After a recent MRI, her husband @ColeLemasters used ChatGPT to help make sense of the dense language in her radiology report. That conversation led him back to Kiley’s original biopsy records, where ChatGPT helped surface a crucial detail: an IDH1 mutation. In partnership with her neuro-oncologist, he then confirmed what that meant. Under updated medical standards, Kiley’s tumor was not glioblastoma, but an IDH-mutant astrocytoma: still serious, but with a very different prognosis. Instead of bracing for the worst, Kiley and her doctors began focusing her treatment plan on long-term care. Now, after years of uncertainty, she and Cole are planning for a future.

@YannickBuccella @AkalStation @OpenAINewsroom This is exactly what happened, I uploaded original documentation from her biopsy in 2020 that just helped us identify that potential mutation and what the next plan was with her oncology team

I think it's pretty obvious how this went down, just as you said: they did her IDH1 status at the very beginning, because this was also standard back in 2020. Then this went into her file and when ChatGPT browsed her file with the knowledge of 2023/2024, it flagged the inconsistency between the diagnosis of glioblastoma and IDH1 mutant. Yes, they should have communicated the change of guidelines with her. My guess is that the IDH1 mutation went missing and she was just considered an exceptionally great course of a glioblastoma.

@AkalStation @OpenAINewsroom @Scobleizer This is exactly what happened! Didn’t change any of her treatment, but changed her outlook for sure!

This is something I can speak to personally. @ColeLemasters let’s connect. My wife has been living with astrocytoma for almost eight years now. There may be more to the story than the post shows, but IDH mutation status is one of the first things any major brain tumor center should test for. The fact that you found it rather than her care team is alarming. My guess is that she was classified as GBM under the 2016 WHO guidelines. The 2021 update reclassified these tumors based on molecular markers, so an IDH-mutant tumor called glioblastoma in 2016 would now be an IDH-mutant astrocytoma, grade 3 or 4. WHO essentially pulled IDH-mutant tumors out of the glioblastoma category because those patients tend to do better.

1st Team AC: INF Max Lemasters. Max was one of the leaders of our team and was consistent in the middle of our order. Max posted an insane .548 BA and a .628 OBP! Max stole 6 bases, scored 16 runs, and had 10 walks to just 1 strikeout. Congrats Max!

Dawg

Player of the Game 🏆 Liberty North puts up 14 runs in a big 14-10 win. Max Lemasters 2-3 | 1 RBI | 3 RS | 2B Consistent production at the plate and a key contributor in a high-scoring win. @LNEagleBaseball #YBM #YouthBaseballMidwest #PlayerOfTheGame #PostGame

Cole Lemasters used ChatGPT to reveal a false cancer diagnosis in his wife. “I won’t say that [it] saved her life,” he said. “But I believe God used it to save our future.” christianitytoday.com/2026/02/how-ch…

Committed‼️‼️ Thank you to everyone who supported me amongst my journey. @StateFairBSBL @jordan_dey5 @BallinBill98 @LNEagleBaseball @impactathletekc @JudKindle

@TarunAmasa @OpenAI Would love to try, invite please!

It’s official. We’ve raised $14m led by @OpenAI Startup Fund to bring AI to Excel. Endex is the first AI agent to live inside Excel. For the past year, we've been working with financial firms. Today we’re releasing it to the world. Our capacity is limited; comment below for an early invite 🧵

This is Blake Treinen. The Closer for the Los Angeles Dodgers. He went from having juvenile arthritis and borderline diabetes to throwing 100mph... Here's his behind the scenes story (that you need to hear):

@J16Faulkner MLB force feeding a NYY/LAD WS is evident.

Royals: Only score 3 runs in the most important 2 game stretch of the year. Also Royals: Win both of those games. How? Bullpen: 7.2 IP, 2 H, 8K, 3BB, 0ER Nails.

@AGreenberry19 Ignorant take.

This is soft!!! Dude doesn't win a ring one year and decides to call it quits!!! This guy's a you know what!!!

Sad to hear Stegall won’t be at the helm for these guys, but excited to know he will be spending more time with his family. Ryan was second to none in terms of his preparation and dedication to his players. Probably has his MU education to thank for that🐯. #MIZ #RFB

Big day for the kid @MaxLemasters1 😤

Don’t mind me as I faithfully watch the Royals continually dominate the month of February just to burn out in May, for they are 3-1 so far this young spring, so it appears the cycle shall continue. In a weird, paradoxical, way, hopefully the Royals suck over the next few weeks.

All-in-all, I have spent the last 2 hours combing through depressing data to prove the fact that almost every other team benefits from having great springs while this fact continually drags down baseball in KC. And thus, the meme proves true:

Behind the wind of another KC spring training win today, this meme understates yet explains entirely what I have dubbed the recent “Royals Hopeful ST Phenomenon” Embracing my inner @JayCuda with this analysis. An obscure account of recent Royals suckage, a thread🧵: