Dimitris Challoumas
59 posts

Dimitris Challoumas
@DChalloumas
Trauma & Orthopaedics West of Scotland, SCREDS Academic Clinical Lecturer University of Glasgow, Tendon Research
Glasgow, Scotland Katılım Nisan 2018
231 Takip Edilen233 Takipçiler

If you are a surgeon, anaesthetist, haematologist or physiotherapist involved in the perioperative care of haemophilic patients undergoing lower limb arthroplasty you'll want to read these clinical practice recommendations. @HaemoSocUK @haemophilia_jnl
onlinelibrary.wiley.com/doi/full/10.11…
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@KarimKhan_IMHA @BruknerKhan Thank you! It's truly an honour! Need to get my hands on those Brukner & Khan books ASAP!
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@DChalloumas Well done Dr Challoumas! Have been following your very relevant work for a long time as you know. k2 @BruknerKhan
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Largest systematic review and network meta-analysis to date on de Quervain's tenosynovitis and clinical practice recommendations based on the highest level of evidence available. Great team effort as always!
JAMA Network Open@JAMANetworkOpen
Managing de Quervain’s tenosynovitis in the clinic remains challenging. This systematic review and network meta-analysis recommends corticosteroid followed by immobilization as first-line treatment. ja.ma/478DbAk @dchalloumas @tendonglasgow @UofGSii
English
Dimitris Challoumas retweetledi

Dr. Millar @TendonGlasgow consistently captivates with his profound insights on translational science. An absolutely inspiring talk! @eors2023

Oporto, Portugal 🇵🇹 English
Dimitris Challoumas retweetledi

@moeed_akbar in action at #EORS2023 speaking about epigenetic signatures in soft tissue disease. Team effort by ourselves and @KieranWoolcock

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@GregLehman @jon_alessi @AdamMeakins @KThorborg @TendonGlasgow @Seth0Neill Which is exactly why living systematic reviews are important, because they keep updating their results, their strength of evidence, and practice recommendations based on newly-emerging evidence.
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@jon_alessi @AdamMeakins @KThorborg @DChalloumas @TendonGlasgow @Seth0Neill TBH, I don’t know if exercise’s results are amazing or not. It just seems like it hasn’t been tested appropriately so I think these strong recommendations are premature. We can certainly make a case to advocate for exercise based on other reasons
Toronto, Ontario 🇨🇦 English
Dimitris Challoumas retweetledi

The addition of PRP, steroid injections, acupuncture, shockwave, and another adjunct therapies does NOT significantly improve the effects of exercise on lower limb tendinopathies! Good work @DChalloumas @TendonGlasgow @Seth0Neill sportsmedicine-open.springeropen.com/articles/10.11…
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@GregLehman @jon_alessi @AdamMeakins @KThorborg @TendonGlasgow @Seth0Neill And this is because no other interventions (as monotherapies or with exercise) have produced results of strong enough evidence (i.e., moderate or high strength of evidence) to justify a clinical practice recommendation for their use. This may well come in the future though.
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@GregLehman @jon_alessi @AdamMeakins @KThorborg @TendonGlasgow @Seth0Neill We never said our recommendations are strong, please read the article. In fact we highlight a few times that the network results are based on low strength of evidence and we recommend exercise, which is safe, cost-effective and will help most people based on widespread evidence.

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Dimitris Challoumas retweetledi

V strong author team--first author @DChalloumas. Great timing for @BruknerKhan's Clinical Sports Medicine if the rumors are true. @rj_devos @pdkirwan @kgSilbernagel @ProfJillCook
Kudos @carlespedret @Seth0Neill @TendonGlasgow Gearoid Crosbie
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@GregLehman @AdamMeakins @KThorborg @TendonGlasgow @Seth0Neill Researchers choose to add other therapies to exercise and not vice versa, as the only intervention with a repeatedly proven track record is exercise. There is therefore no evidence to answer your question.
We are not saying it's the best, only that it should be tried first.
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@AdamMeakins @KThorborg @DChalloumas @TendonGlasgow @Seth0Neill So what? Did adding exercise improve results when added to other therapies. This doesn’t mean exercise is the best or only option. We just hold exercise to a far lower standard than other treatments. Hell, it didn’t even outperform acupuncture in one of their measures.
Toronto, Ontario 🇨🇦 English

@GregLehman @mgibsonphysio @RodWhiteley @carlespedret @Seth0Neill @TendonGlasgow We say conclusions on the effectiveness of these adjuncts "as monotherapies" cannot be made as they have predominantly been assessed alongside exercise in RCTs. That's why we recommend that they are all used with exercise, if exercise alone fails, and never as monotherapies.
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@mgibsonphysio @RodWhiteley @carlespedret @DChalloumas @Seth0Neill @TendonGlasgow For example, here they write that research is lacking so conclusions can’t be made. They then go on to give a conclusion/recommendation.

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Dimitris Challoumas retweetledi

And here we go again!!
Another big systematic review and network metaanalysis in Effectiveness of Exercise Treatments with or without Adjuncts for Common Lower Limb #tendinopathies
Kudos to the myths @DChalloumas
@Seth0Neill @TendonGlasgow
FREE FULL TEXT!
link.springer.com/article/10.118…
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@GregLehman @RodWhiteley @mgibsonphysio @carlespedret @Seth0Neill @TendonGlasgow Acupuncture ranked higher than exercise monotherapy as it performed slightly better but the difference was neither statistically nor clinically significant.
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@RodWhiteley @mgibsonphysio @carlespedret @DChalloumas @Seth0Neill @TendonGlasgow That’s not what it says though. It didn’t ask if exercise was the place to start. It asked if adding something to exercise alone is better. It also says here that acupuncture was better than exercise alone.


Springfield, Manitoba 🇨🇦 English
Dimitris Challoumas retweetledi

So this one was tough… but pulled together by @lindsaycrowe91 👏🎉
And a great team @moeed_akbar @rj_devos @pdkirwan @carlespedret @IainBMcInnes1 @StefanSiebert1 and King 👑 Kjaer !
sciencedirect.com/science/articl…

Glasgow, Scotland 🇬🇧 English
Dimitris Challoumas retweetledi

Absolutely delighted to get this published in the @BJSM_BMJ
We need better and more appropriate #PROMS for our #Achilles #Tendinopathy patients especially non sporting
Hopefully this can contribute
@richnorris00 @ProfJillCook @Jamie_Gaida et al
bjsm.bmj.com/content/early/…
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If you are involved in tendinopathy research you might find this useful. Many thanks to all co-authors and especially @TendonGlasgow
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Dimitris Challoumas retweetledi

I had the opportunity to be one of the reviewers of this great paper. Now, once published, I can highly recommend its lecture (and it's FREE FULL TEXT)
Neurogenic inflamation and #tendinopathy
@TendonGlasgow @DChalloumas88
pubmed.ncbi.nlm.nih.gov/36793930/
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