Donnacha Fitzgerald

100 companies started from an accelerator. 96% raise success rate. How much equity do they take? None. That’s 5050. No equity. No fees. No weird clauses. Applications open.

Announcing our 2026 Fellows! One is a neuroscientist exploring how the brain computes at a molecular level, another is a bioengineer 3D-printing human tissue. There’s a PhD student working on computational protein design, and an engineer developing robots to build large structures in space – just to name a few of the badasses in our new Fellowship cohort! With this one-year program, we want to support early-career talents advancing important science and tech. We connect them with senior scientists, invite them to our technical workshops, seminars, and Vision Weekends alongside leaders in their fields, and offer platforms for sharing their work. We are incredibly excited to introduce our 2026 Fellows! Longevity Biotechnology • Alex Plesa, Scientist, Harvard University @amplesa • Donnacha Fitzgerald, Founder, Origenity @DN_Fitzgerald • Gianluca Cidonio, Assistant Professor, Sapienza University @gianlucacidonio • Jakub Lála, PhD Student, Imperial College London @jakublala • Léo Lopez, Staff Scientist, Tufts University • Nick Schaum, Postdoc & Co-Founder, University of Cambridge & Covalent.Bio Neurotechnology • Avery Krieger, Founder & CEO, Constellation Systems @Biofall • Constanze Albrecht, Graduate Student, MIT Media Lab • Elisa Kallioniemi, Assistant Professor, New Jersey Institute of Technology • Max Kanwal, PhD Student, Stanford University • Sven Truckenbrodt, Group Leader, MRC Laboratory of Molecular Biology Secure AI • Huixin Zhan, Assistant Professor, New Mexico Tech • Keith Patarroyo, Research Fellow, University of Glasgow @KeithPatarroyo • Mateo Petel, Research Scientist, Stanford University • Tianyi Alex Qiu, Research Fellow, Oxford Human-Centered AI Lab @Tianyi_Alex_Qiu • Vivek Nair, CEO, Multifactor Nanotechnology • Alberto Privitera, Assistant Professor, University of Florence • Kathryn Shelley, Postdoctoral Researcher, University of Washington • Konlin Shen, Research and Development Engineer, University of California San Francisco • Qiancheng Xiong, Senior Scientist, A*STAR Bioprocessing Technology Institute Space • Philip Linden, Space Systems Engineer, Planet Labs PBC • Sidh Sikka, Co-Founder, Manifold Research @SikkaSidh Existential Hope • Abigail Olvera, Research Director, Golden Gate Institute for AI @Abi0lvera • Fin Moorhouse, Researcher, Forethought @finmoorhouse • Mahlaqua Mila Noor, Viral Immunologist, University of Cambridge • Ninon Lizé Masclef, Research Affiliate, MIT Media Lab @ninon_lize • Peggy Yin, PhD Student, Stanford University • Ruairidh Battleday, AI Researchers & Founder, Thinking About Thinking @RMBattleday Learn more about our Fellowship: foresight.org/engage/fellows…

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1/ Today we announce Pleiades, a series of epigenetic foundation models (90M→7B params) trained on 1.9T tokens of human methylation & genomic data. Pleiades accurately models epigenetics for genomic track prediction, generation & neurodegenerative disease detection from cfDNA, outperforming previous pure DNA baselines.

@Stanford_AI_Bio @JosephJacks_ @yusufroohani @arcinstitute Me too

@JosephJacks_ @yusufroohani @arcinstitute in dm

Following the amazing talk today by Emma Dann we are excited to host @yusufroohani of the @arcinstitute for a special seminar this Thursday @ 10AM, presenting the efforts towards a virtual cell platform🔮

🚨New paper🚨 Excited to share our latest on @Nature today: The PIVOT PENALTY in research. nature.com/articles/s4158… More than five years in the making. Key finding: The impact of new research steeply declines the further a researcher moves from their previous work.

It was awesome to join the @sequoia podcast with @josephinekchen and @gradypb to chat about modeling biology!

A special thanks to Giorgia Renne and Lucia Schmitz who were central to getting PROMETHEUS off the ground, Edith Heard, @JanKorbel5 and Alexander Aulehla for their early encouragement, Shreya Ghosh for initiating this article, and @EMBL for supporting this vision from the start.

We are seeking to bring bright minds together across key expertise to research and publish on several topics: scienceforimpact.org/projects/ Interested in any of these topics or have additional ideas? Reach out! scienceforimpact.org/get-involved/

I spoke with @EMBL about PROMETHEUS (Promotion of Ethics in Science), a new initiative to promote and optimize impact-driven science. Learn more about our mission and how you can be part of it at scienceforimpact.org

@embl Learn more about our mission and how you can be part of it at scienceforimpact.org

PROMETHEUS is an EMBL-born grassroots initiative to promote and optimise impact-driven science. We had a chat with Donnacha Fitzgerald, the intiative's founder and bridging postdoc at EMBL Heidelberg, to learn more about its aims and activities. embl.org/news/people-pe…

We are very happy to share our preprint (D. Lindenhofer et al.) of a high-throughput targeted scDNA-scRNA-seq (SDR-seq) method. Impactful for any application with a need to associate coding and non-coding variants to gene expression in tissue samples and cell culture systems.

How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…

Thrilled to share our new preprint. A thread 🧵 biorxiv.org/content/10.110…

Excited to be part of this project! It's a refreshing change from my usual routine, and I'm eager to see how the study results can empower young researchers in making informed career decisions. 🚀

1/12 We are excited to present #DEWSeq, a new analysis approach for identifying #protein–#RNA interactions from individual-nucleotide resolution sequencing that scales to large numbers of replicates to ensure reproducibility. #eCLIP #iCLIP #RBPs #NGS academic.oup.com/nar/advance-ar…

@K_Imkeller Thanks, Katharina!!🙏

Congratulations! Inspiring findings linking B cell biology and tumor heterogeneity.

@K_Imkeller We also see varying patterns of co-localization between T-cell subtypes and different B-cell maturation states across B-NHL entities (Fig. 5b), suggesting a relationship between tumor maturation states and T-cell response.

@DN_Fitzgerald So what's the role of the T cells in all of this? 🤓

[1/12] Thrilled to unveil our preprint on #bioRxiv in which a single-cell multi-omic and spatial atlas of nodal B-cell lymphomas (#BNHL) reveals the central role of differentiation in driving tumor variation and evolution: biorxiv.org/content/10.110…

@K_Imkeller Great question! In normal lymph nodes, germinal center B-cells must interact with follicular helper T-cells or dendritic cells to differentiate into memory or plasma states - our data support that these interactions are maintained in malignancy (Fig. 5 and Extended Data Fig. 11).

@AnnaMathioudak1 Thank you Anna!! I'm very grateful to have had the pleasure of working together 😊🙏

Plastic B cell maturation in nodal B-cell non-hodgkin lymphoma! An amazing preprint from a dear friend! Congrats @DN_Fitzgerald 🥳