Xinghong Dai Lab

Structural Mechanisms of SAMD9 Autoinhibition and Pathogenic Dysregulation biorxiv.org/content/10.648…

@HuiWang007 Congratulations! Beautiful work!

Here is the movie showing the hierarchical organization of the sheath layer, and how the giant sheath layer assembles from only one single SH protein.

Our paper is out! We resolved the sheath structure from M. Hungatei cells using cryoET. ⁦⁦Thanks to all the coauthors @zhou_lab⁩ and Gunsalus lab.⁦#TeamTomo nature.com/articles/s4146…

@ZhaozhuQ Congratulations Zhaozhu!

Thanks Rajini! It's a recognition for the excellent work of the past and present Qiu lab members. Also a great honor to be a Scholar named for Dr. Randall Reed, a pioneer in sensory biology/smell.

@yiweichang Congratulations Yi-Wei and team!

Very excited to share our latest study using cryo-ET to investigate actin filaments in #Apicomplexan parasites. This allowed us to learn where do these filaments originate at the cell tip and how they could be managed down the cell body to power motility! nature.com/articles/s4146…

@futianmin is one of the best speakers I’ve known. Looking forward to the talk!

@zhou_lab @ShihengLiu Feeling very proud as a @zhou_lab alumnus 🐮🐮🐮 Congratulations guys!

Check out our cryoEM result of mRNA editosome in Trypanosoma brucei! Awesome collaboration with Aphasizhev lab from Boston U. Many congrats to Bruce @ShihengLiu⁩ and other coauthors for another wonderful piece of work! science.org/doi/10.1126/sc…

@Millie23231 Run away and take a vocation!😉

We are excited to share NINJ1 structure and mechanism on BioRxiv that suggest NINJ1 dissolves membranes as a "Ninja" cookie cutter to complete lytic cell death. biorxiv.org/content/10.110… by Liron David and Bobby Hollingdworth @LironDavid2 @BobbyHollings

Happy to share our story on NINJ1, NINJ2 and plasma membrane rupture. The NINJ1 part has a similar structure but different perspective on the mechanism compared to what was published two weeks ago by the @HillerLab @Nature Stay tuned for a similar story from the @WuLabHarvard .