Hego Damask

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Hego Damask

Hego Damask

@DamaskCapital

Event Driven Special Sits at pod shop. Show me the incentive and I'll show you the outcome. NFA

London, England Katılım Ocak 2020
1.5K Takip Edilen226 Takipçiler
Hego Damask
Hego Damask@DamaskCapital·
@Longroaderstar After taking some more time to digest, probs more neutral than positive - this puts more weight on 4-year data and will definitely be a topic at AdCom given the potential readthrough to all Huntingtin-related treatments
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Hego Damask
Hego Damask@DamaskCapital·
@Longroaderstar Wondering why Bloomberg et al haven't picked up on this, should be material upside for $QURE
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Hego Damask
Hego Damask@DamaskCapital·
@jbulltard1 @dalibali2 There quite literally is a clutch pedal, even if it doesn't connect to the gearbox like in a normal manual. Koenigsegg did the exact same thing in the CC850 and people were frothing at the mouth for it. Convenience of an auto in cities with manual feel for mountain roads is a win
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jbulltard
jbulltard@jbulltard1·
The path we're headed down is scary. First it was all the nerds wanting self driving cars, then ferrari released a $700k electric car that looks like a box in April followed by yesterday's fake manual transmission reveal. We're headed in the wrong direction as a society folks.
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Hego Damask
Hego Damask@DamaskCapital·
It's a novel ITK inhibition mechanism, which is always going to be met with some caution at first, even if preclinical safety data is v strong. Prescribers likely will want more real world safety data before prescribing in 1L. Likewise, there's going to be so much existing competition in AD ($KYMR, $NKTR, generic Dupi, et al) at launch; seems far more realistic to underwrite 20%+ in 2L than tangible market share in 1L, at least for now. But who knows, on paper it definitely fits the efficacy benchmarks for 1L in my view.
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Hego Damask
Hego Damask@DamaskCapital·
Someone tell me why $CRVS isn't strong R/R at these levels (<$15/sh). Yes, they'll likely be 2L only in AD, but that's still a 3bn+ dollar opportunity, and at least 1bn risk-adjusted in the US alone. Rare that a biotech with data this promising trades at/below 1x risk-adjusted peak sales. Thoughts @A_May_MD @seedy19tron ?
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Hego Damask
Hego Damask@DamaskCapital·
That's what I'm getting - it seems like there's tangible optionality on top of the 2L AD story, but even if you discount EVERYTHING other than 2L in AD and apply a <30% PoS, that alone should represent triple-digit upside from current levels. What am I missing that the market is pricing in? Overdone competitive fear from $KYMR? Preference towards $NKTR in 2L? Overall concerns on data presentation and subsequent applicability to Ph3? Safety?
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pm@pmill145·
@DamaskCapital $crvs will be much more than "2L only in AD" (say people much more knowledgeable than me.)
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Hego Damask
Hego Damask@DamaskCapital·
"It's supposed to be hard. If it were easy, everyone would do it." - Jimmy Dugan
Brett Caughran@FundamentEdge

It is easy as a stock picker to blame the external environment. "My portfolio sucks because the market is all about AI and retail flows". I had an experience with this early in my career that stuck with me. The investment team was bemoaning the macro driven market (this was '08/'09), citing high correlations as a challenge to L/S spread generation. The head of the fund responded with a table of realized stock price dispersion, "our job is to, ex-ante, identify the winners and the losers...and I don't know about you, but I see a lot of spread potential in this analysis". The message was clear: winners don't complain, they figure it out. This was a clear pattern I saw in the best PMs I worked with over my career. They didn't complain, they just figured it out. The job of a L/S PM is to find spread between longs & shorts, wherever it is. They adapted to the market environment when necessary. I saw this in real time when I was a PM at a large multi-manager. Sure, great PMs would have drawdowns as market conditions would change, but they were flexible when needed, flowing with the market regime to make money in new ways. Sort of the antithesis of the calcified value investor "I have one way of making money, buying cheap assets, and I'll go to my grave doing so". And even in this AI & retail driven tape, there is plenty of evidence of dispersion. In my healthcare coverage of 152 names, 75 of them have of them have hit threshold returns this year (longs up over 25% and shorts down over 15%), only halfway through the year. A few of these are AI-influenced, but the vast majority are idiosyncratic and business/industry driven moves that could have been identified with the right research (of course, it's always clear in hindsight). There is plenty of spread potential in this tape, you just have to find it. (Caveat: it's insanely hard. But it should be, as the rewards to consistently generating 5%+ long/short spread in equities are immense. And I fully grasp that I am shouting this message from the sidelines, not "in the arena", so evaluate this message as such)

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Hego Damask
Hego Damask@DamaskCapital·
@unemon1 Do you have a view on the company now? Turnaround still ongoing but at sub 2bn mkt cap should be becoming interesting to strategics...
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unemon
unemon@unemon1·
SHORT $SONO - we now see sales growth decelerating sharply and don’t buy into management’s guidance… gear up for a sharp rerating of the stock price very soon unemon.com/ResearchEasy/2…
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canoebrookbl
canoebrookbl@canoebrookbl·
$abvx, $prax, $rvmd, $celc, $cogt, $nktr all still have significant downside risks from current levels. Timing within 3-6 m. Target >30-50% down.
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Hego Damask
Hego Damask@DamaskCapital·
@ACapitalLP Smaller market caps you can have an edge, even if technical - take $PPGN, many of the larger event driven funds can't get into for fear of liquidity headwinds. The work needs to be done either way - and per John le Carré, a desk is a dangerous place from which to view the world!
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Hego Damask
Hego Damask@DamaskCapital·
@ACapitalLP Pareto principle - 80% of returns will be made by 20% of positions, and of those 20% it'll be 80% made by 20% within that. With that said, for special sits absolutely better to know fewer stone cold. Can turn in a heartbeat (look at $ABVX or $IP) and you can play both ways.
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Hego Damask
Hego Damask@DamaskCapital·
@taobanker Thoughts on whether recent selloff could pose a good entry opportunity? Market seems to be pricing in c.5% FCF growth over next 5 years when biz should be able to do 7%+ even after assuming c.10% volume decline for FY26E
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taobanker
taobanker@taobanker·
$JFN ... decent argument to be made that this is the best bond alternative in the equity market... the reliability of their earnings growth has been incredible. trading at 8%+ earnings yield
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Hego Damask
Hego Damask@DamaskCapital·
@orrdavid Seems like you’re getting a good chunk of these ($JFN especially) killed by tourism and cost of energy factor exposure, both of which are derivatives of Hormuz. If you believe that Hormuz will resolve imminently and concretely, seems like a good time to add size.
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David Orr
David Orr@orrdavid·
I've been reviewing what's been going wrong for me since March 1st in the hedge fund. I'm personally in a 20% drawdown (-15% after fees), which is particularly bad for me. Usually during tough periods it's my short book causing problems. This time it's not. My shorts are only losing me 11% since then, while I have been 165% gross short and the Russell 2000 (best proxy for my short book) is up 9%. Gross adjusted, my shorts should be down 15%. Plus, my shorts run higher beta so really they should be down 20%. So alpha on shorts has actually been strong. The market did go up real fast, so of course I lost a lot, but I still consider this a big victory. It's the long book where I am getting *killed*. This is so different from past junk meltups. Stocks like $9022, JR Central who's main asset is the famous Shinkansen that links Tokyo with Nagoya, Kyoto and Osaka. This is one of my big losers. This trades for 7x earnings with solid earnings growth.
David Orr tweet media
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Hego Damask
Hego Damask@DamaskCapital·
@alixpasquet Incredible that this stuff is free. You're absolutely one of the greats, can't wait to see what the next decades hold for Prime Macaya.
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Hego Damask
Hego Damask@DamaskCapital·
@alixpasquet you mentioned your memo on barriers to scale - would love to read, if at all possible. Thanks in advance, as always an inspiration.
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Brett Caughran
Brett Caughran@FundamentEdge·
As a junior analyst, do not, and I repeat *do not* use AI to write an investment thesis. Particularly if you are using said thesis to try to get a job. Your job is to use AI to find creative ways to go incredibly deep on the key drivers of a business with AI, then create rigorous due diligence tracking systems for the key drivers. And FOR SURE highlight that work as part of your pitch. You are trying to highlight the tool as something that deepens insight formation on the business and the stock, not something that took a 40 hour process down to 2 hours and produced AI Slop. For so many PMs, this will be an automatic ding. Create a “pitch pushback” agent to find logical gaps, anticipate questions, and get suggestions on coherent idea flow. But the final product should be something that is 100% produced by hand.
Gregory Blotnick@gregoryblotnick

there is a gap between intention and perception probably 20 times now I have looked at a stock pitch or similar and replied w some version of: “this looks like an LLM did it. You may have done the entire thing by hand, the long way, whether u did or not is none of my business. But someone u send this to - someone who actually matters - is going to have the same reaction I did. And that ain’t gonna be good for ya. Do with this information what u will.” ur intentions don’t matter u have to mentally bridge the gap over to the other person’s perception and say “how will this appear to them when they first see it” this dynamic will only become more prevalent as robots create all this shit, and I guarantee it is not limited to stock pitches, it goes for ALL work product “but I had good intentions” isn’t enough….world don’t work like that…go the extra step.

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Hego Damask
Hego Damask@DamaskCapital·
@alixpasquet Very much looking forward. Will there be a recording for us EMEA folks?
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Alix Pasquet
Alix Pasquet@alixpasquet·
Will do an AMA tonight at 7pm. Will talk about a few topics on my mind and take questions. Any investment and self development questions welcome! @alixpasquet9198" target="_blank" rel="nofollow noopener">youtube.com/@alixpasquet91
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Joshua Kushner
Joshua Kushner@JoshuaKushner·
Today we announce Thrive Eternal, a permanent capital holding company that will be concentrated in a small number of assets that we can own and steward over many decades. Across Thrive Capital and Thrive Holdings, we are building and investing through a moment of exponential change; backing emerging technologies, the infrastructure that powers them, and the businesses they can transform. Increasingly, we see a fourth category. These are assets with qualities that cannot be replicated by technology. Iconic franchises and cultural institutions rooted in tradition, identity, and shared experience. In a world shaped by abundant intelligence where creation scales and distribution fragments, we believe they will matter even more. Thrive Eternal is built on the belief that the most enduring of these assets share common characteristics: they benefit from long-term stewardship, they compound through cultural resonance, and they are enhanced by technology rather than displaced by it. Our work at Thrive has always been informed and inspired by a deep appreciation for product, brand, and the ways in which consumers form lasting relationships with the things they love. We have been building towards this for a long time. Our first partnership is expected to be with the San Francisco Giants - an institution built on more than a century of shared identity and community, and among the most iconic sports franchises in America. We have reached an agreement, subject to league approval, to acquire an ownership stake. We feel privileged by the opportunity to be long-term partners to the Giants.
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Clark Square Capital
Clark Square Capital@ClarkSquareCap·
Excited to share that the Special Situations Digest has moved to a new home. If you want a free month of paid access (Pro), just do the following: retweet this, drop a comment below, and send me a DM with your email, and I will give you complimentary access.
Clark Square Capital tweet media
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Hego Damask retweetledi
Will Ahmed
Will Ahmed@willahmed·
You have no experience. You’ve never started a company. You’ve never had a full time job. Nike is going to kill you. You’re a kid. You don’t have technical skills. You shouldn’t build hardware. Apple is going to kill you. You can’t build hardware. You can’t measure heart rate non-invasively. Athletes don’t care about recovery. Under Armour is going to kill you. It won’t be accurate. You don’t listen. You’re an ineffective leader. You can’t recruit great talent. You’re going to have to pay every athlete. You can’t measure sleep non-invasively. It’s too expensive to research. Athletes are a small market. The product costs too much to make. The product costs too much to sell. Your valuation is too high. Consumers aren’t going to want it. Hardware is too hard. You should measure steps. Fitbit is going to kill you. You can’t build a marketing engine. You can’t raise enough money. You need a real CEO. Google is going to kill you. You can’t be a subscription. You can’t build a brand. You can’t do consumer in Boston. Your valuation is too high. You shouldn’t make accessories. You shouldn’t make apparel. Lululemon is going to kill you. You can’t predict Covid. Stay in your niche. You are going to run out of money. You can’t build a health platform. Amazon is going to kill you. You can’t measure blood pressure. You can’t get medical approvals. The market is too small. You don’t understand AI. The market is too competitive. It won’t work internationally. The supply chain is too complicated. You can’t build an AI. You can’t raise enough money. It’s too competitive. Healthcare isn’t going to want it. … Just keep going ✌️
Will Ahmed tweet media
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