Dan Rizzuto

Nia is now advancing quickly toward our first clinical trial in memory loss due to traumatic brain injury. There's much more to come in 2026.

🧠 Nia Therapeutics has received FDA Breakthrough Device Designation for our Smart Neurostimulation System — the first device to earn this designation for TBI-related memory loss. More than 4.3 million Americans live with TBI-related disability, and today there are zero FDA-approved treatments. The SNS listens to the brain across 60 channels and four brain regions, detects the precise moment when memory encoding is about to fail, and delivers AI-guided stimulation at that exact moment to rescue the memory network. In a randomized, sham-controlled study in patients with a history of traumatic brain injury, this closed-loop approach improved recall by 19%. In a follow-up study with improved stimulation targeting, the approach improved recall by 28%. This designation accelerates our path to first-in-human studies and gives us a closer working relationship with the FDA as we advance toward our Series A financing and an IDE application later this year. 📄 Full press release: businesswire.com/news/home/2026…

@gregorycampion @balajis Excellent question Greg.

Shouldn’t the current/recent conditions be the “prefect” set-up for bitcoin? Eg. exactly what we’ve been seeing in gold? Is it not worrying that despite such conditions, it hasn’t performed? What does this tell you? That the market believes it’s not actually a legit store of value?

Winners write history. So: if you do not write the history, you will not win. Fortunately, the Bitcoin blockchain is the most unfalsifiable form of history ever invented. A cryptohistory.

@micsolana Amen.

storming the church was not a small thing. it was an outrageous act of anti-social cruelty. it needs to be punished, and the people in media defending it need to be permanently marginalized. normalizing this is a path to hell.

@jonathanparnell Followed.

“I trust God so much that I do not doubt he will provide whatever I need for body and soul, and will turn to my good whatever adversity he sends upon me in this vale of tears. He is able to do this because he is almighty God; he desires to do this because he is a faithful Father.” (Heidelberg, Q26)

@WaLu1911 @RobbieSnipe @grok @pkpmarine @Eric_Weiner48 @sweatystartup @seandsweeney Buona sera!

@RobbieSnipe @grok @pkpmarine @Eric_Weiner48 @sweatystartup @seandsweeney WOP. With Out Papers. WOPs need not apply. That what my Italian grandparents were met with. They not only got no assistance they weren’t allowed most jobs. Also I remember my Grandmother forbidding speaking Italian. “We’re American now”

I have a family member who lives 20 minutes outside downtown Minneapolis in an apartment complex. Said half of the residents are Somalians here illegally. All of them on full welfare with rent paid. Everybody knows they all voted as well. She pays $1600 a month to live there. And she has a job. They do not (at least a taxable job) and live there for free. Why are people upset about what ICE is doing right now? There are 100,000 Somalians living in Twin Cities illegally. All getting welfare and rent. Why are hotels in NYC filled with immigrants and why is our government paying for it? Why are they allowed welfare without proof of citizenship? I'm far from a right winger. I generally don't care about politics or pay any attention. This just doesn't make any sense and anybody who argues for protecting this in any way is just an idiot. 99% of Americans would vote against illegal immigrants getting government assistance. Especially full rent payments. But they still do? Why? This is crazy. And people are still complaining about what is happening in MN right now? This is idiotic.

@alphafox It screams "I am difficult"

'Why do you hate septum rings'

@ArtemisConsort Keep going Hunter! Love your voice.

To commit oneself entirely to the truth, entirely to God, is the ideal. We will all necessarily fall short. The canceling out of our individual shortcomings via evolutionary pressure is how truth is found. The Godly person therefore invites competition and challenge. The rejection of challenge is the core of sin.

@fuckcomputer I can't see it. You may need Claude to adjust the settings.

claude code is fucking insane i know literally NOTHING about coding. ZERO. and i just built a fully functioning web app in minutes http://localhost:3000/ check it out

@lulumeservey Inspirational. Thanks!

GO DIRECT: THE MANIFESTO I. TRADITIONAL PR IS DEAD. For too long, founders have yielded control over their narratives to media and middlemen. Before the internet, it was by necessity. The way to reach large audiences was through the media, and the way to get media coverage was through professional publicists. Today, most of the planet is directly reachable by social media or email. There’s no longer a need to go through traditional gatekeepers of information and brokers of reputation — especially as their own credibility has plummeted. The old PR playbook of relying on third parties with misaligned interests is obsolete. But while the world has changed, comms norms have not. Still encased in amber are the old habits: prioritizing media over social media, fishing for clicks instead of fostering communities, and avoiding risk by recycling worn-out tactics. “Corporate communications” itself is now an oxymoron, as nothing meaningful can be communicated by a faceless committee. If press releases read like they were written by a baker’s dozen of middle managers, that’s because they were. Their only discernible purpose seems to be to avoid upsetting anyone and jeopardizing the future job prospects of those middle managers. The resulting stories are bland and generic, with passion reduced to pablum. Traditional comms is an anachronism. II. COMMUNICATION IS THE FOUNDER’S JOB. For a decade, we’ve been told that tech founders are cartoon villains, venture-funded startups are grifts, and new technologies will destroy us all. Maybe there was a time when founders could just focus on building — they were seen by the media establishment as a curiosity, not a threat to the natural hierarchy who needed to be put in their place. But if that time ever existed, it is now long gone. You may not be interested in The Discourse, but it is interested in you. And if you bow out, you are forfeiting your license to build a movement and thus build a company. Building a movement is hard, but it must be done, and it must be done by founders. A founder’s passion, vision, and conviction can’t be simulated by others — least of all the press-release-enjoying middle managers already scouting for their next jobs. The best spokesperson for any endeavor is not the one who has the most polish, the longest tenure, or the “right” credentials. It’s the person who holds the secret knowledge upon which the enterprise is built, the person who can not only describe the idea but, in the face of inevitable opposition, fight for it and win. Founders need to take their narrative as seriously as they take the rockets or robots. They would never outsource their product — and when it comes to convincing others to support the mission, the story is the product. Outsourcing comms is as bad as outsourcing code. As evangelists, founders are irreplaceable. III. GO DIRECT OR GO HOME. Going direct to the people who matter is how founders retain control over their narratives and preserve their companies’ uniqueness. Those who are stubborn, unorthodox, and disagreeable should never have their edges filed down for fear of offending entrenched interests. But going direct doesn’t mean going it alone. It doesn’t mean refusing help or spurning others who can amplify your message. And it certainly doesn’t mean just poasting more. Going direct means crafting and telling your own story, without being dependent on intermediaries. Just as founders might have more natural talents at product, management, or engineering, some founders will be naturals at communicating while others have a harder time. The good news is that going direct and building a movement, while not easy, are skills that can be developed with discipline and time. The bad news is that, unlike with engineering or management, communications failures are immediately public and personally humiliating. It’s not surprising that many are loathe to take on this responsibility. At the same time, founders willing to pick up that gauntlet will find that it gives them a massive edge in recruiting, fundraising, selling, and shaping the information environment needed for their companies to thrive. IV. IT’S TIME TO REBUILD THE ROSTRA. At the center of Rome, as it transitioned from a Republic to an Empire, stood a speaker’s platform from which the city’s leaders would address the public directly. It was called the Rostra, so named because it stood atop the captured battle rams (or rostrums) of enemy warships. From here, speeches were given that would sway opinion, change regimes, and alter history. That physical structure has been lost to time, but we now have something much more powerful: a free and open internet with which to build a speaker’s platform of limitless scale. All we need is the will to build it. The conventional way of communicating has its allure. Outsource your message, let some removed third party go through the motions of getting “impressions,” and spare yourself the risks and discomfort that come with putting your own name on the line. But that way is incompatible with greatness. Reject convention — build your own platform, build your own audience, and build your own narrative. Go direct.

@esrtweet Good and evil clearly exist in this universe, Eric. It's ignorance to claim otherwise, not cowardice to recognize it.

This is cowardice. And it's disappointing.

@JanCBS @CBSEveningNews @tonydokoupil This is an excellent turn of events! I'm looking forward to tuning in to CBS more often nowadays.

To the thousands of you who took time to respond and share your thoughts about our new @CBSEveningNews with @tonydokoupil, thank you. I tried to read most of your comments, and I appreciate the many constructive points and encouraging/hopeful replies. I also understand your skepticism and anger. I agree. We have to be better, and we are going to do our best to prove we can be. Please tune in again tomorrow night, and let me know what you think in the days and months ahead as we strive to get it right.

@rjackcarlson @vw_chen @AlexAlmeida2020 Bingo.

@vw_chen @AlexAlmeida2020 Iraq and Afghanistan failed to become Nations after we left because the Iraqis and Afghanis are the primary occupants of those lands.

This will do more for US soft power in Latin America than any billions of US aid and NGO money. Not because Maduro is unpopular, though he is, but because at the level of basic animal psychology, nothing succeeds like success 1/2

@sam_gzstrength And What body fat percentage would you target at that weight?

Highest BW I've been was about 247-250 before cutting to 242 for a meet where I was trying to pull 600 I regret not taking myself to 265-275 TBH 305 would be my competitive strength weight for sure though

BODYWEIGHT FOR MAXIMIZING MY STRENGTH POTENTIAL Directly from the man himself during this week's paper Q&A I'm currently 6'4 and 205 in hybrid athletard mode At 6'4 Rip says I need to be 305 pounds to maximize my strength potential He would be correct.

@ArthurMacwaters Where did the $1.5T number come from?

this is shocking: > US collects $2.4T in income tax, but spends $1.5T on fraud > if we didn't have to pay for fraud, only $900b would need to be collected > this means anyone with less 500k in income could pay *literally $0* in income tax we don't need to raise taxes. we need to cut fraud

@JewishSpaceLazr @EndWokeness @grok @grok how large is the Somali electorate in MN?

@EndWokeness @grok can this be real?? Has the entire state of Minnesota suffered some sort of psychotic break??

BREAKING: MN Lt. Governor Flanagan puts on hijab, declares Somalis built Minnesota

@jared_shult Being pro life does not mean you need to support a literal nanny state. People have been supporting their own children for hundreds of thousands of years without help from the state. Fostering dependency is a disease.

MAGA is always pro life until children have to be taken care of

@boriquagato @kareem_carr Government investment in R&D is largely responsible for US dominance in advanced technology development. Remove the investment, and watch other countries take the lead. China is already taking the lead in cellular networks, drones, robotics, and EV

disagree. government funding of science has always been a terrible idea. it turns science political and allocates money around patronage and partisan position. this has broken science badly it's exactly what ike warned against in his farewell address. and he looks more prescient by the day.

it’s probably not great that more and more americans see funding science as a special favor they’re doing for universities, instead of as critical infrastructure a superpower needs, like roads or aircraft carriers.

@sethmoulton No, communism is evil.

Housing is a human right. Health care is a human right. Education is a human right.

Eric, I often agree with you, but not this time. Science and technology is how we advance as a civilization. Investing in R&D is one of the key ways that the US maintains its competitive advantage. Canceling science and tech funding is shooting ourselves in the foot. We should reform the system where necessary, not throw the baby out with the bathwater.

@kareem_carr Live by political ratfucking, die by political ratfucking. The "research community" earned this.