Dan Rizzuto

Nia is now advancing quickly toward our first clinical trial in memory loss due to traumatic brain injury. There's much more to come in 2026.

@NASA @NASAMoonBase America is so back!

We're building a Moon Base! @NASAMoonBase will serve as a habitat where astronauts live and work during long-term science missions. Join us at 2pm ET on Tuesday, May 26, for a live news event where we’ll share updates on our lunar exploration plans: go.nasa.gov/4uinkLi

@CircumjovialLLC @OpenAI It is a human achievement. Who created the model? Humans.

@OpenAI This is not a human achievement. We exist for human achievement. A world where we are all passive observers while AI models do all the achieving is a nightmarish dystopia and humanity can choose not to take that path.

Today, we share a breakthrough on the planar unit distance problem, a famous open question first posed by Paul Erdős in 1946. For nearly 80 years, mathematicians believed the best possible solutions looked roughly like square grids. An OpenAI model has now disproved that belief, discovering an entirely new family of constructions that performs better. This marks the first time AI has autonomously solved a prominent open problem central to a field of mathematics.

@NiaTherapeutics is hiring a Manufacturing Engineer to lead process development for our implantable depth lead — the component at the heart of our Smart Neurostimulation System. The SNS is an AI-guided neurostimulator designated a Breakthrough Device by the FDA earlier this year for the treatment of memory loss following traumatic brain injury. This is hands-on work: process qualification, root-cause investigation, time at the bench at Nia and at our contract manufacturing partners. If you've worked on Class III active implantables — neural leads, DBS leads, IPGs, cardiac leads — and want to build something that restores memory to people who've lost it, come talk to us. On-site in Allston, MA. Open to Senior, Staff, or Principal levels. Link to the job description and application in the thread.

Come build the future of brain computer interface technology at @NiaTherapeutics

@cyrilXBT @Readwiseio save

@trq212 @readwise save thread

@AOC The idea that all billionaires got their money by exploiting peopl doesn't hold up to any scrutiny. JK Rowling wrote books about cheeky wizards. I invented a better way to make virtual reality headsets and games to play on them. We just made things people wanted.

@businessbarista AI-native

I want to start an AI community for executives. This will be a space for people to share killer use cases, agentic workflows/agents, post-AI org structure, AI governance, AI training/enablement, change management, and more. Comment “AI-native” if you want to join.

@ArtemisConsort Amen, brother.

@SergeyStavisky @NiaTherapeutics Thanks, @SergeyStavisky !

@NiaTherapeutics @DanRizzuto Congratulations!

🧠 Nia Therapeutics has received FDA Breakthrough Device Designation for our Smart Neurostimulation System — the first device to earn this designation for TBI-related memory loss. More than 4.3 million Americans live with TBI-related disability, and today there are zero FDA-approved treatments. The SNS listens to the brain across 60 channels and four brain regions, detects the precise moment when memory encoding is about to fail, and delivers AI-guided stimulation at that exact moment to rescue the memory network. In a randomized, sham-controlled study in patients with a history of traumatic brain injury, this closed-loop approach improved recall by 19%. In a follow-up study with improved stimulation targeting, the approach improved recall by 28%. This designation accelerates our path to first-in-human studies and gives us a closer working relationship with the FDA as we advance toward our Series A financing and an IDE application later this year. 📄 Full press release: businesswire.com/news/home/2026…

@gregorycampion @balajis Excellent question Greg.

Shouldn’t the current/recent conditions be the “prefect” set-up for bitcoin? Eg. exactly what we’ve been seeing in gold? Is it not worrying that despite such conditions, it hasn’t performed? What does this tell you? That the market believes it’s not actually a legit store of value?

Winners write history. So: if you do not write the history, you will not win. Fortunately, the Bitcoin blockchain is the most unfalsifiable form of history ever invented. A cryptohistory.

@micsolana Amen.

storming the church was not a small thing. it was an outrageous act of anti-social cruelty. it needs to be punished, and the people in media defending it need to be permanently marginalized. normalizing this is a path to hell.

@jonathanparnell Followed.

“I trust God so much that I do not doubt he will provide whatever I need for body and soul, and will turn to my good whatever adversity he sends upon me in this vale of tears. He is able to do this because he is almighty God; he desires to do this because he is a faithful Father.” (Heidelberg, Q26)

@WaLu1911 @RobbieSnipe @grok @pkpmarine @Eric_Weiner48 @sweatystartup @seandsweeney Buona sera!

@RobbieSnipe @grok @pkpmarine @Eric_Weiner48 @sweatystartup @seandsweeney WOP. With Out Papers. WOPs need not apply. That what my Italian grandparents were met with. They not only got no assistance they weren’t allowed most jobs. Also I remember my Grandmother forbidding speaking Italian. “We’re American now”

I have a family member who lives 20 minutes outside downtown Minneapolis in an apartment complex. Said half of the residents are Somalians here illegally. All of them on full welfare with rent paid. Everybody knows they all voted as well. She pays $1600 a month to live there. And she has a job. They do not (at least a taxable job) and live there for free. Why are people upset about what ICE is doing right now? There are 100,000 Somalians living in Twin Cities illegally. All getting welfare and rent. Why are hotels in NYC filled with immigrants and why is our government paying for it? Why are they allowed welfare without proof of citizenship? I'm far from a right winger. I generally don't care about politics or pay any attention. This just doesn't make any sense and anybody who argues for protecting this in any way is just an idiot. 99% of Americans would vote against illegal immigrants getting government assistance. Especially full rent payments. But they still do? Why? This is crazy. And people are still complaining about what is happening in MN right now? This is idiotic.

@alphafox It screams "I am difficult"

'Why do you hate septum rings'

@ArtemisConsort Keep going Hunter! Love your voice.

To commit oneself entirely to the truth, entirely to God, is the ideal. We will all necessarily fall short. The canceling out of our individual shortcomings via evolutionary pressure is how truth is found. The Godly person therefore invites competition and challenge. The rejection of challenge is the core of sin.

@fuckcomputer I can't see it. You may need Claude to adjust the settings.

claude code is fucking insane i know literally NOTHING about coding. ZERO. and i just built a fully functioning web app in minutes http://localhost:3000/ check it out

@lulumeservey Inspirational. Thanks!

GO DIRECT: THE MANIFESTO I. TRADITIONAL PR IS DEAD. For too long, founders have yielded control over their narratives to media and middlemen. Before the internet, it was by necessity. The way to reach large audiences was through the media, and the way to get media coverage was through professional publicists. Today, most of the planet is directly reachable by social media or email. There’s no longer a need to go through traditional gatekeepers of information and brokers of reputation — especially as their own credibility has plummeted. The old PR playbook of relying on third parties with misaligned interests is obsolete. But while the world has changed, comms norms have not. Still encased in amber are the old habits: prioritizing media over social media, fishing for clicks instead of fostering communities, and avoiding risk by recycling worn-out tactics. “Corporate communications” itself is now an oxymoron, as nothing meaningful can be communicated by a faceless committee. If press releases read like they were written by a baker’s dozen of middle managers, that’s because they were. Their only discernible purpose seems to be to avoid upsetting anyone and jeopardizing the future job prospects of those middle managers. The resulting stories are bland and generic, with passion reduced to pablum. Traditional comms is an anachronism. II. COMMUNICATION IS THE FOUNDER’S JOB. For a decade, we’ve been told that tech founders are cartoon villains, venture-funded startups are grifts, and new technologies will destroy us all. Maybe there was a time when founders could just focus on building — they were seen by the media establishment as a curiosity, not a threat to the natural hierarchy who needed to be put in their place. But if that time ever existed, it is now long gone. You may not be interested in The Discourse, but it is interested in you. And if you bow out, you are forfeiting your license to build a movement and thus build a company. Building a movement is hard, but it must be done, and it must be done by founders. A founder’s passion, vision, and conviction can’t be simulated by others — least of all the press-release-enjoying middle managers already scouting for their next jobs. The best spokesperson for any endeavor is not the one who has the most polish, the longest tenure, or the “right” credentials. It’s the person who holds the secret knowledge upon which the enterprise is built, the person who can not only describe the idea but, in the face of inevitable opposition, fight for it and win. Founders need to take their narrative as seriously as they take the rockets or robots. They would never outsource their product — and when it comes to convincing others to support the mission, the story is the product. Outsourcing comms is as bad as outsourcing code. As evangelists, founders are irreplaceable. III. GO DIRECT OR GO HOME. Going direct to the people who matter is how founders retain control over their narratives and preserve their companies’ uniqueness. Those who are stubborn, unorthodox, and disagreeable should never have their edges filed down for fear of offending entrenched interests. But going direct doesn’t mean going it alone. It doesn’t mean refusing help or spurning others who can amplify your message. And it certainly doesn’t mean just poasting more. Going direct means crafting and telling your own story, without being dependent on intermediaries. Just as founders might have more natural talents at product, management, or engineering, some founders will be naturals at communicating while others have a harder time. The good news is that going direct and building a movement, while not easy, are skills that can be developed with discipline and time. The bad news is that, unlike with engineering or management, communications failures are immediately public and personally humiliating. It’s not surprising that many are loathe to take on this responsibility. At the same time, founders willing to pick up that gauntlet will find that it gives them a massive edge in recruiting, fundraising, selling, and shaping the information environment needed for their companies to thrive. IV. IT’S TIME TO REBUILD THE ROSTRA. At the center of Rome, as it transitioned from a Republic to an Empire, stood a speaker’s platform from which the city’s leaders would address the public directly. It was called the Rostra, so named because it stood atop the captured battle rams (or rostrums) of enemy warships. From here, speeches were given that would sway opinion, change regimes, and alter history. That physical structure has been lost to time, but we now have something much more powerful: a free and open internet with which to build a speaker’s platform of limitless scale. All we need is the will to build it. The conventional way of communicating has its allure. Outsource your message, let some removed third party go through the motions of getting “impressions,” and spare yourself the risks and discomfort that come with putting your own name on the line. But that way is incompatible with greatness. Reject convention — build your own platform, build your own audience, and build your own narrative. Go direct.

@esrtweet Good and evil clearly exist in this universe, Eric. It's ignorance to claim otherwise, not cowardice to recognize it.

This is cowardice. And it's disappointing.