

A. Joseph Borelli, Jr., MD
28.5K posts

@DocBorelli
🩻 Radiologist & MRI clinic owner | Chaired committee writing U.S. MRI accreditation standards | Filmmaker | All tweets IMO | No investment/medical advice







NEW: Ferrari unveils the Luce, its first electric vehicle designed by Jony Ive.


Eli Lilly has done it. They've gone and made what seems to be a powerful, permanent gene therapy for LDL cholesterol. That means they'll be able to effectively prevent most heart disease with a single infusion!



🚨 INSANE: A transgender activist admitted to @sircalebhammer that Colorado taxpayers covered the cost of transition procedures, hormone treatments, and breast augmentation through state-funded health coverage. 😳 Colorado expanded protections for gender-affirming care under HB25-1309 signed by Gov. Jared Polis. Taxpayer money should not be funding transition surgeries. Period.








I'm lucky enough to have a great doctor and access to excellent Bay Area medical care. I've taken lots of standard screening tests over the years and have tried lots of "health tech" devices and tools. With all this said, by far the most useful preventative medical advice that I've ever received has come from unleashing coding agents on my genome, having them investigate my specific mutations, and having them recommend specific follow-on tests and treatments. Population averages are population averages, but we ourselves are not averages. For example, it turns out that I probably have a 30x(!) higher-than-average predisposition to melanoma. Fortunately, there are both specific supplements that help counteract the particular mutations I have, and of course I can significantly dial up my screening frequency. So, this is very useful to know. I don't know exactly how much the analysis cost, but probably less than $100. Sequencing my genome cost a few hundred dollars. (One often sees papers and articles claiming that models aren't very good at medical reasoning. These analyses are usually based on employing several-year-old models, which is a kind of ludicrous malpractice. It is true that you still have to carefully monitor the agents' reasoning, and they do on occasion jump to conclusions or skip steps, requiring some nudging and re-steering. But, overall, they are almost literally infinitely better for this kind of work than what one can otherwise obtain today.) There are still lots of questions about how this will diffuse and get adopted, but it seems very clear that medical practice is about to improve enormously. Exciting times!









Here are the facts about @elonmusk: He USED to be great! He made the impossible possible. But in the past 4 years in particular, he himself has become a "pompous retard," as demonstrated by this tweet where he calls some kid a "pompous retard" because the proud kid has "PhD at 19" in his bio. The kid is now 22! It's no wonder Elon is behind on everything! He's become such an ass, that NO TALENT WANTS TO WORK FOR HIM! Let's look at Elon's record over the past 4 years: Let's start with $TSLA: - Talent has flooded out of Tesla. Big names, like Andrej Karpathy (@karpathy), previously heading Tesla AI team, left years ago (now at Anthropic). Head of RoboTaxi left not long ago also. Heads of other teams/vehicles/research have also left. The talent drain has been across the board and Tesla is feeling it! - RoboTaxi, launched 1 year ago in June, was expected to have over 1 Million vehicles by now. So far, around 20 vehicles! And don't ask about the accident rates! - Optimus, originally planned for launch last year with "thousands of units" with "millions by 2026/27" and eventually "billions" has not delivered even 1 yet. Plus ALL the demos of Optimus have been remote operated with some embarrassing fails! Other robotics companies, like Figure, are driving circles around Optimus with their demos! - Tesla Solar: practically dead. Solar Roof: no longer even talked about! - Tesla Semi, Roadster 2, Model 2 (or $25K vehicle), all massively late or canceled! - Nearly EVERY Tesla project has fallen way behind. - Revenues: DOWN year-over-year for 2 years now! No obvious path to meaningful revenue growth in at least 2026. Profits: down massively...might go into red soon. On to SpaceX $SPCX: - First Booster+Starship demo launch happened in April of 2023. At the time, Elon set the expectation that there would be a new test launch about every 6 weeks or so, with expected "prep mission to Mars to take payload to prepare for manned missions to Mars by 2024 or 2026 at the latest." (paraphrased) 3 years later, we just got another Booster+Starship demo that was about on-par with the original. Sure a lot has changed/improved over the past 3 years, but this is a MAJOR letdown from expectations set by Elon. - Remember the "Dear Moon" launch of Starship with a 9-person crew filled with prominent artists, digital creators, and celebrities? That was supposed to launch in 2023! Quietly canceled. No update! - SpaceX Revenues: up just 33% year-over-year in 2025 and latest quarter (Q1 2026) was up just 15% year-over-year On X and xAI: - After two years of touting xAI's Grok as the absolute best AI, far superior to the woke OpenAI ChatGPT and "Miss"Anthropic's Claude, Elon finally admitted that xAI sucked and they needed to start from scratch a few months ago. He even admitted they mis-hired! - Twitter revenue was ~$5 Billion annually when Elon took over. Now, X (formerly Twitter) + xAI combined revenue is ~$3 Billion annually. Don't even get me started on the expectations he set with Boring Company and Neuralink, and what has been delivered so far! ---------------------------------- The facts are that in the last 4 years, Elon has become the pompous retard, not this poor kid, @iScienceLuvr. As a result, not many people want to work their asses off so that only Elon can get credit for all of their work with a Trillion-Dollar pay package while they work for 1/1,000,000th of that! (if they're lucky!)

