Evita Sadimin

Great to catch up with ⁦@ESadimin⁩ during #KCRS2024. “It’s all about negative margins.” ⁦@CityofHope_GU⁩ ⁦@OSUCCC_James⁩ ⁦@OSU_Urology⁩

Interesting #gupath case: poorly differentiated carcinoma w/squamous features involving the bladder - note the squamous component in the deep portion of low mag pic, more prominent in the high mag H&E and GATA-3 stain in the residual predominantly denuded urothelial surface 1/3

For our 2023 #pathology trainees, remember this #GUPath adage👇 “Not all renal tumors with clear cells are clear cell renal cell carcinoma” … spot on in this molecular era! 👇Below are DDX for Clear cell #RCC including #renal tumors with some degree of cytoplasmic clearing🔬

May is #bladdercancerawarenessmonth - important to recognize lesions which mimic #bladdercancer Nephrogenic metaplasia/adenoma: - various architectures (papillary, tubular/glandular, vascular-like...) - cuboidal to hobnail nuclear features - prominence of basement membrane

May 2023 is #bladdercancerawarenessmonth Urothelial carcinoma can invade the prostate, mimic high grade #prostatecancer & occasionally be sampled on needle biopsy (see PICS) #gupath

#GUPath times two ✌️ Exquisitely rare nephroblastoma (Wilms’ tumor) arising from a testicular germ cell tumor.

Perineural Involvement by benign prostatic glands 🚨may mimic #prostatecancer kikoxp.com/posts/20099 #gupath

@rovingatuscap @Williamson_SR @slusagar @LaraHarikMD @priyaraomd @lalpritu @Gleason4plus5 @johncheville @daniel_berney @evacomperat @h_alahmadie 4+5=9 (GG5)

Always a challenge: #prostatecancer with extensive vacuolization #gupath How would you grade this: 4+3=7, 4+4=8, 3+5=8, 4+5=9, 5+4=9?

Benign Prostatic Tissue with Radiation Therapy Effect #gupath #prostate Learn more here▶️kikoxp.com/posts/19869

Rare encounter of lymphovascular invasion of #prostate cancer in biopsy. #GUPath

Nice example of the rare Inverted #urothelial papilloma arising from prostatic #urethra, incidentally encountered on radical prostatectomy. PMID: 16861968 by @rovingatuscap #GUPath

Morphologic Manifestations of BENIGN #prostate tissue with profound treatment (radiation☢️) effect: - Dense eosinophilic cytoplasm - Peri-glandular fibrosis - Multi-layered cells with reactive nuclear & nucleolar atypia

Morphologic manifestations of Regression in Clear Cell Renal Cell Carcinoma - Cell drop out - Edema - Fibrosis/sclerosis - Vascular prominence #kidneycancer #KidneyWk #gupath

@LisaRooperMD These are amazing! I can never create anything good with text to image platforms :(

This micropapillary urothelial carcinoma spread to the duodenum. Nasty nasty tumor.

@zafirahzahir It was a typical prostate biopsy done for elevated PSA

@ESadimin what was the clinical presentation of the patient

Prostate biopsy with perivascular amyloid deposition. Don't forget to look beyond the glands! #pathology #pathologists #GUpath #pathboards

@slusagar @JaneNguyen44 @TheUSCAP Yes mainly perivascular. Typing was ATTR. Had a case a while ago that was AL in patient without prior amyloid or plasma cell related dx!

@ESadimin was this mainly perivascular? @JaneNguyen44 can you chime in too? (related to your excellent @TheUSCAP platform on this topic this year) also, ✔️recent study

We are pleased to announce Dr. Isaac Y. Kim as our new Chair of Urology. Welcome, Dr. Kim! bit.ly/3huC5s5 @YNHH @YaleMed @SmilowCancer @YaleCancer

Something I learned from @JMGardnerMD. Gout crystals can be visualized under polarization on unstained FFPE slide, without red compensator filter. Coverslip is not necessary, but it looks better with one. #pathology #pathologists #pathboards @PathologyRWJMS