Ed Linossi 🔬

You are what you eat! We leveraged chemical proteomics to discover that macrophages redeploy intact surface proteins made by their cancer cell meals during phagocytosis. These proteins are functional, and redeployment may explain the etiology of the TAM. biorxiv.org/content/10.110…

😀Excited to share our new findings in @CellCellPress! cell.com/cell/fulltext/… Dynamic allostery drives autocrine and paracrine TGF-ß signaling #TGFbeta #DynamicAllostery #CryoEM #StructuralBiology #MedicalInnovation

Please RT! Postdoctoral position for 2 years ⁦@scienceANU⁩ - if you are interested in infectious diseases #StructuralBiology #Nanobodies please apply - new program on chytrid fungus 💎 🦙 🐸 Postdoctoral Fellow (Tham) - Canberra / ACT, Australia jobs.anu.edu.au/jobs/postdocto…

Interested in Honours, Masters, or PhD studies in medical research? We have over 70 student research projects starting in 2025, across the breadth of research areas at WEHI. Explore the opportunities here: wehi.edu.au/education/stud… #WEHIStudents #StudyInMelbourne #UniMelb

I’m so very pleased to announce the opening of the LIMS Marilyn Anderson Fellowship application @LIMSLTU !!! in recognition of @ProfMarilynAnderson and in support of #WomenInScience Looking for high-achieving female scientist (level D) with a passion for molecular science

I'm very excited to share that I've been awarded a #DECRA fellowship to study how the gut microbiome impacts immune cells @MonashBiol. Its such an honour to receive this fellowship. Thanks to everyone who has helped me along this journey. #womeninSTEM

we are looking for a new Research Fellow at Ian Holmes Imaging Centre @Bio21Institute @UniMelb . If you are keen to expore new horizons and join a large electron microscopy facility this is for you. This is a continuing position. jobs.unimelb.edu.au/en/job/918151/…

In collaboration with @DavisLab_Oxford, published a study in @nature detailing cryo-EM structure of the gdTCR-CD3 integral membrane complex. Shows remarkable flexibility in this system rdcu.be/dQ2Ik @MonashBDI @MonashUni @benjaminsgully @arc_gov_au

As a scientist and science communicator, I'm appalled that Cosmos published AI generated articles and that it was funded by the Walkley Foundation. High quality science journalism is needed more than ever but it's being undermined by cost-cutting AI abc.net.au/news/science/2…

Mutations in the kinase domain of RTKs like MET can drive disease. Small molecule inhibitors target these mutations, but acquired resistance poses a challenge. In our latest preprint, we've extended our previous 🧬DMS of MET to study this exact problem. doi.org/10.1101/2024.0…

Join our team at @biomed_UCPH ❄️🔬We're hiring a 2-year postdoc in membrane protein structural biology and native nanodiscs 🌟 Exciting research, cutting-edge facilities, and a vibrant research community await you in beautiful Copenhagen 🇩🇰 Apply now! employment.ku.dk/faculty/?show=…

Come work at WEHI Proteomics and collaborate with us!

Come and join us @WEHI_research 👇

New paper alert! 13 protocols to spatially profile necroptosis in mice & human tissues – including in patients with IBD New methods = many surprises including RIPK3 going ⬆️ or⬇️ or↔️ in different disease settings Mega effort from many @wehi + @TheRMH embopress.org/doi/full/10.10…

Easily some of our most important work. Hats off to @AndreSamson15 and team, including terrific first authors @shene67732453 and @aysha_h_alani Thanks to the wonderful support @WEHI_research and from @nhmrc and @KR_Foundation

Interested in learning how dyes might help in characterizing protein activity? We're excited to share the development of a protein-adaptive DSF platform (paDSF), a dye-based method used to interrogate stability, dynamics, and ligand binding! go.nature.com/4ajNRNp

Thrilled to share a pre-print describing an elegant solution to overcome target size limitation of single particle #cryoEM, where we demonstrate high resolution (2.3 – 2.5 Å) structure determination of small (~20 kDa) ordered proteins using cryoEM! biorxiv.org/content/10.110…

Please RT and encourage students and early career researcher folks to apply for this fantastic ECR venom symposium! Join us for the 2024 venom GRS in beautiful Portland Maine from 10-11 August! #GRCvenom24 is 11-16 Aug! Register here: tinyurl.com/yd8fw8fa

Awesome to see this fantastic study of the elusive EphB6 pseudokinase in print at long last nature.com/articles/s4200… Massive congrats to star PhD student @LungYu_Liang (now in Frankfurt) who bravely took on this toughest of projects with @Isa_Lucet and me