Sara-Jane Dunn

488 posts

Sara-Jane Dunn

Sara-Jane Dunn

@EssJayD

Research scientist at Relation Therapeutics. Interested in what cells compute. (A little twitter shy, but any comments my own.)

Cambridge, UK Katılım Mayıs 2013
417 Takip Edilen1K Takipçiler
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Jue Wang
Jue Wang@jueseph·
My team at Deepmind (protein design) is hiring an experimentalist with enzyme expertise. Please RT and/or apply! I'm happy to answer any questions as well. boards.greenhouse.io/deepmind/jobs/…
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Austin Smith
Austin Smith@AustinS10301165·
New scRNA-seq analysis platform from Arthur Radley Branching topology of the human embryo transcriptome revealed by entropy sort feature weighting biorxiv.org/content/10.110…
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Owen Rackham
Owen Rackham@OwenRackham·
We seek a Research Fellow in Computational Biology to join our team at the @unisouthampton . I would be happy to chat with anyone interested in the position about the role, project, or environment we create for you to work in. jobs.soton.ac.uk/2462523BJ
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James Briscoe
James Briscoe@briscoejames·
Surprised, delighted, and overawed to be elected an International member of the American Academy of Arts & Sciences @americanacad A huge honour, made even more so by the inspiring accomplishments of the other new members
American Academy of Arts & Sciences@americanacad

Congratulations to our new members! Just announced! We are honoring the excellence of extraordinary leaders in an array of disciplines and professions. The first members were elected in 1781. Learn who was elected in 2023: amacad.org/news/2023-memb…

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Sara-Jane Dunn
Sara-Jane Dunn@EssJayD·
Proud to see the work of an excellent PhD student, Arthur Radley, now published in @stemcellreports - a cool method to do feature selection in single cell data mitigating noise cell.com/stem-cell-repo… Work together with Austin Smith, Elena Corujo-Simon and Jenny Nichols
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Demis Hassabis
Demis Hassabis@demishassabis·
Thrilled to announce the launch of a new Alphabet company @IsomorphicLabs. Our mission is to reimagine the drug discovery process from first principles with an AI-first approach, to accelerate biomedical breakthroughs and find cures for diseases. Details: isomorphiclabs.com/blog
Demis Hassabis tweet media
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Pushmeet Kohli
Pushmeet Kohli@pushmeet·
Happy to see Nature Methods publish our team’s work on using AI to improve prediction of how DNA sequence influences gene expression. Our first step in research on improving understanding of the fundamental building blocks of life.
Google DeepMind@GoogleDeepMind

Published today in @naturemethods together with colleagues from @calico: Enformer - a transformer model that has led to greatly increased accuracy in predicting gene expression from DNA sequence. Blog: dpmd.ai/enformer Paper: dpmd.ai/naturemethods_… 1/

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Pushmeet Kohli
Pushmeet Kohli@pushmeet·
Big day for team #AlphaFold! The human proteome & the 20 organisms we are sharing today have been the subject of countless research papers & breakthroughs over time. By sharing this foundational resource, we hope to aid many more scientists in their work; present & future!
Google DeepMind@GoogleDeepMind

Today with @emblebi, we're launching the #AlphaFold Protein Structure Database, which offers the most complete and accurate picture of the human proteome, doubling humanity’s accumulated knowledge of high-accuracy human protein structures - for free: dpmd.ai/alphafolddb 1/

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Google DeepMind
Google DeepMind@GoogleDeepMind·
Today with @emblebi, we're launching the #AlphaFold Protein Structure Database, which offers the most complete and accurate picture of the human proteome, doubling humanity’s accumulated knowledge of high-accuracy human protein structures - for free: dpmd.ai/alphafolddb 1/
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Sara-Jane Dunn
Sara-Jane Dunn@EssJayD·
@mincle Ah yes, didn't mention this so thanks for asking. You don't need complete data - you can have partial constraints (e.g. only a few of the genes measured) and the solver will apply what is told must hold.
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Sara-Jane Dunn
Sara-Jane Dunn@EssJayD·
@mincle We used correlation to identify possible interactions, but that's not the only approach. General (not v. exciting) rule of thumb: the more possible interactions, the more constraints you'll need to reduce the uncertainty to the point where you have a predictive set of models.
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Sara-Jane Dunn
Sara-Jane Dunn@EssJayD·
@mincle It's a tricky qus to answer as really it depends on the number of possible vs definite interactions, and then how much 'diverse' behaviour the constraints capture (e.g. perturbations that elicit different dynamics).
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