Federico Marchini

Just published on @ESCHeartFailure our meta-analysis on the prognostic role of T1 mapping in NIDCM. Both T1 mapping and ECV were associated with increased risk of the primary endpoint of MACE and the secondary endpoint of heart failure and arrhythmic-related events.

🚨 - Male, 72 yo - 2020 unremarkable coronary angiography - since then several episodes of chest tightness - admitted for worsening symptoms to ICU at #OspedaleFornaroli @negrofrancesco0 @ariannalissoni @jinweisun

Tricuspid satisfaction 🫀 #echofirst @ritapavasini87 @ElisabettaBex @GiuliaPassarini @NMerke (I know, not a perfect ALAMO )

#EHJCVI 📏 Should we use sex-specific thresholds for LV hypertrophy in Fabry disease? LVMWT >10 mm in women and >13 mm in men are independently associated with mortality, hospitalization, AF, major arrhythmias, and stroke ⚖️📊 👉 doi.org/10.1093/ehjci/…

Among patients with atrial fibrillation at high risk for stroke and bleeding, left atrial appendage closure was not noninferior to medical therapy in reducing the risk of stroke, embolism, major bleeding, or death at 3 years. Full CLOSURE-AF trial results: nejm.org/doi/full/10.10… Editorial: Left Atrial Appendage Closure — Another Overused Method in Cardiology? nejm.org/doi/full/10.10…

NEW CONSENSUS OUT 🫀Atrial Cardiomyopathy is distinct entity marked by structural, functional & electrical abnormalities → AF, HF & adverse CV events. Clinical assessment alone isn’t enough. 🎥 Multimodality imaging is key
✅ Early detection
✅ Risk stratification @escardio

🫀 Zero CAC doesn’t mean zero risk. Fitness matters. A new analysis from the SCAPIS cohort (n=2,322) shows something clinically important: even in middle-aged individuals with a coronary artery calcium (CAC) score of 0, low cardiorespiratory fitness (CRF) is strongly associated with underlying coronary atherosclerosis. 🔎 Key findings: • 6.6% of individuals with CAC = 0 had CCTA-detected atherosclerosis • Each +1 ml/kg/min increase in CRF was associated with ~4–5% lower odds of plaque • Low CRF was linked to more than double the prevalence of atherosclerosis – Men: 9.8% vs 4.8% – Women: 10.9% vs 4.8% • Adding CRF to SCORE significantly improved risk discrimination 🚨 The critical message: CAC detects calcified plaque. It does not exclude non-calcified, potentially vulnerable plaque. This study reinforces that: ✔️ CRF is independently associated with subclinical coronary disease ✔️ CRF adds value beyond traditional risk scores ✔️ “Low-risk” patients with CAC=0 may still harbor meaningful plaque burden Women with low CRF and SCORE ≥1% showed particularly high prevalence (≈15%). 📌 Clinical implication: CRF should not be treated as a lifestyle afterthought — it behaves like a cardiovascular vital sign. In an era where CAC is increasingly used to “rule out” disease, this study reminds us: physiology still matters. Fitness is not just about longevity. It may help identify hidden atherosclerosis before events happen. Exercise capacity is risk biology.

Our #EHJ review highlighting the expanding role of 3D echo in valvular heart disease — from native & prosthetic valve assessment to surgical planning & transcatheter guidance. An honor working with my co-authors on this collaboration. ➡️doi.org/10.1093/eurhea… #CardioX #Cardiotwitter #Echofirst #3Decho #iecho

@MarcoSa52466127 @bwoody58 @DrRajeshG1 @iamritu @CASivaram1 @DavidWienerMD @OungSavly @echo_stepbystep @StellEkaterina @NMerke @echo_batman @FGraziani_Grace @VDelgadoGarcia @VerwerftJan @alexsfelixecho @KemalogluOz @LHoyesWouter I do the same Marco #FlexiSlice - and I usually put labels (also for better #echofirst spatial orientation)

💎Liberación de la Ventilación Mecánica en la UCI Cardiovascular🫀🫁 🔰📚JACC 2023 doi.org/10.1016/j.jaca… Enlace a Artículo Completo👇🏼🆓✅ t.me/SoMELaguna

This narrative review describes current guidelines for intervention in severe primary #MitralRegurgitation and explores an approach that incorporates additional injury assessment, novel imaging markers, and biomarkers to optimize surgical timing. ja.ma/4kgFx7T

@ElisabettaBex @mari_lomonaco93 @FedericaFras @AlbertoCossu5 @laurarotondo25 @Matser89 @GianlucaCampo78 @siufille

Pathognomonic CMR case of cardiac amyloidosis. ✅ Severe hypertrophy (IVS 22 mm) ✅ Severe increase of T1 mapping (1150 Ms) and ECV (65%) ✅ Diffuse subendocardial LGE with apical sparing and involvement of RV and atrial. #yescmr #echofirst #cardiacimaging

@ritapavasini87 @GianlucaCampo78 @AlbertoCossu5 @laurarotondo25 @FedericaFras

Just published in the "Echocardiography" journal our latest paper on the role of speckle tracking echocardiography in transfusion dependent beta-thalassemia 🫀 ✅ STE had high diagnostic accuracy to detect AF patients Fantastic work, thanks all! doi.org/10.1111/echo.7…

🔴10 Issues for the Clinician in TR Evaluation & Management: 2025 ACC Expert Consensus Decision Pathway: A Report @JACCJournals #Cardiology #CardioEd #FOAMed #echofirst #WhyCMR

How to do mitral valve with 3D #echofirst Always starting with good 2D and think #ALAMO 👉Annulus within 2D Datablock 👉Leaflet within 2D Datablock 👉(no) Artifacts within 2D Datablock 👉Movement of leaflets with data block 👉Orientation (Landmarks) #3DEchoBerlin

Findings?

@iamritu @DipanJShah @alexsfelixecho @alex1708ander @ASE360 @echo_stepbystep @rajdoc2005 @SCMRorg My #echofirst take on this #3DEchoBerlin

📌 case of the day: massive TR of a complex etiology: functional (right atrial and ventricular dilation, RV and LV dysfunction) ➕ degenerative leaflets with fibrotic thickening. Challenging to determine the primary cause vs the consequence and challenging to manage in high- surgical-risk patient. We are increasingly encountering such mixed etiologies in valve disease. #3DEcho 🔍 shows “anatomical” regurgitant orifice @CASivaram1 @fiore_corrado @iamritu @alcantaramonica @NMerke @LHoyesWouter @echo_stepbystep @denisamuraru @alexsfelixecho @alex1708ander @najibadn @SwissHeartDoc