Carlos F. Matute-Martínez

Can AI read an ECG like a cardiologist - from just an image? We built ECG-GPT, a vision-text transformer that generates complete diagnostic reports directly from photos of 12-lead ECGs Now out in @ESC_Journals #EHJDigitalHealth Kudos to @aakhunte & @Veer_Sangha_ for leading this @cards_lab 🧵

Among patients with atrial fibrillation at high risk for stroke and bleeding, left atrial appendage closure was not noninferior to medical therapy in reducing the risk of stroke, embolism, major bleeding, or death at 3 years. Full CLOSURE-AF trial results: nejm.org/doi/full/10.10… Editorial: Left Atrial Appendage Closure — Another Overused Method in Cardiology? nejm.org/doi/full/10.10…

The AMA applauds bipartisan legislation to exempt international medical graduate physicians from the $100,000 H-1B visa fee - a critical step to ensure patients, especially in underserved areas, have access to care. Thank you to @RepMikeLawler, @SanfordBishop, @MaElviraSalazar, and @RepYvetteClarke for introducing the bill, and we call on Congress to act quickly to protect patients’ access to care. spr.ly/6010B6r31q

Blood Supply of the Cardiac Conduction System — Summary ■ SA node: ▪︎ 60% from Right Coronary Artery. ▪︎ 40% from Left Circumflex Artery. ■ AV node: ▪︎ ~85–90% from Right Coronary Artery. ▪︎ ~10–15% from Left Circumflex Artery. ■ Bundle of His: ▪︎ Proximal: Right Coronary Artery. ▪︎ Distal: Septal branches of Left Anterior Descending Artery. ■ Right bundle branch: ▪︎ Septal branches of Left Anterior Descending Artery. ■ Left bundle branch: ▪︎ Septal branches of Left Anterior Descending Artery. ✅ Key pearl: ● RCA infarction → sinus node dysfunction & AV block. ● LAD infarction → bundle branch blocks. #cardiology

1. Let me share a story, as to why I love this latest paper from our group. Recently, our resident Ali Hakimi saw a patient who was on anticoagulation and needed carotid stent (TCAR). In discussing postoperative antiplatelet management with faculty, it became clear that there

Use of the Electrocardiogram in Acute Myocardial Infarction | New England Journal of Medicine nejm.org/doi/full/10.10…

Left atrial appendage occlusion device embolization 😱. Remember your checkpoints 🛑: 🟦 WATCHMAN → PASS criteria P – Position: ≥50% of device within the LAA A – Anchor: Anchors engaged with stable fixation (tug test) S – Size: Appropriate compression target 8–20% S – Seal: Adequate closure with no peri-device leak >5 mm 🟩 AMULET → CLOSE criteria C – Circumflex: ~⅔ of the lobe distal to the LCx plane L – Lobe: Lobe appropriately compressed O – Orientation: Coaxial alignment with the LAA axis S – Separation: Clear separation between lobe and disc E – Ellipse: Disc assumes a concave/elliptical shape indicating good apposition #LAAO #EPeeps #iecho #Echofirst #Cardiotwitter #CardioX

Atlas of Regional Left Ventricular Scar in Nonischemic Cardiomyopathies: Substrates and Etiologies | JACC: Advances jacc.org/doi/10.1016/j.…

📌 Management of #athletes 🚴‍♀️ with 👉 Premature ventricular contractions-#PVCs 🔷 accord. to a consensus statement of #EAPC-#ESC #EPeeps #SportsCardiology #CardioTwitter #MedTwitter #ECG @gherardobis @SSharmacardio @SilCastelletti @adribaran @s_gati @Hragy @DrRoderickTung

Abnormal electrocardiogram findings in athletes | European Heart Journal | Oxford Academic academic.oup.com/eurheartj/adva…

Digitoxin is beneficial in reducing the combined risk of #HeartFailure hospitalization and all-cause mortality in patients with systolic HF. Read an expert analysis for more insights ➡️ bit.ly/3XYKV5l #CardioX

Recent discoveries on the acquisition of the highest levels of human performance | Science science.org/doi/10.1126/sc…

2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease ahajrnls.org/4pKvfPc

Multiple gated cardiac blood pool imaging for left ventricular ejection fraction: Validation of the technique and assessment of variability - American Journal of Cardiology ajconline.org/article/0002-9…

Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in acute coronary syndromes: The multicenter, randomized, blinded, IVUS-ACS Trial pcronline.com/News/Whats-new…

🩺 How Aspirin Prevents Cancer Metastasis—Finally Explained For over 50 years, aspirin has been linked to reduced cancer metastasis—but why remained unclear. New mechanistic work now provides a clear immunologic explanation. 🔬 Key Discovery Yang et al. identify a platelet-driven immunosuppressive pathway that prevents T cells from eliminating metastatic cancer cells. Central to this mechanism is ARHGEF1, a protein in T cells activated by thromboxane A₂ (TXA₂)—a platelet metabolite generated via COX-1, the very pathway inhibited by low-dose aspirin. 🧠 What the data show • TXA₂ signaling suppresses T-cell–mediated clearance of metastases • Genetic deletion of ARHGEF1 in T cells reduces metastatic burden • Low-dose aspirin blocks this pathway by irreversibly inhibiting platelet COX-1 • Aspirin’s antimetastatic effect disappears when ARHGEF1 is absent in T cells 🩸 Why low-dose aspirin works Once-daily 75–100 mg aspirin permanently suppresses TXA₂ production in platelets (which cannot resynthesize COX-1), explaining its long-recognized anticancer effects—distinct from its higher-dose anti-inflammatory actions. 💡 Clinical implications • Platelets actively promote metastasis and immune evasion • Immunogenic tumors may benefit most from aspirin • Supports clinical data in Lynch syndrome and PIK3CA-mutant colorectal cancer • Identifies immune biomarkers that may predict aspirin benefit 🔍 Bottom Line Aspirin’s anticancer effect is not nonspecific—it is immune-mediated, platelet-dependent, and mechanistically defined. This work revives interest in repurposing a low-cost, globally accessible drug to prevent cancer progression. nejm.org/doi/full/10.10… #CancerMetastasis #Immunology #Platelets #Aspirin #CancerPrevention #Oncology #TumorImmunology #DrugRepurposing

Imaging in the Diagnosis of Cardiac Amyloidosis - ScienceDirect sciencedirect.com:5037/science/articl…

Occluded Artery Trial - American College of Cardiology acc.org/latest-in-card…

Practical 5-stage Clinical Scale for Electrical Storm: the STORM Classification | European Heart Journal. Acute Cardiovascular Care | Oxford Academic academic.oup.com/ehjacc/advance…

Patient undergoing Handgrip in #echofirst showing immediate hemodynamic changes. #3DEchoBerlin ⁦@echo_batman⁩ ⁦@LHoyesWouter⁩ ⁦@argulian⁩ ⁦@alex1708ander⁩