Florian Huber

If you’re working in cancer immunotherapy — this one’s for you. #Neoantigens #CancerImmunotherapy #AntigenPresentation #ImmuneEscape #NatureReviews

A heartfelt thank you to @michal_bassani for giving me the opportunity to co-author this review — I truly enjoyed the journey and the chance to learn so much in the process.

Curious about how tumors outsmart the immune system – and what that means for #cancervaccines? Our latest review in 𝐍𝐚𝐭𝐮𝐫𝐞 𝐑𝐞𝐯𝐢𝐞𝐰𝐬 𝐈𝐦𝐦𝐮𝐧𝐨𝐥𝐨𝐠𝐲 takes you behind the scenes: 🔗 nature.com/articles/s4157… or 🔗 rdcu.be/ezRK9

Our #diaTracer manuscript is out! 10 years ago we established the concept of library-free, direct DIA analysis with DIA-Umpire. DiaTracer now makes it possible to analyze any diaPASEF data, including PTM, semi-tryptic, nonspecific, and even open searches! nature.com/articles/s4146…

🧵Transforming Tumors into Targets @NatureBiotech! NeoDisc pipeline by researchers at the University of Lausanne, Switzerland combines genomics, transcriptomics, and immunopeptidomics to identify the best cancer antigens for personalized immunotherapy: nature.com/articles/s4158… @FlorianHuber_ @michal_bassani

@michal_bassani @FlorianHuber_ @OncoUNILCHUV @Ludwig_Cancer @CHUVLausanne @ISBSIB @vaccinenation Comprehensive AI-enabled pipeline aids development of personalized cancer vaccines #NBTintheNews via @Inside_PM insideprecisionmedicine.com/topics/oncolog…

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@michal_bassani @FlorianHuber_ @OncoUNILCHUV @Ludwig_Cancer @CHUVLausanne @ISBSIB NeoDisc pipeline enables personalised cancer immunotherapy #NBTintheNews via @vaccinenation vaccinenation.org/technology/neo…

Wow, NeoDisc is an amazing pipeline that characterizes neoantigens, TAAs, TSAs, viral antigens, and antigen presentation defects with genomic, transcriptomic, immunopeptidomic data. It includes TE expression 🤯! Congrats to the pioneer @michal_bassani, @FlorianHuber_ , and team!

@aiinlabcoat Thank you so much, Bauris, for this wonderful breakdown of NeoDisc! I’m glad you captured the essence of our work so well. Really appreciate your support and recognition!

NeoDisc is a new pipeline for finding cancer-specific antigens to advance personalized immunotherapy. Unlike current tools, it combines data from genomics, transcriptomics, and mass spectrometry to identify the most promising targets. By blending rule-based and machine learning methods, NeoDisc makes it easier to select effective neoantigens for cancer vaccines and treatments, pushing precision cancer care forward. Cancer immunotherapy works best when it’s personal. NeoDisc’s approach, finding the best antigens to target for each patient, could mean more effective treatments and fewer side effects for people fighting cancer. Research by: @michal_bassani @FlorianHuber_ @OncoUNILCHUV @Ludwig_Cancer @CHUVLausanne nature.com/articles/s4158…

@Nakul2234 @michal_bassani Thank you so much, Nakul! I’m thrilled that you found NeoDisc as exciting as we do. Appreciate your support!

@riseagainstca @NatureBiotech @michal_bassani @OncoUNILCHUV @Ludwig_Cancer @CHUVLausanne @ISBSIB Thank you for the kind words and support! Much appreciated!

A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy go.nature.com/4eEVVvo

New online in @NatureBiotech by @michal_bassani group: The neoantigen discovery pipeline NeoDisk incorporates mass spectrometry immunopeptidomics data. @FlorianHuber_ @OncoUNILCHUV @LudwigCancer @CHUVLausanne @ISBSIB

@nesvilab @michal_bassani @HippHupo Thank you @nesvilab! We’re happy to have integrated great and sensitive tools like #MSfragger and #FragPipe in #NeoDisc!

@michal_bassani @FlorianHuber_ @HippHupo Congratulations on your publication, and thank you for incorporating #MSfragger and #FragPipe for immunopeptide identification and quantification in your NeoDisc antigen discovery pipeline.

Delighted to share our paper on the NeoDisc pipeline, developed by the super-talented @FlorianHuber_. NeoDisc is an ‘end-to-end’ clinical antigen discovery pipeline, integrating genomics, transcriptomics and immunopeptidomics nature.com/articles/s4158… @HippHupo

Scientists led by Ludwig @OncoUNILCHUV's @FlorianHuber_ & @michal_bassani report NeoDisc, a computational pipeline that integrates molecular/genetic analyses of tumors + targets of T cells and harnesses AI to design personalized cancer vaccines. bit.ly/4eFqe59

Thank you @NatureBiotech for the great overview on NeoDisc in the Research briefing nature.com/articles/s4158…