
We developed a single-molecule, multi-modal spatial genomics approach to visualize the structure and function of >100,000 individual extrachromosomal DNA (ecDNA) molecules in their native contexts. Preprint link at the end of the thread. (1/11)
Frank Furnari
99 posts

@FurnariLab
cutting edge genetics and tumor biology research lab focused on characterizing and developing therapeutic strategies for brain cancer

We developed a single-molecule, multi-modal spatial genomics approach to visualize the structure and function of >100,000 individual extrachromosomal DNA (ecDNA) molecules in their native contexts. Preprint link at the end of the thread. (1/11)


Very exciting and inspiring study coming out from the lab led by @brettmaxtaylor and Weixiu Dong. A method to measure copies, structure, both cellular and intracellular distribution of ecDNA and how these are associated with GBM. Check it out!











**Mark your calendars** Dr. Sean Morrison will be here Thursday, June 12 at 9:30am to speak on the Hematopoietic Stem Cell Niche and Implications for Clinical Transplantation. @ucsdstemcell @SSCDiscovery @UCSDMedSchool @sbpdiscovery @salkinstitute Zoom: ucsd.zoom.us/j/95780022234








Chromatin interactions profiles are useful, but how can we deconvolute cell-type info from the complex tissues? 🎯 Led by @LeiChangpku , we just released Droplet Hi-C: a faster, cheaper, and high-throughput single-cell Hi-C method using microfluidics: nature.com/articles/s4158…

