GiussaniLab

Natural daylight and improved glucose control in Type 2 diabetes cell.com/cell-metabolis… @Cell_Metabolism

Congratulations to Zhongchao Wang from @PDN_Cambridge for winning the Early Investigator Prize 2024 in the #General physiology category! 🔎 🏆 📜 Read the winning paper here: buff.ly/rj9JfAp 🔗 See the full list of winners: buff.ly/HnHdfqa

Hamilton et al found hyperactivity of the cardiac #RyR promotes structural remodeling of #mitochondria. Learn how preventing mitochondrial remodeling can attenuate calcium-dependent #arrhythmia at ahajrnls.org/3Kw6fMp @S_HamiltonLab @jinxi_wang22 @OhioStatePCB

Congratulations to Dr Anna Cochrane! Our newly minted doctorate from the Giussani Lab at University of Cambridge, who passed her PhD viva with flying colours! I couldn’t be prouder of Anna’s work investigating obesity in pregnancy and its effects on the fetus. 🤩

Cool new paper from the @ozannelab showing maternal iron homeostasis, not placental dysfunction, is associated with fetal hypoxia at e13.5 in obese mouse pregnancy physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

101 Questions to Ask Your Papers #Ad

A recent study (shared below) reminded me that 𝐰𝐡𝐚𝐭 𝐦𝐚𝐤𝐞𝐬 𝐚 𝐏𝐡𝐃 𝐬𝐭𝐮𝐝𝐞𝐧𝐭 𝐡𝐚𝐩𝐩𝐲 𝐢𝐬 𝐧𝐨𝐭 𝐩𝐮𝐛𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐨𝐫 𝐬𝐭𝐢𝐩𝐞𝐧𝐝𝐬, 𝐛𝐮𝐭 𝐠𝐨𝐨𝐝 𝐬𝐮𝐩𝐞𝐫𝐯𝐢𝐬𝐢𝐨𝐧. Over the years, I have supervised 53 PhD students, and I can say with conviction that 𝘁𝗵𝗲𝗿𝗲 𝗶𝘀 𝗻𝗼 𝘀𝗶𝗻𝗴𝗹𝗲 𝘀𝘂𝗽𝗲𝗿𝘃𝗶𝘀𝗼𝗿𝘆 𝘀𝘁𝘆𝗹𝗲 that works for all. Each student is different, and every PhD journey has its ups and downs. With some students, I spent a disproportionate amount of time helping them gain confidence. With stronger ones, my role was to 𝗴𝘂𝗶𝗱𝗲 𝘁𝗵𝗲𝗺 𝘂𝗻𝘁𝗶𝗹 𝘁𝗵𝗲𝘆 𝗳𝗼𝘂𝗻𝗱 𝘁𝗵𝗲 𝗿𝗶𝗴𝗵𝘁 𝗽𝗿𝗼𝗯𝗹𝗲𝗺 𝗮𝗻𝗱 𝗯𝗲𝗰𝗮𝗺𝗲 𝘀𝗲𝗹𝗳-𝗱𝗿𝗶𝘃𝗲𝗻. 𝗘𝗺𝗽𝗮𝘁𝗵𝘆 𝗺𝗮𝘁𝘁𝗲𝗿𝘀. Unless a student gets genuinely interested in what he or she is doing, great work rarely happens. A good 𝘀𝘂𝗽𝗲𝗿𝘃𝗶𝘀𝗼𝗿 𝗺𝘂𝘀𝘁 𝗮𝗹𝘀𝗼 𝗵𝗮𝘃𝗲 𝗴𝗼𝗼𝗱 𝗿𝗲𝗹𝗮𝘁𝗶𝗼𝗻𝘀𝗵𝗶𝗽𝘀 𝘄𝗶𝘁𝗵 𝗰𝗼𝗹𝗹𝗲𝗮𝗴𝘂𝗲𝘀. I never restricted my students from seeking advice from other faculty. In fact, I always encouraged it and built a network they could freely approach. I also followed an 𝗼𝗽𝗲𝗻-𝗱𝗼𝗼𝗿 𝗽𝗼𝗹𝗶𝗰𝘆 - any student could walk into my office anytime for advice. I never had a lab of my own in any institution I worked at. Instead, I built common labs, shared by all, to promote collaboration and collective ownership. I have always believed that the 𝗯𝗲𝘀𝘁 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗲𝗻𝘃𝗶𝗿𝗼𝗻𝗺𝗲𝗻𝘁𝘀 𝗮𝗿𝗲 𝘁𝗵𝗼𝘀𝗲 𝘄𝗵𝗲𝗿𝗲 𝗽𝗲𝗼𝗽𝗹𝗲 𝗮𝗻𝗱 𝗳𝗮𝗰𝗶𝗹𝗶𝘁𝗶𝗲𝘀 𝗮𝗿𝗲 𝘀𝗵𝗮𝗿𝗲𝗱, 𝗻𝗼𝘁 𝗼𝘄𝗻𝗲𝗱. I have always taken 𝗽𝗲𝗿𝘀𝗼𝗻𝗮𝗹 𝗿𝗲𝘀𝗽𝗼𝗻𝘀𝗶𝗯𝗶𝗹𝗶𝘁𝘆 𝗳𝗼𝗿 𝗲𝗻𝘀𝘂𝗿𝗶𝗻𝗴 𝘁𝗵𝗮𝘁 𝗺𝘆 𝗣𝗵𝗗 𝘀𝘁𝘂𝗱𝗲𝗻𝘁𝘀 𝗳𝗶𝗻𝗱 𝘁𝗵𝗲𝗶𝗿 𝗳𝗶𝗿𝘀𝘁 𝗷𝗼𝗯 𝗮𝗳𝘁𝗲𝗿 𝗴𝗿𝗮𝗱𝘂𝗮𝘁𝗶𝗼𝗻. Since most of them worked on industry-supported projects, this was never a problem. Nearly 90% of my PhD students wrote their first peer-reviewed paper with me. Unlike in the US, where professors often get students with prior research experience, 𝗶𝗻 𝗜𝗻𝗱𝗶𝗮 𝘄𝗲 𝘄𝗼𝗿𝗸 𝘄𝗶𝘁𝗵 𝗿𝗮𝘄 𝘁𝗮𝗹𝗲𝗻𝘁 𝗮𝗻𝗱 𝗵𝗲𝗹𝗽 𝘀𝗵𝗮𝗽𝗲 𝘁𝗵𝗲𝗺 𝗶𝗻𝘁𝗼 𝗰𝗮𝗽𝗮𝗯𝗹𝗲 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵𝗲𝗿𝘀. Faculty in Indian institutions (at least in the institutions where I worked so far - IIT Bombay, IIT Delhi and BITS Pilani) often put in far more time and effort per student than many of our counterparts abroad. The 𝗿𝗲𝗮𝗹 𝗿𝗲𝘄𝗮𝗿𝗱 𝗰𝗼𝗺𝗲𝘀 𝗳𝗿𝗼𝗺 𝘀𝗲𝗲𝗶𝗻𝗴 𝘀𝘁𝘂𝗱𝗲𝗻𝘁𝘀 𝘁𝗿𝗮𝗻𝘀𝗳𝗼𝗿𝗺 𝗶𝗻𝘁𝗼 𝗰𝗼𝗻𝗳𝗶𝗱𝗲𝗻𝘁 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵𝗲𝗿𝘀, 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗼𝗿𝘀, 𝗮𝗻𝗱 𝘁𝗲𝗮𝗰𝗵𝗲𝗿𝘀. That makes everything worthwhile.

The US DOHaD Society is looking forward to attending the 13th DOHaD World Congress in Buenos Aires, Argentina! Will we see you there? Check out our latest post with a quick survey to help you meet up with other US DOHaD Society Members: usdohad.org/2025/08/20/con…

Sudhahar & colleagues found #exercise protects blood vessel in #diabetes by turning on natural #antioxidants (#SOD3) that produce physiological levels of hydrogen peroxide to keep blood vessels healthy. Learn more at ahajrnls.org/3IU4wz5

Free for all Eurodohad members! Join us for this hybrid meeting. Don’t miss this great opportunity to connect and network

We're here, looking forward to welcoming everyone for day 1 of our annual meeting 'The Placenta at Term' @ChurchillCol

Don't loose this opportunity to join us in Buenos Aires! Late-Breaking Abstract Submission ends on July 14. @DOHaD2025 @DOHaD_Society @DOHaDChile @BrasilDohad @EuropeanDOHaD @USDOHaD @Dohadcanada

Our latest report highlights an important window of opportunity in the first 1,000 days of life to prevent childhood obesity and set children on a healthy path for life. 🗞️ Read @DailyMail for more: bit.ly/4lzIAr6 📙 See the full report: bit.ly/4eAt6ku

How much does severe early‐onset fetal growth restriction cost for hospitals & parents? Find out here in our economic assessment obgyn.onlinelibrary.wiley.com/doi/10.1111/14… Of 135 births, 46% were extremely preterm <28+0 weeks, costing an extra mean £157 832 per infant compared to term birth @ucl

This highlights the need for long-term cardiovascular follow up in offspring (of both sexes!) from human metformin-treated pregnancies to inform decisions about its use in pregnancy - a tricky question that requires balancing mum and baby's health 👩‍🍼

Membership renewal is now available! Be sure to renew your membership by June 30th to keep your member status & continue receiving member benefits. Renew simply by logging into your SRI account, selecting the 'Dues' tab on your dashboard, & continuing to renew your membership!

We were delighted to host the @Cambridgecardio monthly talk with guest speaker Norbert Weissmann from @jlugiessen discussing; Tobacco smoke-induced pulmonary hypertension & lung emphysema.

👥Meet our Members!👥 Dr. Emmanuel Amabebe is a researcher at UTMB Galveston studying molecular pathways behind preeclampsia, preterm birth & more. Dr. Amabebe is a part of the Menon lab & teaches reproductive biology & physiology to both undergraduate & postgraduate students.

This is a very exciting time for research into Hyperemesis Gravidarum (HG) and we are fully supportive of International HG Awareness Day taking place today- 15 May 2025. #HGProgress #IHGAD25 #HyperemesisGravidarum #PregnancySicknessSupport

Congratulations to the @Gates_Cambridge Class of 2025, who have been awarded scholarships in Gates Cambridge 25th year. A very warm welcome also to Tess Stanley and Yimeng Wang, who will be joining the PDN community! We look forward to working with you cam.ac.uk/stories/gates-…