Daniel Barber, PhD

In @elife: Selective JAK Inhibition Reveals Paradoxical and Hierarchical Control of interferon-γ-driven Autoimmunity in AIRE Deficiency doi.org/10.7554/eLife.…

@RobertPRousseau Thanks Rob!

@danielleobarber Cool paper Dan, well done to you and your team. S Fig 1h could be a new profile picture if you wanted to update it 😉.

So we blocked IFNγ in Mtb infected macaques and….the animals were fine. Turns out mice overestimate the importance of IFNγ in TB because IFNγ drives iNOS in mice but not macaques or humans. This means we don’t actually know how T cells suppress Mtb. rdcu.be/ff9GB

@yufanzheng7 @LabWaggoner Thanks Ivan!

@danielleobarber @LabWaggoner Congrats, Dan and your team!

@Sutherland_TB @mayer_barber Thanks Jayne!

@danielleobarber @mayer_barber Wow! Excited to read.

@fyarovinsky Thanks Felix!

@danielleobarber A very interesting story! I’m looking forward to diving into it this weekend and discussing it at journal club.

@javid_lab @mayer_barber Thanks Babak! This one took a while, lol.

@danielleobarber @mayer_barber Glad this is finally out in the wild Dan!

@MazDivangahi Thanks Maz!

@danielleobarber Dan this is a beautiful study and truly shows how much we don’t know about immunity against TB and subsequently questions our current approach for developing TB-vaccine!

We still don’t understand how T cells control tuberculosis. Our new paper shows that Mtb-specific T cells in NHP and human lung granulomas make many interesting effector molecules upon TCR stimulation. There’s a whole lot more to T cells in TB than IFNγ! cell.com/iscience/fullt…

We are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top infectious killer check us out. The NIH intramural program is an amazing place!

We are looking for post-docs! If you are interested in T cell responses to M. tuberculosis infection check us out. The NIH Intramural program is a great place to train!

Happy to share authors.elsevier.com/sd/article/S10… @CellPress Immunity. CD4 T cells contribute to protection against #TB in a reinfection macaque model by interacting with CD8s to generate an anti-inflammatory granuloma environment. Kudos to first authors Sharie Ganchua and @joshuabromley21

Scientists at @NIAIDNews examined the roles of the prototypic pro- and anti-🌡️ #inflammatory cytokines IFNγ and IL-10 using the rhesus macaque model of mild #COVID19. 👇 Check out their discovery on the role of IFNγ in lung lesions. @PLOSPathogens | bit.ly/4f177To

We are looking for a technician to join our team working on immune responses to tuberculosis in NHP models. The NIH is a super fun place to do research. Have a look! guidehouse.wd1.myworkdayjobs.com/en-US/External…

Incredible study from @LionakisLab !!!

@Tcellogic This is amazing!! Congrats Sue!!

I am still in shock and so honored and humbled by the news today! This NAS award is first and foremost for the Kaechians and all their incredible ideas, hard work, and discoveries. Thank you to all my mentors and role models for your support! We all get a gold start today!!

Check out the new paper from Kat Mayer-Barber’s lab. Heterogeneity in outcomes of SARS-CoV-2 may be in part due to the recent pulmonary immune history of the host.

Next article in the lead up to #WorldTBDay 🫁 on March 24: @TaylorForeman19, @danielleobarber et al. show that, in mice, CD30 drives T cell differentiation and is required for host survival of Mycobacterium #tuberculosis infection ➡️ hubs.la/Q02pR6Y-0 #endTB

We are looking for post-docs interested in studying T cell responses to M. tuberculosis infection. The NIH intramural program is an amazing place to train! Check us out.