Ross 🧬🔬

Bryan Johnson reveals why he uses an umbrella even when it’s not raining and UV levels are low “90% of physical skin aging is from the sun, so this is a UV umbrella protecting me”

Taking a food out of your diet you've long consumed often leads people to feel better. First conclusion "this food must have been bad" But as the text attached suggests, you likely can develop nuanced relationships with food based on your nutrient or caloric status. But at the same time, foods that were consumed during sickness, may cause aversions too. There are likely many layers to this - considering the gut has taste receptors which can communicate with your gut bacteria bidirectionally. This is likely a sophisticated mechanism for animals to prioritise food they need and keep them healthy. Moral of the story: food rotation is king.

Iron overload via excess intake being this common villain of health we should all be concerned about is wild fear mongering in my view. Your body has a sophisticated iron regulation system. Some people have genetic variations. They need to be careful. But even with this, it should be clear in your bloodwork. So where does all the fear mongering come from? To raise concerns about even moderate iron intake - many cite studies showing high cellular iron in certain pathologies. This is rarely an intake issue. It's most likely inflammation (or low copper). Consider endometriosis. Many with this condition have excess iron in the overgrown tissue on the endometrium. While over half of these women have iron deficiencies. What could look like iron overload clearly isn't once you add context. It's inflammation raising hepcidin - which traps iron in cells while preventing intestinal absorption. The next part of the confusion likely comes from blood tests people can't interpret. High serum iron is regularly interpreted as iron overload. But even fasting over 12 hours raises serum iron significantly. How many people do you know have dinner at 7pm? Do they get their blood test drawn before 7am the next day? No they do not. Next, many over interpret high transferrin sat % as overload. But it's not always. It's just calculated by iron divided by TIBC x 100. So if iron is normal, and transferrin is low (because of inflammation), iron sat % will look elevated. And ferritin is also often over misconstrued as an iron overload marker. It commonly raises from liver burden or inflammation. As you can see - there are many basic traps. I view bloodwork all day, every day. The iron overload epidemic is not here. Yes some people genuinely do have it - and it can be life changing when they correct it. But the fear mongering about this topic is overkill. If you're worried, check your iron panel. It will be clear as day what you should and shouldn't be worried about.

21-year-old natural athlete will beat a 40-year-old enhanced athlete in many speed/power sports Because youth is the original PED And This is why you also see age-related declines in elite-athlete performance curves

One variable I am seeing left out about the enhanced games is just the basics of effort, drive, training, accountability. How many of the enhanced athletes are training with superhuman effort? How many of them took a long break and lost that fitness block they developed from their youth? Reminds me of when an gold medal swimming olympian stopped training for a year. Tried to make a come back. trained for a couple years. Couldn't even qualify for next olympics.

This is utterly heartbreaking and a terrible reality for women, but endometriosis is literally estrogen dominance. The condition involves the liver and the pituitary gland, but estrogen is central to the formation of the lesions or abnormal tissue associated with endometriosis. The cells in the endometrial tissue begin producing estrogen through the enzyme aromatase, which is typically found in various tissues under stress. This production of estrogen leads to inflammation and pain due to the activation of the cyclooxygenase enzyme, which converts polyunsaturated fatty acids into prostaglandins. These prostaglandins cause inflammation, pain, and other symptoms of endometriosis. Addressing estrogen dominance is paramount. Hose Kate and all the other ladies suffering from Endo with Progest E immediately!!! (Tweet that I’m pinning below will help.)

Just when you thought you understood the power of genetics, along comes the Enhanced Games to remind you.