Inclusive New Normal
748 posts

Inclusive New Normal
@InclusiveNew
Sharing international Covid-related new learning, opportunities and creativity; driving good practice towards a safe Inclusive New Normal. Based in Scotland.





Public Health & 'Close Contact' Most transmission happens close to a source as that is where the pathogen is most! It could be involve any route and it may not include physical contact at all Close contact = we are not sure how it is transmitted but there is space and a time


The PCR positivity map is out, and national levels are holding steady. GP swabbing levels have leapt from 0.6% to 3.3%; per RCGP this looks to be mainly in the north of England. No Scottish data until next week. jamestindall.info/skeuomorpholog… 1/4

Endothelial dysfunction and metabolic biomarkers in post-COVID-19 syndrome 🚨A nightmare study for many! FOR EVERYBODY: 9 months after your COVID-19, your blood vessels are STILL damaged, with probably biomarkers to prove it! 1. Study design: German prospective cohort (n=262 adults) compared blood biomarkers ~37 weeks post-SARS-CoV-2 infection (PCS patients + recovered) versus uninfected controls. 2. Endothelial dysfunction: - Soluble thrombomodulin (sTM) and lactate dehydrogenase (LDH), two established markers of endothelial (blood-vessel) damage, were significantly elevated in the combined infected group (UOC PCS + LIFE Cov+) versus never-infected controls. - So, previously infected individuals had significantly higher soluble thrombomodulin (TM) and lactate dehydrogenase (LDH), independent of PCS diagnosis or fatigue severity. - Critically, there were no significant differences between the PCS group and the LIFE Cov+ group for these markers. 3. Metabolic disruption: - Clear alterations in arginine biosynthesis and taurine/hypotaurine pathways, indicating impaired nitric-oxide (NO) metabolism with reduced L-arginine and taurine levels. →In plain terms: the vascular damage signal was just as strong in the symptom-free recovered people as in those still suffering from fatigue and other PCS complaints. The same held for the metabolic disruptions (impaired arginine biosynthesis and taurine/hypotaurine pathways linked to nitric-oxide production). 4. Fatigue-specific signal: - High-fatigue PCS patients (top MFI-20 quartile) showed elevated linoleic acid (LA) plus monounsaturated fatty acids oleic (OA) and palmitoleic (PA). →The fatty-acid signature specific to high-fatigue PCS adds a potential severity marker. 5. Notes: - Changes persisted already up to 9 months after infection. - PCS remains symptom-based, but these markers offer objective, measurable signals of underlying vascular and metabolic damage! -The discussion and results treat the observed endothelial and metabolic changes as consequences of a single infection and do not speculate on additive damage from subsequent exposures. - Limitations well noted. ‼️So, COVID-19 leaves detectable, objective blood-vessel and metabolic damage in the bloodstream nearly a year later, even if you feel completely fine and never had Long COVID symptoms. Specific fatty-acid spikes flag severe post-COVID fatigue. The “it’s all in your head” narrative for many post-covid people is directly contradicted by these biomarkers! These findings, solidly backed by prior 2021–2025 evidence, prove that COVID-19 inflicts measurable, persistent endothelial and nitric-oxide metabolic damage up to nearly a year later, even in fully symptom-free survivors, thereby supporting the implementation of routine biomarker screening, but even more importantly: #AvoidSars2 #AvoidReinfections. YOU ARE NOW A CV RISK PATIENT! nature.com/articles/s4159…

The multinational outbreak of #hantavirus linked to cruise ship travel should prompt the WHO to change its default response to the risk of airborne transmission bmj.com/content/393/bm…





Meeting next Monday on what impact the #Covidinquiry recommendations are likely to have regarding Health Service and if the #NHS is listening with John Puntis physician and Co Director of #KONP Register at tinyurl.com/55vmbtas #hospitals #HCWS #Covid #Health #cleanair 🏥😷



Covid-19 infections can reactivate dormant cancer cells, & trigger the growth of secondary cancers. There is now compelling medical evidence to this effect. Read the full story on our website: buds.org.uk/covid-and-canc…






🔊 Calling all UK CO₂ monitor owners AND any helpful UK voters PLEASE REPOST ♻️ ❤️ and tag others! 🙏 Can you *please* help us at the local elections next Thursday? - Even if you don't own one, we still need your help! 1/🧵 <Read our new article - next post>






