Inclusive New Normal

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Inclusive New Normal

Inclusive New Normal

@InclusiveNew

Sharing international Covid-related new learning, opportunities and creativity; driving good practice towards a safe Inclusive New Normal. Based in Scotland.

Katılım Haziran 2023
635 Takip Edilen694 Takipçiler
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David Fisman
David Fisman@DFisman·
New paper out in BMC Infectious Diseases, led by Natalie Wilson with Alicia Grima and Clara Lee: how we define hospital-acquired COVID changes whether we see its true mortality burden, and most common definitions hide it. 🧵
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Ruth Ann Crystal, MD
Ruth Ann Crystal, MD@CatchTheBaby·
COVID raises your shingles risk. New data from 110,000+ patients out of Taiwan shows that post-COVID Shingles also raise risk of ➡️ Bell's palsy ➡️ Guillain Barré ➡️ Myasthenia Gravis Worst of all? Neurological vulnerability lasts for at least 3 years. buff.ly/H1N73zd
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WHO/Europe
WHO/Europe@WHO_Europe·
Join our webinar Community Centred Protection Strategies for Long COVID (28/5 at 13:00 CEST). Hear from WHO/Europe, @EU_Health, and Long COVID CSO representatives on tackling false information through WHO Long COVID Mythbusters. Register: luma.com/dk35p9y2
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Dr. med. H. Schiffers, MD, MBA, Lean Sensei
Während der Pandemie habe ich dem @rki_de früh mitgeteilt, das Patienten die nachts Luftfilter am Bett und damit keine 8h täglich mit kontinuierlicher Virus Reinhalation hatten, deutlich mildere #covid Verläufe hatten. Nun bestätigt sich dieser Weg anhand von CT Bildern
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Inclusive New Normal@InclusiveNew·
Close contact is not a mode of infection transmission. Close contact is a space where many modes of transmission can happen (and different modes of transmission require different preventative action). Another great graphic from @EvonneTCurran
Dr Evonne T Curran NursD 💙🇺🇦@EvonneTCurran

Public Health & 'Close Contact' Most transmission happens close to a source as that is where the pathogen is most! It could be involve any route and it may not include physical contact at all Close contact = we are not sure how it is transmitted but there is space and a time

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David Lingenfelter, PhD
David Lingenfelter, PhD@dlingenfelter·
Long COVID shows persistent immune, antiviral, and mitochondrial gene dysregulation 10 months post‑infection, linking IL‑1β, IL‑10, HIF‑1α, and NRF1 to symptom severity. It behaves as a chronic immunometabolic disorder.🧵
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Inclusive New Normal@InclusiveNew·
It's unfortunate that @P_H_S_Official seems to persist with the notion that all respiratory infections are seasonal so there's no need to bother tracking them much over Summer, despite the fact its last big Covid wave was July 2024 & new immune-evasive variants can arise any time
Dan O'Hara@skeuomorphology

The PCR positivity map is out, and national levels are holding steady. GP swabbing levels have leapt from 0.6% to 3.3%; per RCGP this looks to be mainly in the north of England. No Scottish data until next week. jamestindall.info/skeuomorpholog… 1/4

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Inclusive New Normal
Inclusive New Normal@InclusiveNew·
COVID-19 leaves detectable, objective blood-vessel and metabolic damage in the bloodstream nearly a year later, even if you feel completely fine and never had Long COVID symptoms - and there are biomarkers that prove it.
Harry Spoelstra@HarrySpoelstra

Endothelial dysfunction and metabolic biomarkers in post-COVID-19 syndrome 🚨A nightmare study for many! FOR EVERYBODY: 9 months after your COVID-19, your blood vessels are STILL damaged, with probably biomarkers to prove it! 1. Study design: German prospective cohort (n=262 adults) compared blood biomarkers ~37 weeks post-SARS-CoV-2 infection (PCS patients + recovered) versus uninfected controls. 2. Endothelial dysfunction: - Soluble thrombomodulin (sTM) and lactate dehydrogenase (LDH), two established markers of endothelial (blood-vessel) damage, were significantly elevated in the combined infected group (UOC PCS + LIFE Cov+) versus never-infected controls. - So, previously infected individuals had significantly higher soluble thrombomodulin (TM) and lactate dehydrogenase (LDH), independent of PCS diagnosis or fatigue severity. - Critically, there were no significant differences between the PCS group and the LIFE Cov+ group for these markers. 3. Metabolic disruption: - Clear alterations in arginine biosynthesis and taurine/hypotaurine pathways, indicating impaired nitric-oxide (NO) metabolism with reduced L-arginine and taurine levels. →In plain terms: the vascular damage signal was just as strong in the symptom-free recovered people as in those still suffering from fatigue and other PCS complaints. The same held for the metabolic disruptions (impaired arginine biosynthesis and taurine/hypotaurine pathways linked to nitric-oxide production). 4. Fatigue-specific signal: - High-fatigue PCS patients (top MFI-20 quartile) showed elevated linoleic acid (LA) plus monounsaturated fatty acids oleic (OA) and palmitoleic (PA). →The fatty-acid signature specific to high-fatigue PCS adds a potential severity marker. 5. Notes: - Changes persisted already up to 9 months after infection. - PCS remains symptom-based, but these markers offer objective, measurable signals of underlying vascular and metabolic damage! -The discussion and results treat the observed endothelial and metabolic changes as consequences of a single infection and do not speculate on additive damage from subsequent exposures. - Limitations well noted. ‼️So, COVID-19 leaves detectable, objective blood-vessel and metabolic damage in the bloodstream nearly a year later, even if you feel completely fine and never had Long COVID symptoms. Specific fatty-acid spikes flag severe post-COVID fatigue. The “it’s all in your head” narrative for many post-covid people is directly contradicted by these biomarkers! These findings, solidly backed by prior 2021–2025 evidence, prove that COVID-19 inflicts measurable, persistent endothelial and nitric-oxide metabolic damage up to nearly a year later, even in fully symptom-free survivors, thereby supporting the implementation of routine biomarker screening, but even more importantly: #AvoidSars2 #AvoidReinfections. YOU ARE NOW A CV RISK PATIENT! nature.com/articles/s4159…

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Inclusive New Normal@InclusiveNew·
Infection transmits in many ways - tiny aerosols that accumulate like smoke, heavier droplets, & contact when landed on surfaces. All may be more likely at close contact but protection requires different approaches. So, surely all should be the default until proven otherwise?
The BMJ@bmj_latest

The multinational outbreak of #hantavirus linked to cruise ship travel should prompt the WHO to change its default response to the risk of airborne transmission bmj.com/content/393/bm…

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Long Covid Advocacy 💙
Long Covid Advocacy 💙@LongCovidAdvoc·
🩵On #MEAwarenessDay we are sending an open letter to @rcpsych calling for alignment with current evidence. Supported by 20 organisations. +35 advocates, clinicians & academics! In democratic spirit we are offering a public sign-on opportunity 🔗👇️ #RCPsychIC #Garner
Long Covid Advocacy 💙 tweet mediaLong Covid Advocacy 💙 tweet mediaLong Covid Advocacy 💙 tweet media
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Long Covid Scotland 🏴󠁧󠁢󠁳󠁣󠁴󠁿
Today on International ME Awareness Day, we’re calling for better recognition, research & services for people living with ME & Long Covid in Scotland. With £4.5m now allocated by Scottish Government, the focus must now be on accountability & delivering real change for patients.
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Lindsay McAlpine MD
Lindsay McAlpine MD@McAlpineLabYale·
Pleased to share our latest COVID Mind Study @ Yale publication: "Vascular inflammation in neuropsychiatric long COVID" Elevated markers of endothelial adhesion in LC correlates with lower verbal fluency and learning. doi.org/10.1016/j.bbih…
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Cat in the Hat 🐈‍⬛ 🎩 🇬🇧
@danaparish @questlove The tragic truth is that many studies have shown that Covid infections can reactivate dormant cancer cells & trigger growth of secondary cancers. The BuDS Disability Service charity have an excellent summary of the latest research at the link below ⬇️ buds.org.uk/covid-and-canc…
Cat in the Hat 🐈‍⬛ 🎩 🇬🇧 tweet media
BuDS Disability Service@BuDs_UK

Covid-19 infections can reactivate dormant cancer cells, & trigger the growth of secondary cancers. There is now compelling medical evidence to this effect. Read the full story on our website: buds.org.uk/covid-and-canc…

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COVERSE
COVERSE@CoVerseAU·
One of the most important statements on scientific inquiry and public health to emerge in 2026 has come from Akiko Iwasaki at Yale University. Professor Iwasaki has been at the forefront of research into Long COVID, microclots, and post-vaccine syndromes, while also speaking openly about the barriers researchers can face when investigating complex or controversial health conditions. In a recent piece for Nature Reviews Immunology, she argues that science advances by confronting difficult questions, not avoiding them. As she writes: “The field has repeatedly been shaped by ideas that at first seemed divisive but later became foundational. The future of immunology depends on our collective effort to safeguard the freedom of inquiry with the same passion we have for scientific integrity.” Professor Iwasaki later shared that she wrote the piece “to promote thoughtful, respectful, and rational engagement with controversial science topics” and hoped it would encourage constructive dialogue within the scientific community. Open scientific discourse is not a threat to public health. In fact, public trust depends on it. People are more likely to trust institutions that are willing to ask difficult questions, investigate harms transparently, and engage respectfully with uncertainty when it exists. doi.org/10.1038/s41577…
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Zdenek Vrozina
Zdenek Vrozina@ZdenekVrozina·
A new large cohort study in Frontiers in Medicine looked at people who developed shingles after COVID-19. Could shingles after COVID be more than just a painful rash - with possible links to later blood-cancer risk?🧵
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