J Mathew
46.4K posts


Every single person in this comment seems to be confused as to what’s going on. Let me help you out. So what happened was the guy in the red shorts was walking and smoking crack or fent. The dudes that hangout on the streets don’t like that nor do they allow it, especially when there’s kids or women around (so there must have been kids/women around). So to get the point across to the crackhead, so that the crackhead would never do that again, he talked to him with his hands. In NYC we call that sign language.
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Guy at a NYC BBQ minding his own business gets approached by another man and brutally beaten down. Not sure if it was over a burger or some old grudge.
Either way, this is completely
unacceptable. The attacker needs to be arrested immediately.
NYC feels out of control with crime like this happening so casually.
@NYCMayor @GovKathyHochul @NYPDnews — time to get a handle on this. New Yorkers deserve better.
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@PawlowskiMario *grown man spending his entire existence on X talking about politics
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@LadyALover95 Your prime ministers’ grandfather helped the Nazis kill folks in Belgium. Sit this one.
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They found me, oh no. Time to pull out the big guns: YOUR PRESIDENT IS A PEDOPHILE RAPIST.
Davina ❣️🍉@LadyALover95
At the end of the day, we humiliated the fuck out of the Americans and that truly is almost as good as winning the whole thing.
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J Mathew retweetledi

New fantasy football punishment unlocked
New York Post@nypost
Kathy Griffin, 65, reveals new boyfriend on social media: ‘He’s 22’ trib.al/J6zLfBV
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J Mathew retweetledi


@dralexgastro You can perform submucosal lifts. Changing a string should be a breeze 😭
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@J__Mathew My high e popped
Next step is trying to replace that 😂
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The mayor of New York City should get paid more than a mid-level software engineer.

Bill Ackman@BillAckman
.@NYCMayor Mamdani’s appointed advisory commission is recommending an 18.2% raise for himself and other elected officials purportedly because of inflation, yet his self-appointed Rent Guidelines Board — which is supposed to consider inflation in setting rents— froze rents for two years. A question for the mayor: How is this fair or appropriate?
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Imagine handing your baby to an American soldier holy shit
Ma Wukong 马悟空@Ma_WuKong
🇨🇳 Los militares chinos tienen la obligación de servir al pueblo, y si eso implica que tienen que cuidar de tu bebé, tienen que cuidar de tu bebé.
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@dralexgastro There’s a reason the pathology notes “clinical correlation is recommended.”
You and I both know why, just like we both know that the majority of patients who have biopsies of the stomach have gastritis.
Dude just looks for issues.
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@bryan_johnson That is more detailed than the one you shared a few days ago. That is more compelling. Thanks. Best of luck.
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My plan to cure autoimmune gastritis
To our knowledge, no one has ever done this to try and cure an autoimmune disease.
Context: In May, I got diagnosed with autoimmune gastritis (AIG). We found it by taking a tissue biopsy of my stomach. My immune cells are confused, causing my stomach to eat itself.
AIG stops your body from absorbing nutrients like iron and B12, and can eventually lead to cancer. It likely started decades ago when I was diagnosed with hypothyroidism when 21 years old. The thyroid and stomach are closely linked in your immune system.
I feel fortunate that I've been taking such good care of my body for the past five years as my condition would otherwise be much more severe. Millions of people are affected by this disease and are undiagnosed.
Standard of care tells you that you can’t do anything about it. That’s old fashioned.
Here is how we are going to try and cure it:
Step 0: find and diagnose the disease ✅
AIG is rarely caught early because symptoms are subtle. Early warnings are low iron and B12, but when hemoglobin and hematocrit look normal, doctors routinely miss it because there are no obvious signs of anemia.
A standard colonoscopy won't find it either, because it only checks the lower digestive tract, not the stomach. It was only through a highly targeted stomach biopsy that we found it. Even biopsies can miss it if they don't sample the exact right spots. Most people with AIG go undiagnosed.
Step 1: Map my immune system ✅
Last Thursday, I had a blood draw to isolate and decode 1 million of my immune cells. Think of your immune cells as trillions of soldiers. Each carries a unique key designed to unlock and destroy a specific threat, like a virus or bacteria.
A standard blood test allows you to see how many soldiers you have, but not their keys. Sequencing one million individual immune cells allows us to read the exact pattern of the teeth on every single key.
This is important for my autoimmune gastritis (AIG) because a specific platoon of rogue soldiers has developed keys that unlock an attack on my stomach lining.
Right now, we don’t know who they are. This test will inform us of which soldiers have gone rogue and are attacking me from within.
Once we know the soldier and key, we know what therapy path to pursue to shut them down.
Step 2: Catch the rogue soldiers
I will be getting a second biopsy from my stomach because we need to collect live tissue. We are currently planning out the logistics of getting the sample from my stomach to the lab.
We need these live cells because the initial blood tests showed the antibodies, which prove that an attack is happening, but doesn’t show us the actual rogue soldier doing the damage which is a T-cell.
The live sample will allow us to match the immune system mapping we did to the live T-cells.
Step 3: Build an early warning system
To keep an eye on the disease as we work towards a therapy, we’re building an early warning system. I'll have my blood drawn every two weeks and we’ll pair that information with wearable data to look for flare ups. This is important because the attack happens without producing symptoms that I can easily feel.
Step 4: Create a “Bryan in a dish” testing model, a miniature of my immune system
At the same time, we are taking a massive sample of my immune cells and deep freezing them (cryopreservation) for two reasons:
a) we’ll create a living lab: using these cells to replicate my immune environment in a lab dish. This allows us to test experimental drugs and therapies on my actual live cells before putting them into my body.
b) it creates a back up plan for me by preserving the raw cellular material needed for targeted rejuvenation therapies in the future.
Step 5: Build precision guided therapies to end the attack
Once we know who the rogue soldiers are, we will engineer a therapy designed uniquely for them. The trick is only turning off the rogue soldiers while leaving all the other healthy ones functioning as they are.
For safety checks, we’ll do two test runs:
1) we’ll run the therapy through a computer model that has my biology to evaluate how my molecules interact.
2) We will take my actual cells that we froze in Step 4 and watch them interact for real.
If both are successful, we’ll pursue one of four therapies:
a) fix the mistake my cells are making, restoring my immune system's natural off switches
b) teach the rogue cells to tolerate my stomach instead of attacking it
c) design smart molecules that physically plug into the rogue cells and turn them off
d) build soldiers who will track down and eliminate the rogue soldiers causing the damage
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@Nauli1131921 @GolfDegen @allforthanookie No shit. The fat ass American didn’t lower his shoulder, which is why he got lit up.
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@GolfDegen @allforthanookie Bitch, the Handegg dude is taller and bigger and still got fucked by the rugby dude. Sybau
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@Top100Rick “ I can’t believe the best golfer on earth is t wearing a suit and tie..”
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