Jake Thomas

35 posts

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Jake Thomas

Jake Thomas

@JakerrThomas

PostDoc @LabSchlitzer | Human mononuclear phagocytes in chronic inflammation | Previously PhD @McGovernLab

Katılım Ekim 2020
61 Takip Edilen110 Takipçiler
Jake Thomas retweetledi
Tessa Campbell
Tessa Campbell@ScientistTess·
Only in a talk introducing the DC subtypes studied do people say “This is not a political statement, it’s just what we call them here.” 😂 Fab talk from Jake Thomas in @LabSchlitzer on human DCs and their niches in chronic inflammation! #DC2024
Tessa Campbell tweet media
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Jake Thomas
Jake Thomas@JakerrThomas·
Excited to see this work from my PhD with @McGovernLab finally out! The revised study now includes fascinating epigenetics data from @annappios and @cw_hanna showing how HLA class II expression is initially silenced in human primitive macrophages. Check it out! 👇
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Jake Thomas retweetledi
Maria Jose Donde
Maria Jose Donde@MariaDonde2·
Check out our new paper showing how we re-targeted XNAzymes to cleave individual miR and Y RNA! Thanks to everyone involded and especially @Taylor_Lab_Cam.
Alex Taylor@Taylor_Lab_KCL

🚨 New paper in @CommsBio by brilliant student @MariaDonde2 ! We engineer XNAzymes to selectively cleave individual disease-associated non-coding RNAs (microRNAs, Y RNA) in families of similar seqs – a route to precision modulation of RNA networks? #synbio rdcu.be/cWfuE

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Jake Thomas
Jake Thomas@JakerrThomas·
Great study for all those interested in the maternal-fetal interface!👇 trophoblast-dependant reprogramming of decidual macrophages in early pregnancy
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Jake Thomas
Jake Thomas@JakerrThomas·
Huge thanks to everyone involved in this project including @McGovernLab, @MoffettAm485, Andrew Sharkey, Elisa Laurenti, all sample donors and many others! Thanks for reading and we look forward to getting feedback from the community and from reviewers!
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Jake Thomas
Jake Thomas@JakerrThomas·
Together these findings suggest that HLA-DRneg HBC are derived locally from PEMP and demonstrate that human primitive haematopoiesis is not restricted to the yolk sac, occurring also in the placenta.
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Jake Thomas
Jake Thomas@JakerrThomas·
Ever wondered how Hofbauer cells (human fetal placental macrophages) are generated during pregnancy? We aimed to investigate this in our latest preprint! biorxiv.org/content/10.110…
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Keşfet

@NatureComms @karolinskainst @annappios @cw_hanna @ColinYCLee @ClatworthyLab @FrontImmunol @MoffettAm485