Swanee🎱

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Swanee🎱

Swanee🎱

@JaySwansonPool

9-Ball World Champion. Rescue a shelter or street kitty, dog, bunny, or any critter.🐱🐶🐇🐿🕊🐝🐞🐎🐗🐂🦌 🇺🇸🦅

San Diego, CA Katılım Kasım 2018
7.1K Takip Edilen7.3K Takipçiler
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Swanee🎱
Swanee🎱@JaySwansonPool·
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Zdenek Vrozina
Zdenek Vrozina@ZdenekVrozina·
Important new study. ME/CFS and Long COVID are not the same thing. Yes, they can look very similar from the outside - crushing fatigue, PEM, brain fog, dysautonomia. But when researchers looked deeper into the immune system, the biology looked different🧵
Harry Spoelstra@HarrySpoelstra

Comprehensive Immunophenotyping of Monocytes and Dendritic Cells Suggests Distinct Pathophysiology in Chronic Fatigue Syndrome and Long COVID 🚨Interesting new decisive data confirming divergence: ME/CFS and Long COVID are NOT the same disease! ➡️This international study used multiparameter flow cytometry on peripheral blood mononuclear cells to compare immune profiles in ME/CFS (n=103), Long COVID (n=63), and healthy controls (n=41). It targeted monocytes (M1/M2-like), dendritic cells (DCs), and T-cell subsets to uncover disease-specific signatures, ➡️Long COVID Profile: - Marked by increased M2-like monocyte polarization, elevated CD80 (costimulatory marker) across monocyte subsets, DC expansion, and paradoxically reduced activation markers (e.g., CD69+CD38), - Indicates persistent immune activation combined with exhaustion features, ➡️ME/CFS Profile: - Characterized by reduced costimulatory molecule expression (e.g., lower CD80 on DCs/monocytes), impaired CCR7 expression (disrupting immune cell trafficking), and less coordinated activation patterns, consistent with immune suppression, ➡️Additional Analyses: - Correlation networks showed more extensive, integrated immune interactions in Long COVID vs. fragmented patterns in ME/CFS, - Principal component analysis (PCA) and PLS-DA revealed distinct immunophenotypic clusters, enabling moderate discrimination between the two conditions (AUC ~0.76 in moderate cases), ➡️Implications: - Age-adjusted statistics confirmed differences, - Findings point to divergent post-infectious immunopathologies rather than a shared syndrome, ➡️Conclusion: - ME/CFS and Long COVID are not the same disease, - They drive opposite immune failures, one of chronic hyper-activation tipping into exhaustion, the other of outright suppression and trafficking collapse, - Treating them as interchangeable is scientifically indefensible and clinically harmful, - Distinct biomarkers now exist: →Separate pathophysiology demands separate diagnostics and therapies! #MECFS #LongCOVID #AvoidSars2 #AvoidReinfections mdpi.com/1422-0067/27/1…

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Charles Booker
Charles Booker@Booker4KY·
Donald Trump wants a billion dollar slush fund to pay criminals who stormed the Capitol and attacked officers. Even Mitch McConnell had to condemn this mess. Will Andy Barr go along with Trump and support a dirty slush fund for insurrectionists? Kentuckians know the answer.
Kyle Griffin@kylegriffin1

BREAKING: Mitch McConnell just slammed the Trump slush fund: "So the nation's top law enforcement official is asking for a slush fund to pay people who assault cops? Utterly stupid, morally wrong – Take your pick."

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Acyn
Acyn@Acyn·
MacFarlane: Here's the first sign that you have an indefensible idea. You have to pervasively put out false information to defend that idea. The critics of the January 6th prosecutions have alleged it was a Biden launched weaponization. It was Donald Trump's first term in which those prosecutions were launched. It was Trump's department of justice that did so. They called themselves victims of weaponized prosecutions. That assumes that every single grand juror and every single trial juror, hundreds of people were all in on this, which is a preposterous notion.
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Laura Miers
Laura Miers@LauraMiers·
After battling a “sinus cold,” he was “abruptly pulled from the Coca-Cola 600 field with a severe illness resulting in hospitalization.” He died hours later. A May 16th quote: “I’m still not great. The cough was pretty substantial last week.”
NASCAR@NASCAR

We are saddened and heartbroken to share the news of the passing of Kyle Busch, a two-time Cup champion and one of our sport's greatest and fiercest drivers. He was 41 years old. We extend our deepest condolences to the Busch family, Richard Childress Racing and the entire motorsports community.

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BirdieBittern
BirdieBittern@BirdieBittern·
13-Year-Old Baseball Player Goes into Cardiac Arrest During Game in North Carolina An off-duty police officer performed CPR on the teen following the medical emergency He remains on a ventilator This is our new normal, we have to accept this 😷😷 people.com/13-year-old-ba…
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PatriotTakes 🇺🇸
PatriotTakes 🇺🇸@patriottakes·
Katie Miller: “What’s a conspiracy theory that you believe in?” Liz Wright, wife of Trump Energy Secretary Chris Wright: “…The teachers unions want to keep the students stupid so they can control them and turn them into Democrats.”
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Acyn
Acyn@Acyn·
Rep. Norman: January 6th was an issue that was made up in the first place. Reporter: Made up? Norman: That was a staged thing from day one. Reporter: The riot was staged? Your Republican colleagues barricaded themselves in their chamber. You think they were acting?
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Democracy Docket
Democracy Docket@DemocracyDocket·
NEW: Colorado Democrats voted to formally condemn and censure Gov. Jared Polis (D) over his decision to grant prominent election denier Tina Peters clemency. By censuring him, Polis won't be allowed to participate as an "officially recognized representative" at any Democratic-sponsored events. democracydocket.com/news-alerts/ti…
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Brown Eyed Susan
Brown Eyed Susan@smc429·
Oh, look at who the second name on the list belongs to
Brown Eyed Susan tweet media
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Gavin Newsom
Gavin Newsom@GavinNewsom·
The Voting Rights Act was bipartisan law for decades. Then SCOTUS handed red states carte blanche to RIG elections and SILENCE voters. WAKE UP.
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The Shallow State
The Shallow State@OurShallowState·
We've gone from being a country with a constitution and presidency that was respected and revered by all the free world, to a corrupt and reviled country filled with conflict of interest, that is pillaging the people of the free world, all from the office of its presidency.
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Amber Woods @ Amber Speaks Up
🔥 Maybe Americans should start asking how many members of Congress hold dual citizenship or own homes overseas while making decisions that affect our future here.
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Occupy Democrats
Occupy Democrats@OccupyDemocrats·
BREAKING: YES! Congressman Ro Khanna shatters the emergency glass and calls for expanding the Supreme Court to 13 justices and term limiting their seats. We're done letting this corrupt institution destroy our democracy... "We must stand up to this modern day Dred Scott Court," Khanna said in a video posted to X, referring to an infamous 1857 Supreme Court pro-slavery ruling which held that Black people could not be citizens under the Constitution. "They have unleashed a process that will eliminate the only Black majority district in the state of South Carolina. ," Khanna continued. "South Carolina has a Black population of 25%, but they would be left with not a single Black majority district or Black political representation in the house." "We need term limits for these justices now. And we need to expand the Supreme Court from nine to 13 justices," he concluded. Bravo congressman. Short, sweet, and to the point is the best way to handle this messaging. This court has totally shredded its legitimacy by handing down one far-right ruling after another in contradiction of legal precedent, good judgement, and moral valence. Clarence Thomas has been bought and paid for by conservative billionaire Harlan Crow and Samuel Alito is every bit as corrupt, having accepted bribes in the form of luxury fishing trips and private jet travel from billionaire Paul Singer. Corporations and oligarchs control our court and the only way to remedy that problem is to expand it, nominating justices who actually care about the rights and interests of the American people. The alternative is to do nothing and watch as Republicans exploit the court to implement their deeply unpopular, minoritarian, fascist agenda. The gerrymandering assault on Black voters that Khanna mentioned is just the beginning. If we don't act now, the court will strip away more and more of our democracy until all that remains is white Christian rule. Do you support expanding the court? How many justices should we add? Do you have any concerns about the process? Please ❤️ and share if you support expanding the court!
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MayoIsSpicyy
MayoIsSpicyy@Mayoisspicyy·
Trump's insurrection never ended.
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