Kehat Lab

Join us in Minneapolis for the 2026 ISHR North American Section Meeting! 📍 Minneapolis, MN 📅 May 31–June 3, 2026 Promoting the next generation of basic and translational scientists. Reserve your spot today! #ISHRNAS2026 ishrnorthamerican.org/meetings/

Ghiringhelli et al bioengineered a human-like #atrial heart model that reproduces complex #arrhythmias & can be precisely controlled with light (#optogenetics). Learn about this new platform for studying #AFib at ahajrnls.org/4tVnVCr

What Mr. Trump’s career in business and politics has made clear is he understands one concept better than any other: leverage. open.substack.com/pub/thomasvond…

Huge congrats to Dr. Jop van Berlo (@UMNews) and Dr. Silvia Guatimosim (UFMG) on receiving the @American_Heart International Visiting Professor Award. They’re combining forces to tackle the complexities of cardiac remodeling and molecular cardiology. #Cardionerds #UMNresearch

@rbdamgaard @BarteltLab This will help break the impact factor bubble, which I don’t think advances science

@KehatLab @BarteltLab I see your point, but I don’t think that makes sense once the peer-reviewed version is published.

Why not cite preprints? They are published, the data are there for everyone to see. Why ignore the latest data of out of principle?

@Ramihdd & colleagues by charting the heart cell #proteome & using #CRISPR for precise validation, identified a key protein that sustains the heart #proteostasis & preserves #mitochondrial protein levels. Find out more at ahajrnls.org/3NFIQJG @KehatLab

New #SkeletalMuscle paper: FibroTrack: a standalone deep learning platform for automated fibrosis quantification in muscle and cardiac histology. tinyurl.com/4vt9f6z4

Finally out: We used CRISPRa/i to show that virtually ANY genomic site can become regulatory for cardiac genes—even without accessibility or active marks. TF recruitment remodeled chromatin & changed expression up to 70 kb away. doi: 10.1016/j.isci.2025.114040

Tucker is indeed a scavenger, and the carcass he ransacks is the once great tradition of conservative thought in this country. thomasvondriska.substack.com/p/on-the-maga-…

@IgorUlitsky Cut the product with Dpni. It cuts only methylated A. The plasmid is from bacteria and has methylated A, but the PCR product doesn’t

Any great tips out there for getting rid of transfected plasmids before doing qRT-PCR?

1/ Can #Axolotls teach us new things about #HeartRegeneration? A great collaboration between @Tanaxolotl and Miguel Torres lab. We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that? doi.org/10.64898/2025.…

Excited to launch the Landau-Levi Lab at @TechnionLive ! We develop organ-on-a-chip systems focused on cardiac and multi-organ interactions and the role of immune cells in shaping tissue function. Learn more: thelandaulab.com

We look forward to welcoming you in #Birmingham @VisitBritain @ISHR_ES @unibirmingham

Quantifying cardiomyocyte contraction & nuclear deformation interaction reveals nucleus-damaging mechanism underlying LMNA cardiomyopathy 📷 @AmiadDaria & @julieheffler et al @WeillCornell @PennMedicine in @NatureCVR ➡️ bpod.org.uk/archive/2025/1…

@RackMada מצטער אבל חייב לתקן: אחוז החמצן הוא 21.9% בכל הגבהים. מה שיורד הוא הלחץ החלקי של החמצן

חמצן חיוני לגופינו וריכוזו החלקי בגובה פני הים הוא 21%, כאשר נטפס לגובה, ריכוזו החלקי יקטן. בגובה של כ3000 מ מעל פני הים הוא ירד לכ14% ב5000 מ הוא יהיה כ11%. התנאים הללו נקראים היפוקסיה, או חוסר בחמצן. ויש תוצאות ביולוגיות מפתיעות לאנשים ששוהים בגבהים הללו. בתחילת שנות ה60 היתה>